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Kresten Lindorff-Larsen

Kresten Lindorff-Larsen

D-Index & Metrics

Chemistry

D-Index
70
Citations
31627
World Ranking
5729
National Ranking
46

Research.com Recognitions

  • 2009 - ACM Gordon Bell Prize Millisecond-Scale Molecular Dynamics Simulations on Anton

Overview

Kresten Lindorff-Larsen is affiliated with the University of Copenhagen in Denmark. Their research contributes extensively to the field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology, Materials Chemistry, Spectroscopy, Genetics, and Cell Biology.

Their work centers on topics that include:

  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Advanced NMR Techniques and Applications
  • Ubiquitin and proteasome pathways
  • RNA modifications and cancer

Lindorff-Larsen has published in a variety of notable venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Biophysical Journal
  • arXiv (Cornell University)
  • Nature Communications

Their recent papers include:

  • A structural biology community assessment of AlphaFold2 applications, 2022, Nature Structural & Molecular Biology
  • Accurate model of liquid-liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties, 2021, Proceedings of the National Academy of Sciences
  • Conformational ensembles of the human intrinsically disordered proteome, 2024, Nature
  • Integrating Molecular Simulation and Experimental Data: A Bayesian/Maximum Entropy Reweighting Approach, 2020, Methods in molecular biology
  • Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation, 2021, Nucleic Acids Research

Frequent co-authors collaborating with Lindorff-Larsen include:

  • Giulio Tesei
  • Rasmus Hartmann-Petersen
  • Amelie Stein
  • Kristoffer E. Johansson
  • F. Emil Thomasen

Among awards, Lindorff-Larsen received the ACM Gordon Bell Prize in 2009 with the citation "Millisecond-Scale Molecular Dynamics Simulations on Anton."

Best Publications

  • Improved side‐chain torsion potentials for the Amber ff99SB protein force field

    Kresten Lindorff-Larsen;Stefano Piana;Kim Palmo;Paul Maragakis

  • How Fast-Folding Proteins Fold

    Kresten Lindorff-Larsen;Stefano Piana;Ron O. Dror;David E. Shaw;David E. Shaw

  • Atomic-Level Characterization of the Structural Dynamics of Proteins

    David E. Shaw;David E. Shaw;Paul Maragakis;Kresten Lindorff-Larsen;Stefano Piana

  • Promoting transparency and reproducibility in enhanced molecular simulations

    M. Bonomi;M. Bonomi;B. Giovanni;C. Camilloni;G.A. Tribello

  • How robust are protein folding simulations with respect to force field parameterization

    Stefano Piana;Kresten Lindorff-Larsen;David E. Shaw;David E. Shaw

  • A structural biology community assessment of AlphaFold2 applications

    Unknown

  • Long-timescale molecular dynamics simulations of protein structure and function.

    John L Klepeis;Kresten Lindorff-Larsen;Ron O Dror;David E Shaw;David E Shaw

  • Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

    Matthew M. Dedmon;Kresten Lindorff-Larsen;John Christodoulou;Michele Vendruscolo

  • Simultaneous determination of protein structure and dynamics

    Kresten Lindorff-Larsen;Kresten Lindorff-Larsen;Robert B. Best;Robert B. Best;Mark A. DePristo;Mark A. DePristo;Christopher M. Dobson

  • Systematic validation of protein force fields against experimental data.

    Kresten Lindorff-Larsen;Paul Maragakis;Stefano Piana;Michael P. Eastwood

  • Millisecond-scale molecular dynamics simulations on Anton

    David E. Shaw;Ron O. Dror;John K. Salmon;J. P. Grossman

  • The Role of Protein Loops and Linkers in Conformational Dynamics and Allostery.

    Elena Papaleo;Giorgio Saladino;Matteo Lambrughi;Kresten Lindorff-Larsen

  • Accurate model of liquid-liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties.

    Giulio Tesei;Thea K Schulze;Ramon Crehuet;Ramon Crehuet;Kresten Lindorff-Larsen

  • Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.

    Jill J. Bouchard;Joel H. Otero;Daniel C. Scott;Elzbieta Szulc

  • Atomic-level description of ubiquitin folding

    Stefano Piana;Kresten Lindorff-Larsen;David E. Shaw;David E. Shaw

  • Principles of conduction and hydrophobic gating in K+ channels

    Morten Ø. Jensen;David W. Borhani;Kresten Lindorff-Larsen;Paul Maragakis

  • Protein folding kinetics and thermodynamics from atomistic simulation

    Stefano Piana;Kresten Lindorff-Larsen;David E. Shaw;David E. Shaw

  • Biophysical experiments and biomolecular simulations: A perfect match?

    Sandro Bottaro;Kresten Lindorff-Larsen

  • Structure and dynamics of an unfolded protein examined by molecular dynamics simulation.

    Kresten Lindorff-Larsen;Nikola Trbovic;Nikola Trbovic;Paul Maragakis;Stefano Piana

  • Microsecond Molecular Dynamics Simulation Shows Effect of Slow Loop Dynamics on Backbone Amide Order Parameters of Proteins

    Paul Maragakis;Kresten Lindorff-Larsen,‡,∇;Michael P. Eastwood;Ron O. Dror

  • Parallel protein-unfolding pathways revealed and mapped.

    Caroline F Wright;Kresten Lindorff-Larsen;Lucy G Randles;Jane Clarke

  • Millisecond-scale molecular dynamics simulations on Anton

    Unknown

Frequent Co-Authors

David E. Shaw
David E. Shaw D. E. Shaw Research
Yong Wang
Yong Wang Washington State University
Michele Vendruscolo
Michele Vendruscolo University of Cambridge
Birthe B. Kragelund
Birthe B. Kragelund University of Copenhagen
Robert B. Best
Robert B. Best National Institutes of Health
Christopher M. Dobson
Christopher M. Dobson University of Cambridge
Poul Nissen
Poul Nissen Aarhus University
Gregers R. Andersen
Gregers R. Andersen Aarhus University
Paul Schanda
Paul Schanda Institute of Science and Technology Austria

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