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Chemistry

D-Index
87
Citations
28918
World Ranking
2391
National Ranking
847

Research.com Recognitions

  • 1969 - Fellow of Alfred P. Sloan Foundation

Overview

Karl F. Freed is affiliated with the University of Chicago in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, alongside contributions in chemistry. The main topics of their work include protein structure and dynamics, mass spectrometry techniques and applications, advanced chemical physics studies, Alzheimer's disease research and treatments, enzyme structure and function, RNA and protein synthesis mechanisms, and supramolecular self-assembly in materials.

The scientist's recent publications encompass studies published between 2020 and 2022. Notable papers include:

  • "Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence," 2021, Journal of Chemical Theory and Computation
  • "Challenges and Advantages of Accounting for Backbone Flexibility in Prediction of Protein-Protein Complexes," 2022, Journal of Chemical Theory and Computation
  • "Molecular dynamics study of water channels in natural and synthetic amyloid-β fibrils," 2021, The Journal of Chemical Physics
  • "Water Dynamics and Interactions Inside Amyloid-Beta Fibrils," 2020, Biophysical Journal
  • "Upside: Protein Folding in CPU-Hours with Applications to Force-Unfolding of Membrane Proteins," 2020, Biophysical Journal

The frequent coauthors in their work include Tobin R. Sosnick, Xiangda Peng, Nabil F. Faruk, Joseph R. Sachleben, and Michael C. Baxa. Publication venues contributing most often to their body of work are the Biophysical Journal, Journal of Chemical Theory and Computation, and The Journal of Chemical Physics.

The scientist's research integrates multiple subfields such as molecular biology, spectroscopy, atomic and molecular physics and optics, physiology, and materials chemistry. Their studies contribute knowledge to areas including protein folding, enzyme function, and molecular interactions relevant to neurodegenerative conditions like Alzheimer's disease.

Karl F. Freed was recognized as a Fellow of the Alfred P. Sloan Foundation in 1969, highlighting a notable milestone in their academic career.

Best Publications

  • Renormalization Group Theory of Macromolecules

    Karl F. Freed

  • Multiphonon Processes in the Nonradiative Decay of Large Molecules

    Karl F. Freed;Joshua Jortner

  • Functional Integrals and Polymer Statistics

    Karl F. Freed

  • Characterization of branching architecture through "universal" ratios of polymer solution properties

    Jack F. Douglas;Jacques Roovers;Karl F. Freed

  • Statistical coil model of the unfolded state: Resolving the reconciliation problem

    Abhishek K. Jha;Andrés Colubri;Karl F. Freed;Tobin R. Sosnick

  • Effect of monomer structure and compressibility on the properties of multicomponent polymer blends and solutions: 1. Lattice cluster theory of compressible systems

    Jacek Dudowicz;Karl F. Freed

  • Energy dependence of electronic relaxation processes in polyatomic molecules

    K. F. Freed

  • Analysis and Evaluation of Ionization Potentials, Electron Affinities, and Excitation Energies by the Equations of Motion—Green's Function Method

    Michael F. Herman;Karl F. Freed;D. L. Yeager

  • Polymer viscosity in concentrated solutions

    Karl F. Freed;S. F. Edwards

  • Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water

    Joshua A. Riback;Micayla A. Bowman;Adam M. Zmyslowski;Catherine R. Knoverek

  • Generalized Entropy Theory of Polymer Glass Formation

    Jacek Dudowicz;Karl F. Freed;Jack F. Douglas

  • Intramolecular vibrational energy redistribution and the time evolution of molecular fluorescence

    Karl F. Freed;Abraham Nitzan

  • Dependence of Radiationless Decay Rates in Polyatomic Molecules upon the Initially Selected Vibronic State: General Theory and Application

    Donald F. Heller;Karl F. Freed;William M. Gelbart

  • Systematic corrections to Flory–Huggins theory: Polymer–solvent–void systems and binary blend–void systems

    M. G. Bawendi;Karl F. Freed

  • Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library.

    Abhishek K. Jha;Andres Colubri;Muhammad H. Zaman;Shohei Koide

  • The glass transition temperature of polymer melts.

    Jacek Dudowicz;Karl F Freed;Jack F Douglas

  • Theory of the dynamical viscosity of polymer solutions

    S. F. Edwards;Karl F. Freed

  • New lattice model for interacting, avoiding polymers with controlled length distribution

    K F Freed

  • Theory of the Hyperfine Structure of Molecules: Application to 3Π States of Diatomic Molecules Intermediate between Hund's Cases (a) and (b)

    Karl F. Freed

  • Role of molecular structure on the thermodynamic properties of melts, blends, and concentrated polymer solutions: comparison of Monte Carlo simulations with the cluster theory for the lattice model

    Jacek Dudowicz;Karl F. Freed;William G. Madden

  • Intramolecular perturbations and the quenching of luminescence in small molecules

    William M. Gelbart;Karl F. Freed

Frequent Co-Authors

Jack F. Douglas
Jack F. Douglas National Institute of Standards and Technology
Tobin R. Sosnick
Tobin R. Sosnick University of Chicago
Michael D. Morse
Michael D. Morse University of Utah
Igal Szleifer
Igal Szleifer Northwestern University
Shi-Qing Wang
Shi-Qing Wang University of Akron
Horia Metiu
Horia Metiu University of California, Santa Barbara
Stuart A. Rice
Stuart A. Rice University of Chicago
William M. Gelbart
William M. Gelbart University of California, Los Angeles
Sam F. Edwards
Sam F. Edwards University of Cambridge

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