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Chemistry

D-Index
45
Citations
12071
World Ranking
16250
National Ranking
4050

Overview

Naír Rodríguez-Hornedo is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans materials science and chemistry, with significant emphasis on materials chemistry and physical and theoretical chemistry. They have also contributed to molecular biology, biomedical engineering, and spectroscopy.

The core topics in Rodríguez-Hornedo's work include crystallization and solubility studies, crystallography and molecular interactions, and phase equilibria and thermodynamics. Additional areas of investigation cover phenothiazines and benzothiazines synthesis and activities, electrohydrodynamics and fluid dynamics, mass spectrometry techniques and applications, and enzyme catalysis and immobilization.

Rodríguez-Hornedo has authored publications in several journals and has published multiple papers in prominent venues such as:

  • Crystal Growth & Design (3 publications)
  • Molecular Pharmaceutics (2 publications)
  • Journal of Controlled Release
  • European Journal of Pharmaceutical Sciences
  • Pharmaceutics

Among recent publications are:

  • "The role of pH and dose/solubility ratio on cocrystal dissolution, drug supersaturation and precipitation," 2020, European Journal of Pharmaceutical Sciences
  • "Cocrystal Solubility Advantage and Dose/Solubility Ratio Diagrams: A Mechanistic Approach To Selecting Additives and Controlling Dissolution-Supersaturation-Precipitation Behavior," 2020, Molecular Pharmaceutics
  • "Coaxial electrospray of uniform polylactide core-shell microparticles for long-acting contraceptive," 2021, Journal of Controlled Release
  • "Stability of Pharmaceutical Co-Crystals at Humid Conditions Can Be Predicted," 2021, Pharmaceutics
  • "Synchronization of Cocrystal Dissolution and Drug Precipitation to Sustain Drug Supersaturation," 2022, Molecular Pharmaceutics

Rodríguez-Hornedo frequently collaborates with researchers including Gislaine Kuminek, Max Shtein, Tatiane Cogo Machado, Simone Gonçalves Cardoso, and Katie L. Cavanagh, indicating a network of ongoing scientific partnerships.

Best Publications

  • Polymorphs, Salts, and Cocrystals: What’s in a Name?

    Srinivasulu Aitipamula;Rahul Banerjee;Arvind K. Bansal;Kumar Biradha

  • Solubility Advantage of Pharmaceutical Cocrystals

    David J. Good;Naír Rodríguez-Hornedo

  • Pharmaceutical cocrystals and poorly soluble drugs.

    Ranjit Thakuria;Amit Delori;William Jones;Maya P. Lipert

  • General principles of pharmaceutical solid polymorphism: a supramolecular perspective.

    Barbara Rodríguez-Spong;Christopher P Price;Adivaraha Jayasankar;Adam J Matzger

  • Crystal Engineering of the Composition of Pharmaceutical Phases: Multiple-Component Crystalline Solids Involving Carbamazepine

    Scott G. Fleischman;Srinivasan S. Kuduva;Jennifer A. McMahon;Brian Moulton

  • Significance of controlling crystallization mechanisms and kinetics in pharmaceutical systems

    Naír Rodríguez‐hornedo;Denette Murphy

  • Screening strategies based on solubility and solution composition generate pharmaceutically acceptable cocrystals of carbamazepine

    Scott L. Childs;Naír Rodríguez-Hornedo;L. Sreenivas Reddy;Adivaraha Jayasankar

  • Phase solubility diagrams of cocrystals are explained by solubility product and solution complexation

    Sarah J. Nehm;Barbara Rodríguez-Spong;Naír Rodríguez-Hornedo

  • Reaction crystallization of pharmaceutical molecular complexes.

    Naír Rodríguez-Hornedo;Sarah J. Nehm;Kurt F. Seefeldt;Yomaira Pagán-Torres

  • Crystal engineering of the composition of pharmaceutical phases

    R. D. Bailey Walsh;M. W. Bradner;S. Fleischman;L. A. Morales

  • Rheological Characterization of Topical Carbomer Gels Neutralized to Different pH

    Mohammad T. Islam;Naír Rodríguez-Hornedo;Susan Ciotti;Chrisita Ackermann

  • A rapid thermal method for cocrystal screening

    Enxian Lu;Naír Rodríguez-Hornedo;Raj Suryanarayanan

  • Cocrystal Formation during Cogrinding and Storage is Mediated by Amorphous Phase

    Adivaraha Jayasankar;Anongnat Somwangthanaroj;Anongnat Somwangthanaroj;Zezhi J. Shao;Naír Rodríguez-Hornedo

  • Protein Denaturation during Freezing and Thawing in Phosphate Buffer Systems: Monomeric and Tetrameric β-Galactosidase

    Katherine A. Pikal-Cleland;Naír Rodríguez-Hornedo;Gordon L. Amidon;John F. Carpenter

  • Cocrystals and Salts of Gabapentin: pH Dependent Cocrystal Stability and Solubility

    L. Sreenivas Reddy;Sarah J. Bethune;Jeff W. Kampf;Naír Rodríguez-Hornedo

  • Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5

    Gislaine Kuminek;Fengjuan Cao;Alanny Bahia de Oliveira da Rocha;Simone Gonçalves Cardoso

  • Crystallization pathways and kinetics of carbamazepine–nicotinamide cocrystals from the amorphous state by in situ thermomicroscopy, spectroscopy, and calorimetry studies

    K. Seefeldt;K. Seefeldt;J. Miller;F. Alvarez-Núñez;N. Rodríguez-Hornedo

  • Effect of initial buffer composition on pH changes during far-from-equilibrium freezing of sodium phosphate buffer solutions.

    Gerardo Gómez;Michael J Pikal;Naír Rodríguez-Hornedo

  • Role of Cocrystal and Solution Chemistry on the Formation and Stability of Cocrystals with Different Stoichiometry

    Adivaraha Jayasankar;L. Sreenivas Reddy;Sarah J. Bethune;Naír Rodríguez-Hornedo

  • Understanding and Predicting the Effect of Cocrystal Components and pH on Cocrystal Solubility

    Sarah J. Bethune;Neal Huang;Adivaraha Jayasankar;Naír Rodríguez-Hornedo

  • Solution-mediated phase transformation of anhydrous to dihydrate carbamazepine and the effect of lattice disorder.

    D Murphy;F Rodrı́guez-Cintrón;B Langevin;R.C Kelly

Frequent Co-Authors

Gordon L. Amidon
Gordon L. Amidon University of Michigan–Ann Arbor
Michael J. Zaworotko
Michael J. Zaworotko University of Limerick
Adam J. Matzger
Adam J. Matzger University of Michigan–Ann Arbor
Robin D. Rogers
Robin D. Rogers University of Alabama
Ayyalusamy Ramamoorthy
Ayyalusamy Ramamoorthy Florida State University
Rahul Banerjee
Rahul Banerjee Indian Institute of Science Education and Research Kolkata
Gabriele Sadowski
Gabriele Sadowski TU Dortmund University
Gautam R. Desiraju
Gautam R. Desiraju Indian Institute of Science
Changquan Calvin Sun
Changquan Calvin Sun University of Minnesota
Kumar Biradha
Kumar Biradha Indian Institute of Technology Kharagpur

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