World's Best Scientists 2026 revealed!
Han-Ming Shen

Han-Ming Shen

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Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
107
Citations
61425
World Ranking
1074
National Ranking
21

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award

Overview

Han-Ming Shen is affiliated with the University of Macau in China and has an extensive research portfolio focusing on Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work spans multiple subfields including Molecular Biology, Epidemiology, Physiology, Cancer Research, and Immunology.

The primary topics of Han-Ming Shen's research include:

  • Autophagy in Disease and Therapy
  • Calcium signaling and nucleotide metabolism
  • RNA modifications and cancer
  • Endoplasmic Reticulum Stress and Disease
  • Epigenetics and DNA Methylation
  • Mitochondrial Function and Pathology
  • Sirtuins and Resveratrol in Medicine

Han-Ming Shen has published frequently in several academic venues. Some of the most common publication outlets include:

  • Autophagy
  • International Journal of Biological Sciences
  • Nature Communications
  • Life Metabolism
  • Acta Pharmaceutica Sinica B

The scientist's recent papers reflect a focus on molecular mechanisms and therapeutic strategies related to autophagy, mitochondria, and disease intervention. Selected recent works include:

  • "Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19" (2020), International Journal of Biological Sciences
  • "Mito-Bomb: Targeting Mitochondria for Cancer Therapy" (2021), Advanced Materials
  • "The emerging mechanisms and functions of microautophagy" (2022), Nature Reviews Molecular Cell Biology
  • "Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1" (2021), Acta Pharmaceutica Sinica B
  • "Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow" (2022), Nature Biomedical Engineering

Han-Ming Shen collaborates frequently with a core group of co-authors, which include:

  • Guang Lu
  • Liming Wang
  • Dajing Xia
  • Jiahong Lu
  • Jing Zhou

This profile highlights a research career deeply embedded in molecular and cellular biology approaches to understanding disease, with a substantial output in peer-reviewed scientific literature and collaborations across related disciplines.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Luteolin, a flavonoid with potential for cancer prevention and therapy.

    Yong Lin;Ranxin Shi;Xia Wang;Han-Ming Shen

  • Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

    You-Tong Wu;Hui-Ling Tan;Guanghou Shui;Chantal Bauvy

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species

    Han-Ming Shen;Zheng-gang Liu

  • Anti-cancer properties of anthraquinones from rhubarb.

    Qing Huang;Guodong Lu;Han-Ming Shen;Maxey C.M. Chung

  • Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

    Jigang Wang;Chong-Jing Zhang;Wan Ni Chia;Cheryl C. Y. Loh

  • Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells

    Siyuan Zhang;Choon-Nam Ong;Han-Ming Shen

  • Dual role of autophagy in hallmarks of cancer.

    Shikha Satendra Singh;Somya Vats;Amelia Yi-Qian Chia;Tuan Zea Tan

  • Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms.

    Siyuan Zhang;Yen-Kim Won;Choon-Nam Ong;Han-Ming Shen

  • Tumor Necrosis Factor-induced Nonapoptotic Cell Death Requires Receptor-interacting Protein-mediated Cellular Reactive Oxygen Species Accumulation

    Yong Lin;Swati Choksi;Han-Ming Shen;Qing-Feng Yang

  • Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

    Zhengqiu Li;Piliang Hao;Lin Li;Chelsea Y. J. Tan

  • Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19.

    Naidi Yang;Han-Ming Shen

  • Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion

    Jing Zhou;Shi-Hao Tan;Valérie Nicolas;Chantal Bauvy

  • Autophagic cell death: Loch Ness monster or endangered species?

    Han-Ming Shen;Patrice Codogno

  • DETECTION OF ELEVATED REACTIVE OXYGEN SPECIES LEVEL IN CULTURED RAT HEPATOCYTES TREATED WITH AFLATOXIN B1

    Han-Ming Shen;Chen-Yang Shi;Yi Shen;Choon-Nam Ong

  • At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

    Han-Ming Shen;Noboru Mizushima

  • Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility

    Han-Ming Shen;Choon-Nam Ong

Frequent Co-Authors

Qingsong Lin
Qingsong Lin National University of Singapore
Wen-Xing Ding
Wen-Xing Ding University of Kansas
Boon-Huat Bay
Boon-Huat Bay National University of Singapore
Kah-Leong Lim
Kah-Leong Lim Nanyang Technological University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Sergio Lavandero
Sergio Lavandero University of Chile
Patrice Codogno
Patrice Codogno Université Paris Cité
Evelina Gatti
Evelina Gatti Aix-Marseille University
Zi-Chun Hua
Zi-Chun Hua Nanjing University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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