D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 11,360 104 World Ranking 16048 National Ranking 6661

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Antibody

His scientific interests lie mostly in Molecular biology, Antigen, Antibody, In vivo and Mutant. His research in Molecular biology intersects with topics in HER2/neu, Pancreatic cancer, Monoclonal antibody and Epidermal growth factor receptor. His Antigen research integrates issues from Amino acid and Immunotoxin.

His studies in Antibody integrate themes in fields like Cancer cell, Nanoparticle and Internalization. His work on Biodistribution as part of general In vivo research is often related to Divalent, thus linking different fields of science. His studies deal with areas such as Complementarity determining region, Affinity maturation, Alanine, Receptor–ligand kinetics and Binding site as well as Mutant.

His most cited work include:

  • Monoclonal antibody therapy of cancer (1032 citations)
  • High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules. (526 citations)
  • Isolation of Picomolar Affinity Anti-c-erbB-2 Single-chain Fv by Molecular Evolution of the Complementarity Determining Regions in the Center of the Antibody Binding Site (512 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Antibody, Molecular biology, Cancer research, Antigen and Monoclonal antibody. His Antibody study is associated with Immunology. His work carried out in the field of Molecular biology brings together such families of science as In vivo, In vitro, Biodistribution, Biochemistry and Phage display.

His Cancer research study combines topics from a wide range of disciplines, such as Cancer cell, Cancer, Epidermal growth factor receptor, Secretion and Pathology. His Antigen study incorporates themes from Radioimmunotherapy, Immunotoxin, Mutant and Recombinant DNA. His study on Monoclonal antibody also encompasses disciplines like

  • Cytotoxic T cell which connect with Mechanism of action,
  • Virology together with Ratón.

He most often published in these fields:

  • Antibody (46.79%)
  • Molecular biology (36.70%)
  • Cancer research (26.61%)

What were the highlights of his more recent work (between 2013-2020)?

  • Antibody (46.79%)
  • Cancer research (26.61%)
  • Receptor (12.84%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Antibody, Cancer research, Receptor, Biophysics and Ribosome-inactivating protein. The various areas that Gregory P. Adams examines in his Antibody study include Biochemistry, Flow cytometry and Antigen. His research integrates issues of Cancer cell, Immunogenic cell death, Cytotoxic T cell, Epithelial cell adhesion molecule and Bone morphogenetic protein in his study of Cancer research.

His Receptor research includes elements of Prostate, Chimera, Apoptosis, Fallopian tube and Lung. His work investigates the relationship between Biophysics and topics such as Molecular imaging that intersect with problems in Molecular biology, Receptor expression, Tumor antigen and Binding site. The study incorporates disciplines such as Cancer stem cell, Antibody-drug conjugate, Drug resistance and In vivo in addition to Trastuzumab.

Between 2013 and 2020, his most popular works were:

  • Trastuzumab-deBouganin Conjugate Overcomes Multiple Mechanisms of T-DM1 Drug Resistance. (12 citations)
  • Molecular Simulation of Receptor Occupancy and Tumor Penetration of an Antibody and Smaller Scaffolds: Application to Molecular Imaging. (11 citations)
  • CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies (5 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Antibody

Gregory P. Adams mostly deals with Cancer research, Antibody, Ovarian cancer, Cancer cell and Immunotherapy. His biological study spans a wide range of topics, including Mechanism of action and Efflux, Biochemistry, Small molecule, Protein biosynthesis. His Antibody research includes themes of Biophysics, Tumor penetration, Molecular biology, Fusion protein and Cytotoxic T cell.

His study focuses on the intersection of Ovarian cancer and fields such as Endometrial cancer with connections in the field of Receptor. His Receptor study integrates concerns from other disciplines, such as Molecular imaging, Tumor antigen and Binding site. The concepts of his Cancer cell study are interwoven with issues in Ovarian tumor, Human leukocyte antigen and Flow cytometry, Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Monoclonal antibody therapy of cancer

Gregory P Adams;Louis M Weiner.
Nature Biotechnology (2005)

1707 Citations

High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules.

Gregory P. Adams;Robert Schier;Adrian M. McCall;Heidi H. Simmons.
Cancer Research (2001)

854 Citations

Isolation of Picomolar Affinity Anti-c-erbB-2 Single-chain Fv by Molecular Evolution of the Complementarity Determining Regions in the Center of the Antibody Binding Site

Robert Schier;Adrian McCall;Gregory P. Adams;Keith W. Marshall.
Journal of Molecular Biology (1996)

587 Citations

Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection.

Robert Schier;Jacqueline Bye;Gerald Apell;Adrian McCall.
Journal of Molecular Biology (1996)

500 Citations

Affinity and avidity in antibody-based tumor targeting.

Stephen I. Rudnick;Gregory P. Adams.
Cancer Biotherapy and Radiopharmaceuticals (2009)

425 Citations

Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging.

Lily Yang;Hui Mao;Y. Andrew Wang;Zehong Cao.
Small (2008)

416 Citations

Highly Specific in Vivo Tumor Targeting by Monovalent and Divalent Forms of 741F8 Anti-c-erbB-2 Single-Chain Fv

Gregory P. Adams;John E. McCartney;Mei-Sheng Tai;Hermann Oppermann.
Cancer Research (1993)

381 Citations

Increased Affinity Leads to Improved Selective Tumor Delivery of Single-Chain Fv Antibodies

Gregory P. Adams;Robert Schier;Keith Marshall;Ellen J. Wolf.
Cancer Research (1998)

376 Citations

Monoclonal antibody therapy for cancer.

Margaret von Mehren;Gregory P. Adams;Louis M. Weiner.
Annual Review of Medicine (2003)

369 Citations

Expression of Mutated Epidermal Growth Factor Receptor by Non-Small Cell Lung Carcinomas

I. E. Garcia De Palazzo;G. P. Adams;Padma Sundareshan;A. J. Wong.
Cancer Research (1993)

347 Citations

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