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Menachem Fromer

Menachem Fromer

D-Index & Metrics

Genetics

D-Index
51
Citations
53999
World Ranking
3814
National Ranking
1643

Overview

Menachem Fromer is affiliated with the Broad Institute in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with specific work in Genetics, Molecular Biology, Plant Science, Cognitive Neuroscience, and Modeling and Simulation.

The scientist's research covers a variety of topics, including:

  • Genomics and Rare Diseases
  • Genetic Associations and Epidemiology
  • Genomic variations and chromosomal abnormalities
  • Genetics and Neurodevelopmental Disorders
  • Chromosomal and Genetic Variations
  • COVID-19 epidemiological studies
  • Infection Control and Ventilation

Menachem Fromer has contributed to multiple publication venues, frequently publishing in:

  • UNC Libraries
  • Nature Communications
  • Nature Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature

Notable recent papers include:

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia, 2022, Nature
  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism, 2020, Cell
  • A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts, 2021, Biological Psychiatry
  • Exome sequencing in schizophrenia-affected parent-offspring trios reveals risk conferred by protein-coding de novo mutations, 2020, Nature Neuroscience
  • Analysis of protein-coding genetic variation in 60,706 humans, 2020, UNC Libraries

Frequent co-authors of Menachem Fromer include:

  • Giulio Genovese
  • Sarah E. Bergen
  • Douglas M. Ruderfer
  • Shaun Purcell
  • Pamela Sklar

Best Publications

  • Analysis of protein-coding genetic variation in 60,706 humans

    Monkol Lek;Konrad J. Karczewski;Konrad J. Karczewski;Eric V. Minikel;Eric V. Minikel;Kaitlin E. Samocha

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

    Giulio Genovese;Anna K. Kähler;Robert E. Handsaker;Johan Lindberg

  • Synaptic, transcriptional and chromatin genes disrupted in autism

    Silvia De Rubeis;Xin-Xin He;Arthur P Goldberg;Christopher S. Poultney

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S. Breen

  • Patterns and rates of exonic de novo mutations in autism spectrum disorders

    Benjamin M. Neale;Yan Kou;Li Liu;Avi Ma'Ayan

  • De novo mutations in schizophrenia implicate synaptic networks

    Menachem Fromer;Andrew Pocklington;David Kavanagh;Hywel John Williams

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • A polygenic burden of rare disruptive mutations in schizophrenia

    Shaun M Purcell;Jennifer L Moran;Menachem Fromer;Douglas Ruderfer

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

    Daniel G. MacArthur;Daniel G. MacArthur;Suganthi Balasubramanian;Adam Frankish;Ni Huang

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Discovery and Statistical Genotyping of Copy-Number Variation from Whole-Exome Sequencing Depth

    Menachem Fromer;Jennifer L. Moran;Kimberly Chambert;Eric Banks

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S Breen;Michael S Breen

  • Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

    Giulio Genovese;Menachem Fromer;Eli A Stahl;Douglas M Ruderfer

  • The PsychENCODE project

    Schahram Akbarian;Chunyu Liu;James A Knowles;Flora M Vaccarino

  • Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases

    Rong Chen;Lisong Shi;Jörg Hakenberg;Brian Naughton

Frequent Co-Authors

Shaun Purcell
Shaun Purcell Harvard Medical School
Douglas M. Ruderfer
Douglas M. Ruderfer Vanderbilt University Medical Center
Benjamin M. Neale
Benjamin M. Neale Harvard University
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Steven A. McCarroll
Steven A. McCarroll Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Aarno Palotie
Aarno Palotie University of Helsinki
Eli A. Stahl
Eli A. Stahl Icahn School of Medicine at Mount Sinai
Pamela Sklar
Pamela Sklar Icahn School of Medicine at Mount Sinai
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai

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