D-Index & Metrics Best Publications
Yoshiharu Machida

Yoshiharu Machida

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 40 Citations 6,318 167 World Ranking 12852 National Ranking 1071

Overview

What is he best known for?

The fields of study he is best known for:

  • Biochemistry
  • Organic chemistry
  • Enzyme

His primary areas of study are Dosage form, Chitosan, Chromatography, In vivo and Pharmacokinetics. His Dosage form research includes themes of Excipient, Intestinal absorption, Insulin, Liberation and Permeation. His Chitosan research is multidisciplinary, incorporating elements of Antibacterial agent, Surgery, Immunology and Polymer.

Many of his studies on Chromatography involve topics that are commonly interrelated, such as Bioavailability. Yoshiharu Machida has included themes like Oral administration, In vitro, Aqueous solution and Microparticle in his In vivo study. His study on Pharmacokinetics also encompasses disciplines like

  • Biochemistry and related Drug carrier and Fluorescein,
  • Excretion which is related to area like Incubation.

His most cited work include:

  • Biodegradation and distribution of water-soluble chitosan in mice. (371 citations)
  • Application of chitin and chitosan derivatives in the pharmaceutical field (218 citations)
  • New mucosal dosage form of insulin. (174 citations)

What are the main themes of his work throughout his whole career to date?

Chromatography, Dosage form, Pharmacology, Nuclear chemistry and In vivo are his primary areas of study. As a part of the same scientific family, Yoshiharu Machida mostly works in the field of Chromatography, focusing on Solubility and, on occasion, Stability constants of complexes and Dissolution. His biological study spans a wide range of topics, including Active ingredient, Excipient, Intestinal absorption, Stereochemistry and Drug carrier.

His work in Pharmacology addresses issues such as Mitomycin C, which are connected to fields such as Estrogen and Carbodiimide. His Nuclear chemistry research incorporates themes from Chitosan, Aqueous solution, Organic chemistry, Camptothecin and Nanoparticle. His In vivo research is multidisciplinary, relying on both Ketoprofen, In vitro and Drug delivery.

He most often published in these fields:

  • Chromatography (37.38%)
  • Dosage form (36.89%)
  • Pharmacology (24.27%)

What were the highlights of his more recent work (between 2006-2014)?

  • Chromatography (37.38%)
  • Nuclear chemistry (19.42%)
  • Dosage form (36.89%)

In recent papers he was focusing on the following fields of study:

His main research concerns Chromatography, Nuclear chemistry, Dosage form, In vivo and Pharmacology. The study incorporates disciplines such as Plasma concentration, Aqueous solution and Solubility in addition to Chromatography. Within one scientific family, Yoshiharu Machida focuses on topics pertaining to Microparticle under Nuclear chemistry, and may sometimes address concerns connected to Liberation, Chitosan and Enteric coating.

His work carried out in the field of Dosage form brings together such families of science as High-performance liquid chromatography, Oleic acid and Adsorption. His In vivo research includes elements of Immunology and Pathology. His Pharmacokinetics study incorporates themes from Absorption and Bioavailability.

Between 2006 and 2014, his most popular works were:

  • Novel chitosan wound dressing loaded with minocycline for the treatment of severe burn wounds. (128 citations)
  • Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin. (79 citations)
  • Novel preparation of enteric-coated chitosan-prednisolone conjugate microspheres and in vitro evaluation of their potential as a colonic delivery system. (39 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Biochemistry
  • Enzyme

His primary areas of investigation include In vivo, Chitosan, Liberation, Pharmacology and Dosage form. His In vivo research is multidisciplinary, incorporating perspectives in Nanoparticle, Stereochemistry, Immunology and Pathology. The Chitosan study combines topics in areas such as Antibacterial agent, Wound healing, Surgery, Lactoferrin and Carrageenan.

His studies in Liberation integrate themes in fields like Pharmacokinetics, Nuclear chemistry and Microparticle. His Nuclear chemistry research integrates issues from Camptothecin, Organic chemistry and In vitro. His Dosage form study combines topics from a wide range of disciplines, such as Bioadhesive, Oral mucosa, Stearic acid and Transdermal.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biodegradation and distribution of water-soluble chitosan in mice.

Hiraku Onishi;Yoshiharu Machida.
Biomaterials (1999)

566 Citations

Application of chitin and chitosan derivatives in the pharmaceutical field

Yoshinori Kato;Hiraku Onishi;Yoshiharu Machida.
Current Pharmaceutical Biotechnology (2003)

332 Citations

New mucosal dosage form of insulin.

Masami Ishida;Yoshiharu Machida;Naoki Nambu;Tsuneji Nagai.
Chemical & Pharmaceutical Bulletin (1981)

268 Citations

N-succinyl-chitosan as a drug carrier: water-insoluble and water-soluble conjugates

Yoshinori Kato;Hiraku Onishi;Yoshiharu Machida.
Biomaterials (2004)

221 Citations

Characteristics of polyion complexes of chitosan with sodium alginate and sodium polyacrylate

Toshiya Takahashi;Kozo Takayama;Yoshiharu Machida;Tsuneji Nagai.
International Journal of Pharmaceutics (1990)

208 Citations

Site-dependent effect of aprotinin, sodium caprate, Na2EDTA and sodium glycocholate on intestinal absorption of insulin

Mariko Morishita;Isao Morishita;Kozo Takayama;Yoshiharu Machida.
Biological & Pharmaceutical Bulletin (1993)

203 Citations

In vitro and in vivo nasal mucoadhesion of some water-soluble polymers

Fumihiko Nakamura;Ryoko Ohta;Yoshiharu Machida;Tsuneji Nagai.
International Journal of Pharmaceutics (1996)

201 Citations

Novel chitosan wound dressing loaded with minocycline for the treatment of severe burn wounds.

Shuichi Aoyagi;Hiraku Onishi;Yoshiharu Machida.
International Journal of Pharmaceutics (2007)

190 Citations

Hypoglycemic effect of novel oral microspheres of insulin with protease inhibitor in normal and diabetic rats

Isao Morishita;Mariko Morishita;Kozo Takayama;Yoshiharu Machida.
International Journal of Pharmaceutics (1992)

181 Citations

Effect of interpolymer complex formation on bioadhesive property and drug release phenomenon of compressed tablet consisting of chitosan and sodium hyaluronate.

Kozo Takayama;Meiko Hirata;Yoshiharu Machida;Tomoaki Masada.
Chemical & Pharmaceutical Bulletin (1990)

151 Citations

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