World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
76
Citations
18147
World Ranking
18900
National Ranking
9418

Lawrence J. Lesko publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Lawrence J. Lesko sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 278 publications — 13th percentile

13% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Lawrence J. Lesko D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Lawrence J. Lesko sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 76 D-Index — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Lawrence J. Lesko is affiliated with the University of Florida in the United States and focuses primarily on medical research. Their scholarly work spans several interrelated fields including cardiology and cardiovascular medicine, pharmacology, economics and econometrics, pediatrics, perinatology and child health, as well as immunology. The research output in these areas totals over 33 publications, indicating a broad yet specialized engagement with key aspects of medicine.

The main topics that characterize Lesko's research activities include pharmacogenetics and drug metabolism, pharmaceutical studies and practices, statistical methods in clinical trials, biosimilars and bioanalytical methods, health systems, economic evaluations, and quality of life, computational drug discovery methods, and atrial fibrillation management and outcomes.

Lesko has contributed to a number of research papers published in well-recognized scientific venues. Notable publications include:

  • Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy, 2020, The Annual Review of Pharmacology and Toxicology
  • Study of pharmacogenomic information in FDA-approved drug labeling to facilitate application of precision medicine, 2020, Drug Discovery Today
  • Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function, 2020, JAMA Network Open
  • Perspective on model-informed drug development, 2021, CPT Pharmacometrics & Systems Pharmacology
  • A Review on Drug-Induced Nephrotoxicity: Pathophysiological Mechanisms, Drug Classes, Clinical Management, and Recent Advances in Mathematical Modeling and Simulation Approaches, 2020, Clinical Pharmacology in Drug Development

Frequent publication venues for Lesko include CPT Pharmacometrics & Systems Pharmacology, The Journal of Clinical Pharmacology, Clinical Pharmacology & Therapeutics, Clinical and Translational Science, and The Annual Review of Pharmacology and Toxicology.

Lesko maintains collaborative relationships with several recurring coauthors, including Mirjam N. Trame, Sarah Kim, Hardik Mody, Theodoros Soldatos, and Stephan Schmidt. These ongoing collaborations are reflected in multiple joint publications and research initiatives.

Best Publications

  • Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions

    Lawrence X. Yu;Gordon L. Amidon;James E. Polli;Hong Zhao

  • Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies.

    LJ Lesko;AJ Atkinson

  • Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review.

    P. Zhao;L. Zhang;J. A. Grillo;Q. Liu

  • Drug interaction studies: study design, data analysis, and implications for dosing and labeling.

    Huang Sm;Temple R;Throckmorton Dc;Lesko Lj

  • The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

    Zaiqi Wang;Zaiqi Wang;J. Christopher Gorski;J. Christopher Gorski;Mitchell A. Hamman;Mitchell A. Hamman;Shiew‐Mei Huang;Shiew‐Mei Huang

  • New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process

    Shiew Mei Huang;John M. Strong;Lei Zhang;Kellie S. Reynolds

  • Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology Models.

    Zhang Xy;Trame Mn;Lesko Lj;Schmidt S

  • Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues.

    Brian F. Gage;Lawrence J. Lesko

  • Pharmacogenomic Biomarker Information in Drug Labels Approved by the United States Food and Drug Administration: Prevalence of Related Drug Use

    Felix W. Frueh;Shashi Amur;Padmaja Mummaneni;Robert S. Epstein

  • Clinical pharmacokinetics and efficacy of amiodarone for refractory tachyarrhythmias.

    C I Haffajee;J C Love;A T Canada;L J Lesko

  • Medical applications of microarray technologies: a regulatory science perspective

    Emanuel F. Petricoin;Joseph L. Hackett;Lawrence J. Lesko;Raj K. Puri

  • Effect of St John's wort on the pharmacokinetics of fexofenadine.

    Zaiqi Wang;Mitchell A. Hamman;Shiew‐Mei Huang;Lawrence J. Lesko

  • Bioavailability and Bioequivalence: An FDA Regulatory Overview

    Mei-Ling Chen;Vinod Shah;Rabindra Patnaik;Wallace Adams

  • Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective.

    Lawrence J. Lesko;Janet Woodcock

  • Pharmacokinetic/pharmacodynamic modeling in drug research and development.

    Hartmut Derendorf;Lawrence J. Lesko;Philip Chaikin;Wayne A. Colburn

  • Personalized medicine: elusive dream or imminent reality?

    L J Lesko

  • Bioequivalence of Topical Dermatological Dosage Forms-Methods of Evaluation of Bioequivalence

    Vinod P. Shah;Gordon L. Flynn;Avraham Yacobi;Howard I. Maibach

  • Why has model-informed precision dosing not yet become common clinical reality?: Lessons from the past and a roadmap for the future

    A S Darwich;K Ogungbenro;A A Vinks;J R Powell

  • Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans.

    Lawrence J Lesko;Malcolm Rowland;Carl C Peck;Terrence F Blaschke

  • Medical applications of microarray technologies: a regulatory science perspective: a regulatory science perspective

    E. F. Petricoin;L. J. Lesko;J. L. Hackett

Frequent Co-Authors

Gordon L. Amidon
Gordon L. Amidon University of Michigan–Ann Arbor
Amin Rostami-Hodjegan
Amin Rostami-Hodjegan University of Manchester
Malcolm Rowland
Malcolm Rowland University of Manchester
Gordon L. Flynn
Gordon L. Flynn University of Michigan–Ann Arbor
Hans Lennernäs
Hans Lennernäs Uppsala University
Howard I. Maibach
Howard I. Maibach University of California, San Francisco
Mark J. Ratain
Mark J. Ratain University of Chicago
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore
Weida Tong
Weida Tong National Center for Toxicological Research
Mary V. Relling
Mary V. Relling St. Jude Children's Research Hospital

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