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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
13942
World Ranking
13670
National Ranking
133

Overview

Chaya Kalcheim is affiliated with the Hebrew University of Jerusalem in Israel and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research focus spans several subfields, predominantly molecular biology, developmental neuroscience, cellular and molecular neuroscience, surgery, and genetics.

The main topics of Kalcheim's work include developmental biology and gene regulation, hedgehog signaling pathway studies, neurogenesis and neuroplasticity mechanisms, axon guidance and neuronal signaling, Wnt/β-catenin signaling in development and cancer, single-cell and spatial transcriptomics, and cancer cells and metastasis.

Kalcheim has published numerous papers in various academic venues. Key recent publications include:

  • "Guidelines and definitions for research on epithelial-mesenchymal transition," 2020, Nature Reviews Molecular Cell Biology
  • "Neural tube development depends on notochord-derived Sonic hedgehog released into the sclerotome," 2020, Development
  • "Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition," 2021, Nature Reviews Molecular Cell Biology
  • "From Neural Crest to Definitive Roof Plate: The Dynamic Behavior of the Dorsal Neural Tube," 2021, International Journal of Molecular Sciences
  • "Completion of neural crest cell production and emigration is regulated by retinoic-acid-dependent inhibition of BMP signaling," 2022, eLife

The frequent coauthors collaborating with Kalcheim include Dina Rekler, Sarah Kagan, Shai Ofek, Gilgi Friedlander, and Nitza Kahane.

The main venues where Kalcheim's work has been published encompass Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), International Journal of Molecular Sciences, Nature Reviews Molecular Cell Biology, and Development.

Best Publications

  • The neural crest

    Nicole Le Douarin;Chaya Kalcheim

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins

    Yael Herzog;Chaya Kalcheim;Nitza Kahane;Ram Reshef

  • Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube.

    Dalit Sela-Donenfeld;Chaya Kalcheim

  • Formation of the dorsal root ganglia in the avian embryo: segmental origin and migratory behavior of neural crest progenitor cells.

    Marie-Aimée Teillet;Chaya Kalcheim;Nicole M. Le Douarin

  • Neurotrophin 3 is a mitogen for cultured neural crest cells.

    Chaya Kalcheim;Chana Carmeli;Arnon Rosenthal

  • Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination

    Irit Shoval;Andreas Ludwig;Chaya Kalcheim

  • Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition

    Tal Burstyn-Cohen;Jonathan Stanleigh;Dalit Sela-Donenfeld;Chaya Kalcheim

  • In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells.

    C. Kalcheim;Y. A. Barde;H. Thoenen;N. M. Le Douarin

  • Lineage analysis of the avian dermomyotome sheet reveals the existence of single cells with both dermal and muscle progenitor fates

    Raz Ben-Yair;Chaya Kalcheim

  • Evidence for a dynamic spatiotemporal fate map and early fate restrictions of premigratory avian neural crest.

    Shlomo Krispin;Erez Nitzan;Yachia Kassem;Chaya Kalcheim

  • Association between the cell cycle and neural crest delamination through specific regulation of G1/S transition.

    Tal Burstyn-Cohen;Chaya Kalcheim

  • Expression of basic fibroblast growth factor in the nervous system of early avian embryos

    C Kalcheim;G Neufeld

  • Inhibition of noggin expression in the dorsal neural tube by somitogenesis: a mechanism for coordinating the timing of neural crest emigration.

    Dalit Sela-Donenfeld;Chaya Kalcheim

  • F-Spondin, Expressed in Somite Regions Avoided by Neural Crest Cells, Mediates Inhibition of Distinct Somite Domains to Neural Crest Migration

    Anat Debby-Brafman;Tal Burstyn-Cohen;Avihu Klar;Chaya Kalcheim

  • Consequences of somite manipulation on the pattern of dorsal root ganglion development.

    C. Kalcheim;M.A. Teillet

  • The origin and fate of pioneer myotomal cells in the avian embryo.

    Nitza Kahane;Yuval Cinnamon;Chaya Kalcheim

  • The development of the chromaffin cell lineage from the neural crest

    Katrin Huber;Chaya Kalcheim;Klaus Unsicker

  • Requirement of a neural tube signal for the differentiation of neural crest cells into dorsal root ganglia

    C Kalcheim;N M Le Douarin

  • Gene expression pattern Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins

    Yael Herzog;Chaya Kalcheim;Nitza Kahane;Ram Reshef

Frequent Co-Authors

Klaus Unsicker
Klaus Unsicker University of Freiburg
Hermann Rohrer
Hermann Rohrer Goethe University Frankfurt
Günther Schütz
Günther Schütz German Cancer Research Center
Patricia A. Labosky
Patricia A. Labosky National Institutes of Health
Gera Neufeld
Gera Neufeld Technion – Israel Institute of Technology
Nicole M. Le Douarin
Nicole M. Le Douarin Collège de France
Alain Puisieux
Alain Puisieux Claude Bernard University Lyon 1
Rüdiger Klein
Rüdiger Klein Max Planck Society
Rhona Mirsky
Rhona Mirsky University College London
Pantelis Tsoulfas
Pantelis Tsoulfas University of Miami

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