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Chemistry

D-Index
59
Citations
12264
World Ranking
10149
National Ranking
2824

Overview

Jeffrey R. Deschamps is affiliated with the United States Naval Research Laboratory in the United States. Their research activity is concentrated primarily within the field of Materials Science, with a particular focus on Materials Chemistry. This specialization encompasses several subfields including Cellular and Molecular Neuroscience, Molecular Biology, Organic Chemistry, and Pharmacology.

The main topics covered in their work include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Pharmacological Receptor Mechanisms and Effects
  • Chemical Synthesis and Analysis

Deschamps has collaborated frequently with a core group of coauthors, among whom the most recurrent are Gregory H. Imler, Sumanta Garai, Luciana M. Leo, Anna-Maria Szczesniak, and Dow P. Hurst, indicating an extensive collaborative network in their research projects.

Their published work appears regularly in several scientific venues, with the most frequent publication outlets being:

  • The Cambridge Structural Database
  • Molecules
  • Journal of Medicinal Chemistry
  • ACS Omega
  • RSC Medicinal Chemistry

Key publications by Jeffrey R. Deschamps include:

  • "Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy" (2021, Journal of Medicinal Chemistry)
  • "G-Protein biased opioid agonists: 3-hydroxy-N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9" (2020, RSC Medicinal Chemistry)
  • "X-ray Crystallography and Unexpected Chiroptical Properties Reassign the Configuration of Haliclonadiamine" (2020, Journal of the American Chemical Society)
  • "Hydrochloride Salt of the GABAkine KRM-II-81" (2022, ACS Omega)
  • "Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines" (2022, Molecules)

Best Publications

  • Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors

    Ke Ding;Yipin Lu;Zaneta Nikolovska-Coleska;Su Qiu

  • A Hybrid Quantum Dot−Antibody Fragment Fluorescence Resonance Energy Transfer-Based TNT Sensor

    Ellen R. Goldman;Igor L. Medintz;Jessica L. Whitley;Andrew Hayhurst

  • Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates.

    Igor L. Medintz;Aaron R. Clapp;Florence M. Brunel;Theresa Tiefenbrunn

  • Analyzing nanomaterial bioconjugates: a review of current and emerging purification and characterization techniques.

    Kim E. Sapsford;Katherine M. Tyner;Benita J. Dair;Jeffrey R. Deschamps

  • 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors

    Peter C. Meltzer;David Butler;Jeffrey R. Deschamps;Bertha K. Madras

  • Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

    Joseph Tam;Resat Cinar;Jie Liu;Grzegorz Godlewski

  • Sensing Caspase 3 Activity with Quantum Dot-Fluorescent Protein Assemblies

    Kelly Boeneman;Bing C. Mei;Allison M. Dennis;Gang Bao

  • Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors.

    Yujun Zhao;Liu Liu;Wei Sun;Jianfeng Lu

  • Quantum dot DNA bioconjugates: attachment chemistry strongly influences the resulting composite architecture.

    Kelly Boeneman;Jeffrey R. Deschamps;Susan Buckhout-White;Duane E. Prasuhn

  • General Approach for the Synthesis of Sarpagine Indole Alkaloids. Enantiospecific Total Synthesis of (+)-Vellosimine, (+)-Normacusine B, (−)-Alkaloid Q3, (−)-Panarine, (+)-Na-Methylvellosimine, and (+)-Na-Methyl-16-epipericyclivine

    Jianming Yu;Tao Wang;Xiaoxiang Liu;Jeffrey Deschamps

  • Maltose-binding protein: a versatile platform for prototyping biosensing

    Igor L Medintz;Jeffrey R Deschamps

  • A Reagentless Biosensing Assembly Based on Quantum Dot–Donor Förster Resonance Energy Transfer

    Igor L. Medintz;Aaron R. Clapp;Joseph S. Melinger;Jeffrey R. Deschamps

  • Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging

    François Guérard;Yong-Sok Lee;Raphaël Tripier;Lawrence P. Szajek

  • Polyvalent Display and Packing of Peptides and Proteins on Semiconductor Quantum Dots: Predicted Versus Experimental Results

    Duane E. Prasuhn;Jeffrey R. Deschamps;Kimihiro Susumu;Michael H. Stewart

  • Proteolytic Activity at Quantum Dot-Conjugates: Kinetic Analysis Reveals Enhanced Enzyme Activity and Localized Interfacial “Hopping”

    W. Russ Algar;Anthony Malonoski;Jeffrey R. Deschamps;Juan B. Blanco-Canosa

  • Resonance Energy Transfer Between Luminescent Quantum Dots and Diverse Fluorescent Protein Acceptors.

    Igor L. Medintz;Thomas Pons;Kimihiro Susumu;Kelly Boeneman

  • Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials.

    Kelly Boeneman;James B. Delehanty;Juan B. Blanco-Canosa;Kimihiro Susumu

  • Monitoring botulinum neurotoxin a activity with peptide-functionalized quantum dot resonance energy transfer sensors

    Kim E Sapsford;Jessica Granek;Jeffrey R Deschamps;Kelly Boeneman

  • Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.

    Robert B. Laprairie;Pushkar M. Kulkarni;Jeffrey R. Deschamps;Melanie E. M. Kelly

  • PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

    Joseph E. Saavedra;Aloka Srinivasan;Gregory S. Buzard;Keith M. Davies

  • Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self‐Antigen Display

    Krystina L. Hess;Eunkeu Oh;Lisa H. Tostanoski;James I. Andorko

Frequent Co-Authors

Damon A. Parrish
Damon A. Parrish United States Naval Research Laboratory
Igor L. Medintz
Igor L. Medintz United States Naval Research Laboratory
Clifford George
Clifford George United States Naval Research Laboratory
Judith L. Flippen-Anderson
Judith L. Flippen-Anderson United States Naval Research Laboratory
Kimihiro Susumu
Kimihiro Susumu United States Naval Research Laboratory
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Arthur E. Jacobson
Arthur E. Jacobson National Institutes of Health
James M. Cook
James M. Cook University of Wisconsin–Milwaukee
Philip E. Dawson
Philip E. Dawson Scripps Research Institute
Hedi Mattoussi
Hedi Mattoussi Florida State University

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