World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
77
Citations
17228
World Ranking
4130
National Ranking
33

Biology and Biochemistry

D-Index
75
Citations
16413
World Ranking
5428
National Ranking
19

Overview

Shao Q. Yao is affiliated with the National University of Singapore in Singapore. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Organic Chemistry, Biomedical Engineering, Oncology, and Materials Chemistry.

Their work includes exploration of topics such as Click Chemistry and Applications, Protein Degradation and Inhibitors, Advanced biosensing and bioanalysis techniques, Nanoplatforms for cancer theranostics, RNA Interference and Gene Delivery, Peptidase Inhibition and Analysis, and Chemical Synthesis and Analysis.

Several recent papers highlight key areas of their research output:

  • "Mito-Bomb: Targeting Mitochondria for Cancer Therapy", 2021, published in Advanced Materials
  • "Smart Design of Nanomaterials for Mitochondria-Targeted Nanotherapeutics", 2020, published in Angewandte Chemie International Edition
  • "Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease", 2020, published in Chemical Society Reviews
  • "Recent advances in activity-based probes (ABPs) and affinity-based probes (AfBPs) for profiling of enzymes", 2021, published in Chemical Science
  • "The Dawn of a New Era: Targeting the "Undruggables" with Antibody-Based Therapeutics", 2023, published in Chemical Reviews

The frequent co-authors collaborating with Shao Q. Yao include:

  • Liqian Gao
  • Lin Li
  • Shubo Du
  • Jingyan Ge
  • Xiao Dong

Common publication venues for their work consist of:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Chemistry - A European Journal
  • Journal of the American Chemical Society
  • Chemical Communications

Best Publications

  • Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

    Zhengqiu Li;Piliang Hao;Lin Li;Chelsea Y. J. Tan

  • Mito-Bomb: Targeting Mitochondria for Cancer Therapy.

    Xiaolu Guo;Naidi Yang;Wenhui Ji;Hang Zhang

  • Functionalized xenon as a biosensor.

    Megan M. Spence;Seth M. Rubin;Ivan E. Dimitrov;E. Janette Ruiz

  • Developing photoactive affinity probes for proteomic profiling: hydroxamate-based probes for metalloproteases.

    Elaine W S Chan;Souvik Chattopadhaya;Resmi C Panicker;Xuan Huang

  • Smart Design of Nanomaterials for Mitochondria-Targeted Nanotherapeutics.

    Si Si Liew;Xiaofei Qin;Jia Zhou;Lin Li

  • Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities

    Peng Yu Yang;Kai Liu;Mun Hong Ngai;Martin James Lear

  • Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes.

    Haibin Shi;Chong-Jing Zhang;Grace Y. J. Chen;Shao Q. Yao

  • Rational Design of Nanocarriers for Intracellular Protein Delivery.

    Xiaofei Qin;Changmin Yu;Jing Wei;Lin Li

  • Intein-mediated biotinylation of proteins and its application in a protein microarray.

    Marie-Laure Lesaicherre;Rina Y. P. Lue;Grace Y. J. Chen;Qing Zhu

  • Selective amplification by auto- and cross-catalysis in a replicating peptide system

    Shao Yao;Indraneel Ghosh;Reena Zutshi;Jean Chmielewski

  • A minimalist fluorescent probe for differentiating Cys, Hcy and GSH in live cells

    Huatang Zhang;Ruochuan Liu;Jie Liu;Lin Li

  • Tetrazole Photoclick Chemistry: Reinvestigating Its Suitability as a Bioorthogonal Reaction and Potential Applications

    Zhengqiu Li;Zhengqiu Li;Linghui Qian;Lin Li;Jan C. Bernhammer

  • A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models

    Lin Li;Cheng-Wu Zhang;Grace Y. J. Chen;Biwei Zhu

  • Intracellular Delivery of Functional Proteins and Native Drugs by Cell-Penetrating Poly(disulfide)s

    Jiaqi Fu;Changmin Yu;Lin Li;Lin Li;Shao Q. Yao

  • Developing site-specific immobilization strategies of peptides in a microarray.

    Marie Laure Lesaicherre;Mahesh Uttamchandani;Grace Y J Chen;Shao Q Yao

  • Bypassing Endocytosis: Direct Cytosolic Delivery of Proteins

    Shubo Du;Si Si Liew;Lin Li;Shao Q. Yao

  • Gold nanorods as dual photo-sensitizing and imaging agents for two-photon photodynamic therapy.

    Tingting Zhao;Xiaoqin Shen;Lin Li;Zhenping Guan

  • SDS capillary gel electrophoresis of proteins in microfabricated channels

    Shao Yao;D. S. Anex;W. B. Caldwell;D. W. Arnold

  • "Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.

    Zhengqiu Li;Danyang Wang;Lin Li;Sijun Pan

  • Recent advances in activity-based probes (ABPs) and affinity-based probes (AfBPs) for profiling of enzymes.

    Haixiao Fang;Bo Peng;Sing Yee Ong;Qiong Wu

  • Small molecule microarrays: recent advances and applications

    Mahesh Uttamchandani;Daniel P Walsh;Shao Q Yao;Young-Tae Chang

Frequent Co-Authors

Qing-Hua Xu
Qing-Hua Xu National University of Singapore
Wei Huang
Wei Huang Northwestern Polytechnical University
John Paul Pezacki
John Paul Pezacki University of Ottawa
Siu Kwan Sze
Siu Kwan Sze Nanyang Technological University
Markus R. Wenk
Markus R. Wenk Hamad bin Khalifa University
Kah-Leong Lim
Kah-Leong Lim Nanyang Technological University
Young-Tae Chang
Young-Tae Chang Pohang University of Science and Technology
Guo Qin Xu
Guo Qin Xu National University of Singapore
Han-Ming Shen
Han-Ming Shen University of Macau
Min Wang
Min Wang University of Hong Kong

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