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Immunology

D-Index
52
Citations
10056
World Ranking
4056
National Ranking
1851

Overview

John F. Alcorn is affiliated with the Children's Hospital of Pittsburgh in the United States. Their research primarily focuses on medicine, with significant work in immunology and microbiology.

The main fields of study include:

  • Medicine
  • Immunology and Microbiology

The main subfields of study are:

  • Epidemiology
  • Immunology
  • Infectious Diseases
  • Pulmonary and Respiratory Medicine
  • Molecular Biology

The research topics covered extensively by John F. Alcorn include:

  • Influenza Virus Research Studies
  • Respiratory viral infections research
  • Immune Response and Inflammation
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Interferon and immune responses

Frequent collaborators in their work are:

  • Mary Patricia Nowalk
  • Richard K. Zimmerman
  • Danielle Antos
  • Brydie R. Huckestein
  • Judith M. Martin

John F. Alcorn has published frequently in the following venues:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Vaccine
  • PLoS ONE

Some recent papers authored or co-authored by John F. Alcorn include:

  • IL-22 Plays a Critical Role in Maintaining Epithelial Integrity During Pulmonary Infection (2020), Frontiers in Immunology
  • Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection (2020), Frontiers in Immunology
  • Influenza Suppresses Neutrophil Recruitment to the Lung and Exacerbates Secondary Invasive Pulmonary Aspergillosis (2020), The Journal of Immunology
  • Insights Into Type I and III Interferons in Asthma and Exacerbations (2020), Frontiers in Immunology
  • IFNγ-induction of TH1-like regulatory T cells controls antiviral responses (2023), Nature Immunology

Best Publications

  • TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

    Laura McKinley;John F. Alcorn;Alanna Peterson;Rachel B. DuPont

  • TH17 Cells in Asthma and COPD

    John F. Alcorn;Christopher R. Crowe;Jay K. Kolls

  • Critical Role of IL-17RA in Immunopathology of Influenza Infection

    Christopher R. Crowe;Kong Chen;Derek A. Pociask;John F. Alcorn

  • Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

    Anupa Kudva;Erich V. Scheller;Keven M. Robinson;Chris R. Crowe

  • Interleukin-17 Is Required for T Helper 1 Cell Immunity and Host Resistance to the Intracellular Pathogen Francisella tularensis

    Yinyao Lin;Shane Ritchea;Alison Logar;Samantha Slight

  • Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease

    Agnieszka Rynda-Apple;Keven M. Robinson;John F. Alcorn

  • Vitamin D and asthma.

    Grace Paul;John M. Brehm;John F. Alcorn;Fernando Holguín

  • IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection

    Derek A. Pociask;Erich V. Scheller;Sivanarayana Mandalapu;Kevin J. McHugh

  • Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity

    Kong Chen;Jeremy P. McAleer;Jeremy P. McAleer;Yuan Lin;David L. Paterson

  • Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis

    James L. Kreindler;Chad Steele;Nikki Nguyen;Yvonne R. Chan

  • IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

    Kong Chen;Derek A. Pociask;Jeremy P. McAleer;Yvonne R. Chan

  • Degradation of Pulmonary Surfactant Protein D by Pseudomonas aeruginosa Elastase Abrogates Innate Immune Function

    John F. Alcorn;Jo Rae Wright

  • The immunology of influenza virus-associated bacterial pneumonia.

    Keven M Robinson;Jay K Kolls;John F Alcorn

  • Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1β Production in Mice

    Keven M. Robinson;Sun Mi Choi;Kevin J. McHugh;Sivanarayana Mandalapu

  • Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-β1

    John F. Alcorn;Amy S. Guala;Jos van der Velden;Brian McElhinney

  • Transforming Growth Factor-β1 Suppresses Airway Hyperresponsiveness in Allergic Airway Disease

    John F. Alcorn;Lisa M. Rinaldi;Elizabeth F. Jaffe;Mirjam van Loon

  • Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina

    Rekha R. Rapaka;David M. Ricks;John F. Alcorn;Kong Chen

  • Influenza Induces Endoplasmic Reticulum Stress, Caspase-12–Dependent Apoptosis, and c-Jun N-Terminal Kinase–Mediated Transforming Growth Factor–β Release in Lung Epithelial Cells

    Elle C. Roberson;Jane E. Tully;Amy S. Guala;Jessica N. Reiss

  • Influenza A Virus Exacerbates Staphylococcus aureus Pneumonia in Mice by Attenuating Antimicrobial Peptide Production

    Keven M. Robinson;Kevin J. McHugh;Sivanarayana Mandalapu;Michelle E. Clay

  • Nuclear Factor-κB Activation in Airway Epithelium Induces Inflammation and Hyperresponsiveness

    Cristen Pantano;Jennifer L. Ather;John F. Alcorn;Matthew E. Poynter

  • Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells.

    Takako Nagata;Laura Mckinley;Jacques J. Peschon;John F. Alcorn

Frequent Co-Authors

Jay K. Kolls
Jay K. Kolls Tulane University
Yvonne M. W. Janssen-Heininger
Yvonne M. W. Janssen-Heininger University of Vermont
Erick Forno
Erick Forno University of Pittsburgh
Charles G. Irvin
Charles G. Irvin University of Vermont
Joseph M. Pilewski
Joseph M. Pilewski University of Pittsburgh
Richard K. Zimmerman
Richard K. Zimmerman University of Pittsburgh
Mary Patricia Nowalk
Mary Patricia Nowalk University of Pittsburgh
Shabaana A. Khader
Shabaana A. Khader Washington University in St. Louis
Matthew E. Poynter
Matthew E. Poynter University of Vermont
Javier Rangel-Moreno
Javier Rangel-Moreno University of Rochester

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