World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
15621
World Ranking
7461
National Ranking
26

Overview

Siu Kwan Sze is affiliated with Nanyang Technological University in Singapore and has a substantial body of research contributions primarily in biochemistry, genetics, and molecular biology. Their work spans a wide range of topics associated with molecular mechanisms in disease and cellular functions.

The main fields of study are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The subfields of study reflect a focus on molecular and cellular research relevant to health and disease:

  • Molecular Biology
  • Immunology
  • Cancer Research
  • Cardiology and Cardiovascular Medicine
  • Oncology

Research topics covered in their publications include:

  • Extracellular vesicles in disease
  • Cell Adhesion Molecules Research
  • RNA Research and Splicing
  • Protease and Inhibitor Mechanisms
  • RNA modifications and cancer
  • MicroRNA in disease regulation
  • Advanced Proteomics Techniques and Applications

Siu Kwan Sze has published in several notable venues, with some journals featuring multiple papers:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • ACS Omega
  • Scientific Reports
  • Nature

Their recent notable papers include:

  • Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis, 2021, Molecular Cell
  • Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles, 2020, Alzheimer s Research & Therapy
  • Vimentin protects differentiating stem cells from stress, 2020, Scientific Reports
  • Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated Disorders, 2020, Aging and Disease
  • Serum albumin cysteine trioxidation is a potential oxidative stress biomarker of type 2 diabetes mellitus, 2020, Scientific Reports

Collaborative research is indicated by frequent co-authorship with several researchers in related fields. Key co-authors of Siu Kwan Sze include:

  • SoFong Cam Ngan
  • Neil E. McCarthy
  • Jung Eun Park
  • Raj N. Kalaria
  • Evangelia Tsiani

The pattern of publications and collaborations suggests sustained involvement in research on molecular biology and disease processes, contributing to understanding mechanisms underlying cancer, neurodegenerative diseases, diabetes, and cell stress responses.

Best Publications

  • Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

    Jung Eun Park;Hon Sen Tan;Arnab Datta;Ruenn Chai Lai

  • Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome

    Ruenn Chai Lai;Soon Sim Tan;Bao Ju Teh;Siu Kwan Sze

  • Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

    Zhengqiu Li;Piliang Hao;Lin Li;Chelsea Y. J. Tan

  • Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells.

    Qiang Wu;Xi Chen;Xi Chen;Jinqiu Zhang;Yuin-Han Loh;Yuin-Han Loh

  • Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue.

    Siu Kwan Sze;Ying Ge;HanBin Oh;Fred W. McLafferty

  • Elucidating the Secretion Proteome of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells

    Siu Kwan Sze;Dominique P.V. de Kleijn;Ruenn Chai Lai;Eileen Khia Way Tan

  • CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex

    Yuk Kwan Choi;Pengfei Liu;Siu Kwan Sze;Chao Dai

  • Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy.

    HanBin Oh;Kathrin Breuker;Siu Kwan Sze;Ying Ge

  • Raman spectroscopic characterization of carbonaceous aerosols

    S.-K. Sze;N. Siddique;J.J. Sloan;R. Escribano

  • Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift

    Jung Eun Park;Bamaprasad Dutta;Shun Wilford Tse;Nikhil Gupta

  • MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA.

    Ruenn Chai Lai;Soon Sim Tan;Ronne Wee Yeh Yeo;Andre Boon Hwa Choo

  • Quantitative Time-course Profiling of Parasite and Host Cell Proteins in the Human Malaria Parasite Plasmodium falciparum

    Bernardo Javier Foth;Neng Zhang;Balbir Kaur Chaal;Siu Kwan Sze

  • The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

    Merry Gunawan;Nandini Venkatesan;Jia Tong Loh;Jong Fu Wong

  • Quantitative Secretomic Analysis of Trichoderma reesei Strains Reveals Enzymatic Composition for Lignocellulosic Biomass Degradation

    Sunil S. Adav;Lim Tze Chao;Siu Kwan Sze

  • Detection, Evaluation and Minimization of Nonenzymatic Deamidation in Proteomic Sample Preparation

    Piliang Hao;Yan Ren;Andrew J. Alpert;Siu Kwan Sze

  • PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy

    Liming Wang;Yik-Lam Cho;Yancheng Tang;Jigang Wang

  • Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing.

    Yan Yih Goh;Mintu Pal;Han Chung Chong;Pengcheng Zhu

  • Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

    Song Lin Chua;Joey Kuok Hoong Yam;Piliang Hao;Sunil S. Adav

  • Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events.

    Wouter Peeters;Dominique P.V. de Kleijn;Aryan Vink;Sander van de Weg

  • Nanosecond laser-induced photochemical oxidation method for protein surface mapping with mass spectrometry.

    Thin Thin Aye;Teck Yew Low;Siu Kwan Sze

Frequent Co-Authors

Sai Kiang Lim
Sai Kiang Lim Agency for Science, Technology and Research
James P. Tam
James P. Tam Nanyang Technological University
Christopher Chen
Christopher Chen National University of Singapore
Peter R. Preiser
Peter R. Preiser Nanyang Technological University
Artur Schmidtchen
Artur Schmidtchen Lund University
Raj N. Kalaria
Raj N. Kalaria Newcastle University
Eran Meshorer
Eran Meshorer Hebrew University of Jerusalem
Gerard Pasterkamp
Gerard Pasterkamp Utrecht University
Julien Lescar
Julien Lescar Nanyang Technological University
Mitchell K.P. Lai
Mitchell K.P. Lai National University of Singapore

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