His scientific interests lie mostly in Platelet, Immunology, Von Willebrand factor, Fibrinogen and Molecular biology. His work carried out in the field of Platelet brings together such families of science as Antibody, Monoclonal antibody and Fibrin. As a member of one scientific family, Heyu Ni mostly works in the field of Antibody, focusing on Immunotherapy and, on occasion, Platelet Glycoprotein GPIb-IX Complex and Autoantibody.
His Immunology research is multidisciplinary, incorporating perspectives in Thrombus, Internal medicine, Intravital microscopy and Endocrinology. His biological study spans a wide range of topics, including LDL receptor and Thrombopoietin. Heyu Ni has included themes like Hemostasis, Fibronectin and Integrin in his Fibrinogen study.
His primary areas of study are Platelet, Immunology, Antibody, Internal medicine and Platelet activation. His studies in Platelet integrate themes in fields like Hemostasis, Molecular biology, Integrin and Fibrinogen. Miscarriage, Platelet transfusion, Antibody titer and Isoantibodies is closely connected to Neonatal alloimmune thrombocytopenia in his research, which is encompassed under the umbrella topic of Immunology.
His Antibody research incorporates elements of Receptor and Platelet Glycoprotein GPIb-IX Complex. The study incorporates disciplines such as Gastroenterology and Endocrinology in addition to Internal medicine. His research investigates the link between Platelet activation and topics such as Pharmacology that cross with problems in P-selectin.
Heyu Ni spends much of his time researching Platelet, Immunology, Tantalum, Internal medicine and Hemostasis. His work deals with themes such as Megakaryopoiesis, Megakaryocyte, Ex vivo, Integrin and Cell biology, which intersect with Platelet. His study on Cell biology also encompasses disciplines like
His Internal medicine study incorporates themes from Gastroenterology and Endocrinology. His Endocrinology study also includes fields such as
Mesoporous material, Tantalum, Hemostasis, Immunology and Immune system are his primary areas of study. His studies deal with areas such as Antithrombotic, Signal transduction, Cell biology, Platelet activation and Intrauterine growth restriction as well as Hemostasis. The concepts of his Immunology study are interwoven with issues in Crosstalk and Neonatal alloimmune thrombocytopenia.
His Neonatal alloimmune thrombocytopenia research is multidisciplinary, relying on both Acquired immune system, Miscarriage, Platelet, Platelet transfusion and Placenta. The Platelet study combines topics in areas such as Coenzyme Q10 and Phosphorylation. His research integrates issues of Pathogenesis and Arthritis in his study of Immune system.
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Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
Heyu Ni;Cécile V. Denis;Sangeetha Subbarao;Jay L. Degen.
Journal of Clinical Investigation (2000)
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
Rukhsana Aslam;Edwin R. Speck;Michael Kim;Andrew R. Crow.
Plasma fibronectin promotes thrombus growth and stability in injured arterioles
Heyu Ni;Peter S. T. Yuen;Jessie M. Papalia;Jane E. Trevithick.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia
June Li;Dianne E. van der Wal;Guangheng Zhu;Miao Xu.
Nature Communications (2015)
Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond
Xiaohong Ruby Xu;Dan Zhang;Brigitta Elaine Oswald;Naadiya Carrim.
Critical Reviews in Clinical Laboratory Sciences (2016)
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice
Junmei Chen;Adili Reheman;Francisca C. Gushiken;Leticia Nolasco.
Journal of Clinical Investigation (2011)
Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα
Sanjeev Sethi;Ouliana Ziouzenkova;Heyu Ni;Denisa D. Wagner.
Platelets in hemostasis and thrombosis: role of integrins and their ligands.
Heyu Ni;John Freedman.
Transfusion and Apheresis Science (2003)
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
Leola Chow;Leola Chow;Rukhsana Aslam;Rukhsana Aslam;Edwin R. Speck;Edwin R. Speck;Michael Kim.
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis
Andrew J Murphy;Nora Bijl;Laurent Yvan-Charvet;Carrie B Welch.
Nature Medicine (2013)
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