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Michael J. Caplan

Michael J. Caplan

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
15453
World Ranking
8242
National Ranking
3726

Overview

Michael J. Caplan is affiliated with Yale University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with particular concentration on genetic and kidney cyst diseases.

Their recent publications include the following papers:

  • The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion, 2023, Nature Communications
  • Chloride channels regulate differentiation and barrier functions of the mammalian airway, 2020, eLife
  • Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR, 2022, Nature Communications
  • Calcium signalling and transport in the kidney, 2024, Nature Reviews Nephrology
  • A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling, 2020, Cellular Signalling

Frequent co-authors of Michael J. Caplan include:

  • Nikolay Gresko
  • Laura Onuchic
  • Giorgia Schena
  • Valeria Padovano
  • Vanathy Rajendran

The scientist commonly publishes in the following venues:

  • Journal of the American Society of Nephrology
  • Physiology
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Physiology-Cell Physiology

Their main fields of study are in Biochemistry, Genetics and Molecular Biology, and Medicine.

Subfields in which they focus their research include:

  • Genetics
  • Molecular Biology
  • Pathology and Forensic Medicine
  • Cell Biology
  • Pulmonary and Respiratory Medicine

Among the main topics covered in their work are:

  • Genetic and Kidney Cyst Diseases
  • Biomedical Research and Pathophysiology
  • Microtubule and mitosis dynamics
  • Protist diversity and phylogeny
  • Renal and related cancers
  • Neonatal Respiratory Health Research
  • Tracheal and airway disorders

Best Publications

  • Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

    Jennifer L. Pluznick;Ryan J. Protzko;Haykanush Gevorgyan;Zita Peterlin

  • Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

    Marie E. Egan;Marilyn Pearson;Scott A. Weiner;Vanathy Rajendran

  • Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling.

    Arthit Chairoungdua;Danielle L. Smith;Pierre Pochard;Michael Hull

  • The uptake and intracellular fate of PLGA nanoparticles in epithelial cells.

    Malgorzata S. Cartiera;Katherine M. Johnson;Vanathy Rajendran;Michael J. Caplan

  • AMP-activated protein kinase regulates the assembly of epithelial tight junctions

    Li Zhang;Ji Li;Lawrence H. Young;Michael J. Caplan

  • Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.

    Stacey L. Demento;Stephanie C. Eisenbarth;Harald G. Foellmer;Craig Platt

  • Unimolecular segment amplification and sequencing

    Paul M. Lizardi;Michael Caplan

  • Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

    Vinita Takiar;Saori Nishio;Patricia Seo-Mayer;J. Darwin King

  • Low-Flow Ischemia Leads to Translocation of Canine Heart GLUT-4 and GLUT-1 Glucose Transporters to the Sarcolemma In Vivo

    Lawrence H. Young;Yin Renfu;Raymond Russell;Xiaoyue Hu

  • The cell biology of polycystic kidney disease

    Hannah C. Chapin;Michael J. Caplan

  • Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

    Veronique Chauvet;Xin Tian;Herve Husson;David H. Grimm

  • Intracellular sorting and polarized cell surface delivery of (Na+,K+)ATPase, an endogenous component of MDCK cell basolateral plasma membranes

    M J Caplan;H C Anderson;G E Palade;J D Jamieson

  • Dependence on pH of polarized sorting of secreted proteins.

    Caplan Mj;Stow Jl;Newman Ap;Madri J

  • Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells.

    Marie E. Egan;Judith Glöckner-Pagel;Catherine A. Ambrose;Paula A. Cahill

  • Functional expression of the olfactory signaling system in the kidney

    Jennifer L. Pluznick;Dong Jing Zou;Xiaohong Zhang;Qingshang Yan

  • Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity

    Krzysztof Bryniarski;Wlodzimierz Ptak;Asha Jayakumar;Kerstin Püllmann

  • Macrophages Promote Cyst Growth in Polycystic Kidney Disease

    Anil Karihaloo;Farrukh M. Koraishy;Sarah C. Huen;Yashang Lee

  • Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

    Mark Lal;Xuewen Song;Jennifer L. Pluznick;Valeria Di Giovanni

  • Biotinylation and assessment of membrane polarity: caveats and methodological concerns

    Cara J. Gottardi;Lisa A. Dunbar;Michael J. Caplan

  • Cell-specific Sorting of Biogenic Amine Transporters Expressed in Epithelial Cells

    Howard H. Gu;Jinhi Ahn;Michael J. Caplan;Randy D. Blakely

Frequent Co-Authors

Stefan Somlo
Stefan Somlo Yale University
Cara J. Gottardi
Cara J. Gottardi Northwestern University
James D. Jamieson
James D. Jamieson Yale University
Ira Mellman
Ira Mellman Parker Institute for Cancer Immunotherapy
Tong Wang
Tong Wang University of Tennessee at Knoxville
W. Mark Saltzman
W. Mark Saltzman Yale University
Michael Kashgarian
Michael Kashgarian Yale University
John P. Geibel
John P. Geibel Yale University
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco

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