D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 100 Citations 42,849 182 World Ranking 428 National Ranking 252
Best female scientists D-index 103 Citations 44,808 227 World Ranking 778 National Ranking 481

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

1998 - Fellow of the American Academy of Microbiology Genetics and Molecular Biology

1993 - Member of the National Academy of Sciences

1992 - Fellow of the American Association for the Advancement of Science (AAAS)

1991 - Fellow of the American Academy of Arts and Sciences

1990 - Genetics Society of America Medal

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Genetics

Her primary areas of study are Genetics, Meiosis, Meiotic recombination checkpoint, Homologous recombination and Synaptonemal complex. Her biological study deals with issues like Cell biology, which deal with fields such as Recombination. Her study focuses on the intersection of Meiosis and fields such as Chromatin with connections in the field of Mitosis.

In her study, Holliday junction is inextricably linked to MSH4, which falls within the broad field of Meiotic recombination checkpoint. Her research investigates the link between Homologous recombination and topics such as Chiasma that cross with problems in Sister chromatids and Cohesin. Her work deals with themes such as Synapsis and Evolutionary biology, which intersect with Synaptonemal complex.

Her most cited work include:

  • Capturing Chromosome Conformation (2840 citations)
  • Improved single and multicopy lac-based cloning vectors for protein and operon fusions (1452 citations)
  • Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. (1417 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Genetics, Meiosis, Transposable element, Tn10 and DNA. Genetics is represented through her Insertion sequence, Homologous chromosome, Homologous recombination, Gene and Chromosome research. Her Meiosis research includes themes of Genetic recombination, Crossover and Cell biology.

Her studies deal with areas such as Plasmid and Cleavage as well as Transposable element. Nancy Kleckner works mostly in the field of Tn10, limiting it down to topics relating to Molecular biology and, in certain cases, Escherichia coli and DNA repair. Her work is dedicated to discovering how DNA, Biophysics are connected with Binding site and other disciplines.

She most often published in these fields:

  • Genetics (67.98%)
  • Meiosis (30.70%)
  • Transposable element (26.32%)

What were the highlights of her more recent work (between 2010-2021)?

  • Genetics (67.98%)
  • Meiosis (30.70%)
  • Crossover (6.58%)

In recent papers she was focusing on the following fields of study:

Nancy Kleckner focuses on Genetics, Meiosis, Crossover, Cell biology and Chromosome. Her study in Genetics focuses on Sister chromatids, Prophase, DNA, Saccharomyces cerevisiae and Point mutation. Her study in Meiosis is interdisciplinary in nature, drawing from both Homologous chromosome, Interference and Homologous recombination.

Her Cell biology study integrates concerns from other disciplines, such as Cell division, Operator, SUMO protein and Cell cycle, Mitotic cell cycle. Her Chromosome research is multidisciplinary, incorporating perspectives in Chromatin, Repressor and Nucleoid. She interconnects Synapsis, Spindle pole body and Fungal protein in the investigation of issues within Synaptonemal complex.

Between 2010 and 2021, her most popular works were:

  • Recombination, Pairing, and Synapsis of Homologs during Meiosis (394 citations)
  • Four-Dimensional Imaging of E. coli Nucleoid Organization and Dynamics in Living Cells (210 citations)
  • Topoisomerase II mediates meiotic crossover interference (116 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

Her main research concerns Genetics, Meiosis, Crossover, Interference and Homologous chromosome. Her Genetics research is multidisciplinary, incorporating elements of Evolutionary biology, Biophysics and Cell biology. Nancy Kleckner has included themes like Saccharomyces cerevisiae, Recombination and Homologous recombination in her Meiosis study.

Her research in Saccharomyces cerevisiae intersects with topics in RAD51, DMC1 and DNA repair. Nancy Kleckner has researched Interference in several fields, including Microtubule organizing center, Centromere and Chiasma. Her Chromosome study combines topics from a wide range of disciplines, such as Chromatin and Prophase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Capturing Chromosome Conformation

Job Dekker;Karsten Rippe;Martijn Dekker;Nancy Kleckner.
Science (2002)

3440 Citations

Improved single and multicopy lac-based cloning vectors for protein and operon fusions

R.W. Simons;F. Houman;N. Kleckner.
Gene (1987)

2126 Citations

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.

Scott Keeney;Craig N Giroux;Nancy Kleckner.
Cell (1997)

1660 Citations

Meiotic chromosomes: integrating structure and function.

D. Zickler;N. Kleckner.
Annual Review of Genetics (1999)

1611 Citations

DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression.

Douglas K. Bishop;Demian Park;Liuzhong Xu;Nancy Kleckner.
Cell (1992)

1552 Citations

A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains.

Eric Alani;Liang Cao;Nancy Kleckner.
Genetics (1987)

1058 Citations

The Single-End Invasion: An Asymmetric Intermediate at the Double-Strand Break to Double-Holliday Junction Transition of Meiotic Recombination

Neil Hunter;Nancy Kleckner.
Cell (2001)

861 Citations

Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis.

G.Valentin Börner;Nancy Kleckner;Neil Hunter;Neil Hunter.
Cell (2004)

851 Citations

Transposable elements in prokaryotes.

Nancy Kleckner.
Annual Review of Genetics (1981)

838 Citations

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

Eric Alani;Ruth Padmore;Nancy Kleckner.
Cell (1990)

763 Citations

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Best Scientists Citing Nancy Kleckner

Scott Keeney

Scott Keeney

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Job Dekker

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Romain Koszul

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Institut Pasteur

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Gerald R. Smith

Fred Hutchinson Cancer Research Center

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Josef Loidl

Josef Loidl

University of Vienna

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R. Scott Hawley

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Stowers Institute for Medical Research

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Patrick Sung

Patrick Sung

The University of Texas Health Science Center at San Antonio

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Akira Shinohara

Akira Shinohara

Osaka University

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Sergey V. Razin

Sergey V. Razin

Russian Academy of Sciences

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Wouter de Laat

Wouter de Laat

Utrecht University

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William S. Reznikoff

William S. Reznikoff

University of Wisconsin–Madison

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John R. Roth

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G. Shirleen Roeder

G. Shirleen Roeder

Yale University

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Anne M. Villeneuve

Anne M. Villeneuve

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Michael Lichten

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