World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
11481
World Ranking
16066
National Ranking
458

Overview

Zi-Chun Hua is affiliated with Nanjing University in China and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans over 100 publications, predominantly focused on molecular biology, immunology, biomedical engineering, oncology, and biotechnology.

The main topics covered in their research include:

  • Cancer research and treatments
  • Nanoplatforms for cancer theranostics
  • Gut microbiota and health
  • Ferroptosis and cancer prognosis
  • Trace elements in health
  • Ubiquitin and proteasome pathways
  • Immunotherapy and immune responses

Zi-Chun Hua has published frequently in several scientific journals, with multiple contributions in the following venues:

  • Journal of Trace Elements in Medicine and Biology
  • Signal Transduction and Targeted Therapy
  • Advanced Science
  • Acta Pharmacologica Sinica
  • Frontiers in Pharmacology

The scientist's recent significant papers include:

  • Lasso Peptides: Heterologous Production and Potential Medical Application, 2020, Frontiers in Bioengineering and Biotechnology
  • SQR mediates therapeutic effects of H 2 S by targeting mitochondrial electron transport to induce mitochondrial uncoupling, 2020, Science Advances
  • Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment, 2021, Acta Pharmaceutica Sinica B
  • Bacterially mediated drug delivery and therapeutics: Strategies and advancements, 2022, Advanced Drug Delivery Reviews
  • Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer, 2021, Journal of Trace Elements in Medicine and Biology

Collaboration forms an important part of Zi-Chun Hua's research activity. Frequent coauthors include:

  • Hongqin Zhuang
  • Bo Zhu
  • Leyang Wu
  • Xingpeng Yin
  • Fangfang Cai

Best Publications

  • Apoptosis and apoptotic body: disease message and therapeutic target potentials.

    Xuebo Xu;Yueyang Lai;Zi-Chun Hua

  • Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

    Jigang Wang;Chong-Jing Zhang;Wan Ni Chia;Cheryl C. Y. Loh

  • The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism

    Xu-Kun Deng;Wu Yin;Wei-Dong Li;Fang-Zhou Yin

  • Galactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting.

    Shuying Gao;Jiangning Chen;Xuerong Xu;Zhi Ding

  • IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation

    Min Yang;Min Yang;Jun Deng;Yang Liu;King-Hung Ko

  • A simple copper(II)-L-histidine system for efficient hydrolytic cleavage of DNA.

    Rui Ren;Pin Yang;Weijuan Zheng;Zichun Hua

  • Use of 16S rRNA Gene-Targeted Group-Specific Primers for Real-Time PCR Analysis of Predominant Bacteria in Mouse Feces

    Yun-Wen Yang;Mang-Kun Chen;Bing-Ya Yang;Xian-Jie Huang

  • Analysis of microcystins in cyanobacteria blooms and surface water samples from Meiliang Bay, Taihu Lake, China

    P.P Shen;Q Shi;Z.C Hua;F.X Kong

  • Induction of Apoptosis in Mouse Liver by Microcystin-LR A Combined Transcriptomic, Proteomic, And Simulation Strategy

    Ting Chen;Qingsong Wang;Jun Cui;Wei Yang

  • Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs

    Zhiyuan Niu;Qian Shi;Wenlong Zhang;Yuxin Shu

  • A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region.

    Zi Chun Hua;Zi Chun Hua;Sue J Sohn;Chulho Kang;Dragana Cado

  • Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway.

    Zhongping Fu;Zhongping Fu;Xiao Chen;Shengwen Guan;Yanju Yan

  • The CpxR/CpxA two-component regulatory system up-regulates the multidrug resistance cascade to facilitate Escherichia coli resistance to a model antimicrobial peptide.

    Natasha Weatherspoon-Griffin;Dezhi Yang;Wei Kong;Zichun Hua

  • Target identification of natural and traditional medicines with quantitative chemical proteomics approaches.

    Jigang Wang;Jigang Wang;Liqian Gao;Yew Mun Lee;Karunakaran A. Kalesh

  • Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.

    Minghui Chen;Xueshi Wang;Daolong Zha;Fangfang Cai

  • Protective Effect of Procyanidin B2 against CCl4-Induced Acute Liver Injury in Mice

    Bing-Ya Yang;Xiang-Yu Zhang;Sheng-Wen Guan;Zi-Chun Hua

  • Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response

    Jun Deng;Yang Liu;Min Yang;Min Yang;Shengjun Wang

  • Thioredoxin glutathione reductase as a novel drug target: evidence from Schistosoma japonicum.

    LiJun Song;JiaHuang Li;ShuYing Xie;ChunYan Qian

  • Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity

    Jigang Wang;Jianbin Zhang;Yin Shi;Chengchao Xu

  • In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line

    Jigang Wang;Jigang Wang;Jigang Wang;Jianbin Zhang;Chong-Jing Zhang;Yin Kwan Wong

Frequent Co-Authors

Wei Dong
Wei Dong Nanjing University of Science and Technology
Qingsong Lin
Qingsong Lin National University of Singapore
Han-Ming Shen
Han-Ming Shen University of Macau
Liwei Lu
Liwei Lu University of Hong Kong
Shengjun Wang
Shengjun Wang Jiangsu University
Yang Sun
Yang Sun Nanjing University
Renxiang Tan
Renxiang Tan Nanjing University
Yayi Hou
Yayi Hou Nanjing University
Ning Gu
Ning Gu Southeast University
Bin Liu
Bin Liu National University of Singapore

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