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Chemistry

D-Index
73
Citations
15280
World Ranking
5116
National Ranking
39

Overview

Anette Müllertz is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the field of Pharmacology, Toxicology and Pharmaceutics, with a significant focus on Pharmaceutical Science. Their work also intersects with Molecular Biology, Food Science, Materials Chemistry, and Biomedical Engineering.

The main topics addressed in Müllertz's research include:

  • Drug Solubility and Delivery Systems
  • Advanced Drug Delivery Systems
  • Crystallization and Solubility Studies
  • Analytical Chemistry and Chromatography
  • Gastrointestinal motility and disorders
  • Analytical Methods in Pharmaceuticals
  • Proteins in Food Systems

Their scholarly output includes numerous publications in recurrent journals such as:

  • International Journal of Pharmaceutics
  • European Journal of Pharmaceutics and Biopharmaceutics
  • Pharmaceutics
  • European Journal of Pharmaceutical Sciences
  • Journal of Drug Delivery Science and Technology

Frequent collaborators in their research include Thomas Rades, Ragna Berthelsen, Patrick Augustijns, Siriporn Okonogi, and Anja Boisen, reflecting collaborative efforts across various projects in the pharmaceutical sciences.

Some of the recent papers featuring Müllertz's work are:

  • Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review, 2020, European Journal of Pharmaceutical Sciences
  • Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network, 2021, Advanced Drug Delivery Reviews
  • Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability, 2021, European Journal of Pharmaceutics and Biopharmaceutics
  • INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies, 2021, Journal of Functional Foods
  • In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B, 2020, Pharmaceutics

Best Publications

  • In vitro models for the prediction of in vivo performance of oral dosage forms

    Edmund S. Kostewicz;Bertil Abrahamsson;Marcus Brewster;Joachim Brouwers

  • A dynamic in vitro lipolysis model: I. Controlling the rate of lipolysis by continuous addition of calcium

    Niels Hønberg Zangenberg;Anette Müllertz;Henning Gjelstrup Kristensen;Lars Hovgaard

  • Lipid-based formulations for oral administration of poorly water-soluble drugs.

    Huiling Mu;René Holm;René Holm;Anette Müllertz

  • Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

    Ben J. Boyd;Christel A.S. Bergström;Zahari Vinarov;Martin Kuentz

  • Toward the establishment of standardized in vitro tests for lipid‐based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations

    Hywel David Williams;Philip J Sassene;Karen Kleberg;Jean-Claude Bakala-N'Goma

  • New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs.

    Anette Müllertz;Anayo Ogbonna;Shan Ren;Thomas Rades

  • Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories.

    Rose Hayeshi;Constanze Hilgendorf;Per Artursson;Patrick Augustijns

  • A dynamic in vitro lipolysis model. II: Evaluation of the model.

    Niels Hønberg Zangenberg;Anette Müllertz;Henning Gjelstrup Kristensen;Lars Hovgaard

  • Bile salts and their importance for drug absorption.

    René Holm;Anette Müllertz;Huiling Mu

  • In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS).

    N. Thomas;R. Holm;A. Müllertz;T. Rades;T. Rades

  • Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols.

    Janne Ørskov Christensen;Kirsten Schultz;Birgitte Mollgaard;Henning Gjelstrup Kristensen

  • Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides.

    Rene Holm;Christopher John H Porter;Glenn A Edwards;Anette Mullertz

  • In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media

    Vibeke Hougaard Sunesen;Betty Lomstein Pedersen;Henning Gjelstrup Kristensen;Anette Müllertz

  • Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state.

    Flemming Seier Nielsen;Kamilla Buchberg Petersen;Anette Müllertz

  • Bioavailability of seocalcitol II: development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides.

    Mette Grove;Anette Müllertz;Jeanet Løgsted Nielsen;Gitte Pommergaard Pedersen

  • Morphological observations on a lipid-based drug delivery system during in vitro digestion.

    Dimitrios G. Fatouros;Bjorn Bergenstahl;Anette Mullertz

  • Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

    Hywel David Williams;Mette Uhre Anby;Philip J Sassene;Karen Kleberg

  • In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems.

    Anne T. Larsen;Philip Sassene;Anette Müllertz

  • A comparison of the solubility of danazol in human and simulated gastrointestinal fluids.

    Betty Lomstein Pedersen;Anette Müllertz;Helle Brøndsted;Henning Gjelstrup Kristensen

  • In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

    Ravi Devraj;Hywel David Williams;Dallas Warren;Anette Mullertz

  • Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies.

    Karen Kleberg;Jette Jacobsen;Anette Müllertz

Frequent Co-Authors

Thomas Rades
Thomas Rades University of Copenhagen
Anja Boisen
Anja Boisen Technical University of Denmark
Jukka Rantanen
Jukka Rantanen University of Copenhagen
Christopher J.H. Porter
Christopher J.H. Porter Monash University
Colin W. Pouton
Colin W. Pouton Monash University
Frédéric Carrière
Frédéric Carrière Aix-Marseille University
Hans Lennernäs
Hans Lennernäs Uppsala University
Björn Bergenståhl
Björn Bergenståhl Lund University
Lars Wågberg
Lars Wågberg Royal Institute of Technology

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