What is she best known for?
The fields of study she is best known for:
Her primary scientific interests are in Biochemistry, Protein structure, Binding site, Phosphoinositide 3-kinase and Cell biology.
Her study in the fields of Second messenger system, Signal transduction, Phosphatidylinositol and Cyclin-dependent kinase 9 under the domain of Biochemistry overlaps with other disciplines such as Synaptotagmins.
Within one scientific family, Olga Perisic focuses on topics pertaining to SH3 domain under Binding site, and may sometimes address concerns connected to Plasma protein binding, PX domain and Stereochemistry.
Her Phosphoinositide 3-kinase research integrates issues from Protein subunit, Gene mutation and Kinase activity.
Her work deals with themes such as Heat shock protein, Nucleic acid sequence, Biophysics and Conserved sequence, which intersect with Protein subunit.
Her Cell biology study combines topics from a wide range of disciplines, such as ESCRT and ESCRT complex.
Her most cited work include:
- Structural Determinants of Phosphoinositide 3-kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine (923 citations)
- Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ (491 citations)
- Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta. (466 citations)
What are the main themes of her work throughout her whole career to date?
The scientist’s investigation covers issues in Cell biology, Biochemistry, Protein subunit, Kinase and Protein structure.
Her Cell biology research is multidisciplinary, incorporating elements of ESCRT and Endosome.
Her study in Biochemistry concentrates on Phosphorylation, Protein kinase A, Cyclin-dependent kinase 9, Lipid kinase activity and Kinase activity.
Her work focuses on many connections between Protein subunit and other disciplines, such as Plasma protein binding, that overlap with her field of interest in Allosteric regulation and SH3 domain.
Her Protein structure research incorporates elements of Genetics, Binding site, Phosphoinositide 3-kinase, Peptide sequence and SH2 domain.
Her studies in Peptide sequence integrate themes in fields like Stereochemistry and Cell membrane.
She most often published in these fields:
- Cell biology (44.59%)
- Biochemistry (39.19%)
- Protein subunit (27.03%)
What were the highlights of her more recent work (between 2010-2021)?
- Cell biology (44.59%)
- Protein subunit (27.03%)
- Biochemistry (39.19%)
In recent papers she was focusing on the following fields of study:
Olga Perisic mainly focuses on Cell biology, Protein subunit, Biochemistry, GTPase and Kinase.
Her study in Protein subunit is interdisciplinary in nature, drawing from both Protein structure, Cancer research, Ubiquitin ligase and Endocytosis.
Her research integrates issues of Biophysics, Membrane, Class Ia Phosphatidylinositol 3-Kinase and Binding site in her study of Protein structure.
Biochemistry is a component of her SH2 domain, Lipid kinase activity, Phosphorylation, PI4KB and Effector studies.
Olga Perisic interconnects Cell membrane and Active site in the investigation of issues within Phosphorylation.
Her research investigates the connection with GTPase and areas like Guanosine which intersect with concerns in GTP', Allosteric regulation, Small GTPase, Phosphatidylinositol and Cytokinesis.
Between 2010 and 2021, her most popular works were:
- Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage (370 citations)
- Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) (161 citations)
- Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism (129 citations)
In her most recent research, the most cited papers focused on:
Olga Perisic spends much of her time researching Cell biology, Protein subunit, Biochemistry, Protein structure and G protein-coupled receptor.
Her Cell biology study frequently draws parallels with other fields, such as Guanosine.
Her Protein subunit study integrates concerns from other disciplines, such as Transport protein, Ubiquitin, ESCRT and Immediate early protein.
Many of her studies on Biochemistry apply to Cytokinesis as well.
She has included themes like Class Ia Phosphatidylinositol 3-Kinase, PIK3CG, SH2 domain, Class Ib Phosphatidylinositol 3-Kinase and Conformational change in her Protein structure study.
The G protein-coupled receptor study combines topics in areas such as Heterotrimeric G protein, G protein, Receptor tyrosine kinase and PTEN.
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