Dmitry B. Veprintsev

Overview

Best Publications

• Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

  Frank M. Boeckler;Andreas C. Joerger;Gaurav Jaggi;Trevor J. Rutherford

  426
  Citations

• Universal allosteric mechanism for Gα activation by GPCRs

  Tilman Flock;Charles N. J. Ravarani;Dawei Sun;Dawei Sun;A. J. Venkatakrishnan

  385
  Citations

• Structures of SAS-6 Suggest Its Organization in Centrioles

  Mark van Breugel;Masafumi Hirono;Antonina Andreeva;Haru-aki Yanagisawa

  366
  Citations

• Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

  G. Elif Karagöz;G. Elif Karagöz;Afonso M.S. Duarte;Afonso M.S. Duarte;Elias Akoury;Hans Ippel;Hans Ippel

  359
  Citations

• A peptide that binds and stabilizes p53 core domain: Chaperone strategy for rescue of oncogenic mutants

  Assaf Friedler;Lars O. Hansson;Dmitry B. Veprintsev;Stefan M. V. Freund

  345
  Citations

• Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

  A. J. Venkatakrishnan;Xavier Deupi;Guillaume Lebon;Guillaume Lebon;Guillaume Lebon;Franziska M. Heydenreich;Franziska M. Heydenreich;Franziska M. Heydenreich

  316
  Citations

• Cooperative binding of tetrameric p53 to DNA.

  Richard L. Weinberg;Dmitry B. Veprintsev;Alan R. Fersht

  301
  Citations

• ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes

  Hsiangling Teo;David J. Gill;Ji Sun;Olga Perisic

  292
  Citations

• Comparative binding of p53 to its promoter and DNA recognition elements.

  Richard L. Weinberg;Dmitry B. Veprintsev;Mark Bycroft;Alan R. Fersht

  241
  Citations

• Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium.

  Zvi Hayouka;Joseph Rosenbluh;Aviad Levin;Shoshana Loya

  235
  Citations

• Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

  Maria Rosario Fernandez-Fernandez;Dmitry B. Veprintsev;Alan R. Fersht

  234
  Citations

• Structures of p53 Cancer Mutants and Mechanism of Rescue by Second-site Suppressor Mutations

  Andreas C. Joerger;Hwee Ching Ang;Dmitry B. Veprintsev;Caroline M. Blair

  205
  Citations

• The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

  Sebastian Eustermann;Hortense Videler;Ji-Chun Yang;Paul T. Cole

  204
  Citations

• Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

  Shin Isogai;Xavier Deupi;Christian Opitz;Franziska M. Heydenreich

  200
  Citations

• GPCR activation mechanisms across classes and macro/microscales.

  Alexander S Hauser;Albert J Kooistra;Christian Munk;Christian Munk;Franziska M Heydenreich

  177
  Citations

• Kinetic Instability of p53 Core Domain Mutants IMPLICATIONS FOR RESCUE BY SMALL MOLECULES

  Assaf Friedler;Dmitry B. Veprintsev;Lars O. Hansson;Alan R. Fersht

  174
  Citations

• Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

  Sara Ghazi-Tabatabai;Suraj Saksena;Judith M. Short;Ajaybabu V. Pobbati

  167
  Citations

• The central region of HDM2 provides a second binding site for p53

  Grace W. Yu;Stefan Rudiger;Dmitry Veprintsev;Stefan Freund

  166
  Citations

• Structural evolution of p53, p63, and p73: implication for heterotetramer formation.

  Andreas C. Joerger;Sridharan Rajagopalan;Eviatar Natan;Dmitry B. Veprintsev

  165
  Citations

• Structural insight into the ESCRT-I/-II link and its role in MVB trafficking.

  David J Gill;Hsiangling Teo;Ji Sun;Olga Perisic

  165
  Citations