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Bengt Samuelsson

Bengt Samuelsson

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Biology and Biochemistry
Sweden
2023
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Chemistry
Sweden
2022

D-Index & Metrics

Chemistry

D-Index
123
Citations
67183
World Ranking
433
National Ranking
4

Biology and Biochemistry

D-Index
129
Citations
65854
World Ranking
421
National Ranking
8

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2022 - Research.com Chemistry in Sweden Leader Award
  • 1990 - Fellow of the Royal Society, United Kingdom
  • 1988 - Member of Academia Europaea
  • 1984 - Member of the National Academy of Sciences
  • 1982 - Nobel Prize for their discoveries concerning prostaglandins and related biologically active substances
  • 1982 - Fellow of the American Academy of Arts and Sciences
  • 1981 - Canada Gairdner International Award
  • 1977 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Bengt Samuelsson was affiliated with the Karolinska Institute in Sweden. Their research spanned multiple fields including biochemistry, genetics, molecular biology, and medicine. Their work contributed to subfields such as cancer research, molecular biology, pharmacology, immunology, and pulmonary and respiratory medicine.

Their scientific output focused on topics including microRNA in disease regulation, immune response and inflammation, neonatal respiratory health research, advanced glycation end products research, cancer-related molecular mechanisms, RNA research and splicing, and RNA interference and gene delivery.

Frequent collaborators in their research included Jesper Z. Haeggström, Stella Uebbing, Marius Kreiß, Ulrike Garscha, and Oliver Werz.

Samuelsson published in multiple scientific journals, with a notable number of papers in the Proceedings of the National Academy of Sciences, The FASEB Journal, the International Journal of Molecular Sciences, and Frontiers in Pharmacology.

Some of the recent papers authored or coauthored by Samuelsson were:

  • "Human leukocytes selectively convert 4 S,5 S -epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer" (2021, Proceedings of the National Academy of Sciences)
  • "Modulation of microRNA processing by 5-lipoxygenase" (2020, The FASEB Journal)
  • "Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells" (2020, Proceedings of the National Academy of Sciences)
  • "Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase" (2023, International Journal of Molecular Sciences)
  • "The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes" (2022, Frontiers in Pharmacology)

Throughout their career, Bengt Samuelsson received several professional recognitions and awards. These included the Nobel Prize in 1982 for discoveries related to prostaglandins and biologically active substances, membership in the National Academy of Sciences (1984), Fellowship of the Royal Society in the United Kingdom (1990), and membership in Academia Europaea (1988). Further honors were the Fellow of the American Academy of Arts and Sciences (1982), Canada Gairdner International Award (1981), Albert Lasker Award for Basic Medical Research (1977), and membership in the Association of American Physicians.

Best Publications

  • Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

    Mats Hamberg;Jan Svensson;Bengt Samuelsson

  • LEUKOTRIENES: MEDIATORS OF IMMEDIATE HYPERSENSITIVITY REACTIONS AND INFLAMMATION

    B. Samuelsson

  • Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

    Bengt Samuelsson;Sven-Erik Dahlén;Jan Åke Lindgren;Carol A. Rouzer

  • Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

    Mats Hamberg;Bengt Samuelsson

  • Prostaglandins and thromboxanes.

    B Samuelsson;M Goldyne;E Granström;M Hamberg

  • Leukotriene C: a slow-reacting substance from murine mastocytoma cells.

    Robert C. Murphy;Sven Hammarstrom;Bengt Samuelsson

  • Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response

    S E Dahlén;J Björk;P Hedqvist;K E Arfors

  • Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

    Mats Hamberg;Jan Svensson;Toshio Wakabayashi;Bengt Samuelsson

  • Leukotrienes are potent constrictors of human bronchi

    Sven-Erik Dahlén;Per Hedqvist;Sven Hammarström;Bengt Samuelsson

  • Advances in Prostaglandin and Thromboxane Research

    Bengt Samuelsson;Rodolfo Paoletti;Peter W. Ramwell

  • Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

    Per-Johan Jakobsson;Staffan Thorén;Ralf Morgenstern;Bengt Samuelsson

  • Arachidonic Acid Metabolism in Polymorphonuclear Leukocytes: Effects of Ionophore A23187

    Pierre Borgeat;Bengt Samuelsson

  • Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes

    Charles N. Serhan;Mats Hamberg;Bengt Samuelsson

  • Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.

    P Borgeat;M Hamberg;B Samuelsson

  • Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis.

    Mats Hamberg;Bengt Samuelsson

  • Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides.

    P. Needleman;S. Moncada;S. Bunting;J. R. Vane

  • Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

    Bengt Samuelsson;Ralf Morgenstern;Per-Johan Jakobsson

  • Prostaglandin Endoperoxides. A New Concept Concerning the Mode of Action and Release of Prostaglandins

    Mats Hamberg;Jan Svensson;Bengt Samuelsson

  • Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

    Sven Hammarstrom;Mats Hamberg;Bengt Samuelsson;Elizabeth A. Duell

  • Ribonuclease activity and RNA binding of recombinant human Dicer.

    Patrick Provost;David Dishart;Johanne Doucet;David Frendewey

  • On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase.

    Unknown

Frequent Co-Authors

Olof Rådmark
Olof Rådmark Karolinska Institute
Mats Hamberg
Mats Hamberg Karolinska Institute
Jesper Z. Haeggström
Jesper Z. Haeggström Karolinska Institute
Sven Hammarström
Sven Hammarström Linköping University
Charles N. Serhan
Charles N. Serhan Brigham and Women's Hospital
Sven-Erik Dahlén
Sven-Erik Dahlén Karolinska Institute
Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Ralf Morgenstern
Ralf Morgenstern Karolinska Institute
Takao Shimizu
Takao Shimizu University of Tokyo
Per-Johan Jakobsson
Per-Johan Jakobsson Karolinska University Hospital

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