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Georgios Skiniotis

Georgios Skiniotis

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
20055
World Ranking
7690
National Ranking
3505

Overview

Georgios Skiniotis is affiliated with Stanford University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a substantial contribution to molecular biology within this field. Other notable subfields of study include cellular and molecular neuroscience, materials chemistry, radiology, nuclear medicine and imaging, and spectroscopy.

Their scientific work addresses several main topics related to receptor mechanisms and signaling, neuropeptides and animal physiology, mass spectrometry techniques and applications, monoclonal and polyclonal antibodies research, pharmacological receptor mechanisms and effects, protein structure and dynamics, and chemical synthesis and alkaloids.

Skiniotis has co-authored numerous publications, frequently collaborating with the following researchers:

  • Michael J. Robertson
  • Ouliana Panova
  • Alpay B. Seven
  • Brian K. Kobilka
  • Ximena Barros-Álvarez

Their research has been published extensively in various scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • EMPIAR dataset
  • Nature Structural & Molecular Biology
  • Nature Communications

Some recent papers authored by Skiniotis cover significant findings in receptor structure and signaling mechanisms. These include:

  • Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor, 2020, Cell
  • Structure of the neurotensin receptor 1 in complex with β-arrestin 1, 2020, Nature
  • Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc, 2020, Nature
  • Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity, 2022, Nature
  • Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells, 2021, Cell

Best Publications

  • Crystal structure of the β2 adrenergic receptor-Gs protein complex.

    Søren G. F. Rasmussen;Brian T. DeVree;Yaozhong Zou;Andrew C. Kruse

  • Structure of the µ-opioid receptor–G i protein complex

    Antoine Koehl;Hongli Hu;Shoji Maeda;Yan Zhang

  • GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

    Alex R.B. Thomsen;Bianca Plouffe;Thomas J. Cahill;Arun K. Shukla

  • Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

    Yan Zhang;Bingfa Sun;Dan Feng;Hongli Hu

  • Visualization of arrestin recruitment by a G-protein-coupled receptor

    Arun K. Shukla;Gerwin H. Westfield;Kunhong Xiao;Rosana I. Reis

  • Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

    Yi Lynn Liang;Maryam Khoshouei;Mazdak Radjainia;Yan Zhang

  • Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

    Kuglae Kim;Tao Che;Ouliana Panova;Jeffrey F. DiBerto

  • Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.

    David L. Akey;W. Clay Brown;Somnath Dutta;Jamie Konwerski

  • Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

    Weijiao Huang;Matthieu Masureel;Qianhui Qu;John Janetzko

  • Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

    Kaavya Krishna Kumar;Moran Shalev-Benami;Michael J. Robertson;Hongli Hu

  • Structure of a modular polyketide synthase

    Somnath Dutta;Jonathan R. Whicher;Douglas A. Hansen;Wendi A. Hale

  • Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

    Thomas J. Cahill;Alex R.B. Thomsen;Jeffrey T. Tarrasch;Bianca Plouffe

  • Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes.

    Shoji Maeda;Qianhui Qu;Michael J. Robertson;Georgios Skiniotis

  • Structure of the M2 Muscarinic Receptor-β-Arrestin Complex in a Lipid Nanodisc

    Dean P. Staus;Dean P. Staus;Hongli Hu;Hongli Hu;Michael J. Robertson;Alissa L. W. Kleinhenz;Alissa L. W. Kleinhenz;Alissa L. W. Kleinhenz

  • Structural insights into the activation of metabotropic glutamate receptors.

    Antoine Koehl;Hongli Hu;Dan Feng;Bingfa Sun

  • Structural flexibility of the Gαs α-helical domain in the β 2-adrenoceptor Gs complex

    Gerwin H. Westfield;Søren G. F. Rasmussen;Søren G. F. Rasmussen;Min Su;Somnath Dutta

  • Structure of the mu-opioid receptor-Giprotein complex.

    Antoine Koehl;Hongli Hu;Shoji Maeda;Yan Zhang

  • Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates.

    Bethany S. Strunk;Bethany S. Strunk;Cherisse R. Loucks;Min Su;Harish Vashisth

  • Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

    Eric J. Drake;Bradley R. Miller;Ce Shi;Jeffrey T. Tarrasch

  • Inhibition of AMPK catabolic action by GSK3

    Tsukasa Suzuki;Dave Bridges;Daisuke Nakada;Georgios Skiniotis

Frequent Co-Authors

Brian K. Kobilka
Brian K. Kobilka Stanford University
William I. Weis
William I. Weis Stanford University
Thomas Walz
Thomas Walz Rockefeller University
Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Jan Steyaert
Jan Steyaert Vrije Universiteit Brussel
Janet L. Smith
Janet L. Smith University of Michigan–Ann Arbor
Ali Shilatifard
Ali Shilatifard Northwestern University
Asuka Inoue
Asuka Inoue Tohoku University
Roger K. Sunahara
Roger K. Sunahara University of California, San Diego
David H. Sherman
David H. Sherman University of Michigan–Ann Arbor

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