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Hisanori Horiuchi

Hisanori Horiuchi

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9078
World Ranking
16739
National Ranking
1198

Overview

Hisanori Horiuchi is affiliated with Tohoku University in Japan and has contributed extensively to the field of medicine. Their research spans multiple subfields including surgery, cardiology and cardiovascular medicine, hematology, biomedical engineering, and molecular biology.

The scientist's main research topics include:

  • Mechanical Circulatory Support Devices
  • Platelet Disorders and Treatments
  • COVID-19 Clinical Research Studies
  • Cardiac Valve Diseases and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Abdominal vascular conditions and treatments
  • Atrial Fibrillation Management and Outcomes

Several recent papers demonstrate the breadth of Horiuchi's work:

  • "A SNARE geranylgeranyltransferase essential for the organization of the Golgi apparatus," 2020, The EMBO Journal
  • "COVID-19-Related Thrombosis in Japan: Final Report of a Questionnaire-Based Survey in 2020," 2021, Journal of Atherosclerosis and Thrombosis
  • "Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma," 2021, Cancer Science
  • "Double prenylation of SNARE protein Ykt6 is required for lysosomal hydrolase trafficking," 2020, The Journal of Biochemistry
  • "Gastrointestinal Angiodysplasia before and after Treatment of Severe Aortic Stenosis," 2023, New England Journal of Medicine

Horiuchi frequently collaborates with other researchers, the most frequent co-authors being:

  • Ryutaro Shirakawa
  • Kota Goto
  • Eriko Morishita
  • Noriyuki Okubo
  • Masanori Matsumoto

The scientist commonly publishes in the following venues:

  • Research and Practice in Thrombosis and Haemostasis
  • Journal of Atherosclerosis and Thrombosis
  • Journal of Biological Chemistry
  • PubMed
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function

    Hisanori Horiuchi;Roger Lippé;Heidi M. McBride;Mariantonietta Rubino

  • Restenosis after percutaneous transluminal coronary angioplasty: pathologic observations in 20 patients.

    Masakiyo Nobuyoshi;Takeshi Kimura;Hiroto Ohishi;Hisanori Horiuchi

  • Nationwide survey of hemophagocytic lymphohistiocytosis in Japan.

    Eiichi Ishii;Shouichi Ohga;Shinsaku Imashuku;Masaki Yasukawa

  • Cutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells.

    Harunobu Ozaki;Kenji Ishii;Hisanori Horiuchi;Hidenori Arai

  • Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange.

    Oliver Ullrich;Hisanori Horiuchi;Cecilia Bucci;Marino Zerial

  • Role of oxidized LDL in atherosclerosis.

    Toru Kita;Noriaki Kume;Manabu Minami;Kazutaka Hayashida

  • RAB ESCORT PROTEIN-1 IS A MULTIFUNCTIONAL PROTEIN THAT ACCOMPANIES NEWLY PRENYLATED RAB PROTEINS TO THEIR TARGET MEMBRANES

    Kirill Alexandrov;Hisanori Horiuchi;Olivia Steele-Mortimer;Miguel C. Seabra

  • Munc13-4 Is a GTP-Rab27-binding Protein Regulating Dense Core Granule Secretion in Platelets

    Ryutaro Shirakawa;Tomohito Higashi;Arata Tabuchi;Akira Yoshioka

  • Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions

    Eiichi Ishii;Ikuyo Ueda;Ryutaro Shirakawa;Ken Yamamoto

  • Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis.

    Koji Nagafuji;Atsushi Nonami;Takashi Kumano;Yoshikane Kikushige

  • A possible target protein for smg-25A/rab3A small GTP-binding protein.

    H Shirataki;K Kaibuchi;T Yamaguchi;K Wada

  • Involvement of nectin in the localization of junctional adhesion molecule at tight junctions.

    Atsunori Fukuhara;Kenji Irie;Hiroyuki Nakanishi;Kyoji Takekuni

  • Small GTPase Rab4 Regulates Ca2+-induced α-Granule Secretion in Platelets

    Ryutaro Shirakawa;Akira Yoshioka;Hisanori Horiuchi;Hiroaki Nishioka

  • Impact of CYP2C19 polymorphisms on the antiplatelet effect of clopidogrel in an actual clinical setting in Japan

    Toshikazu Jinnai;Hisanori Horiuchi;Takeru Makiyama;Junichi Tazaki

  • Serum adiponectin level as an independent predictor of mortality in patients with congestive heart failure.

    Toshihiro Tamura;Yutaka Furukawa;Ryoji Taniguchi;Yukihito Sato

  • Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity

    Takahiro Horiuchi;Natsumi Sakata;Yoshihiro Narumi;Tomohiro Kimura

  • Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion

    Kristin L. Boswell;Declan J. James;Joseph M. Esquibel;Stephen Bruinsma

  • Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

    Stephanie M. Wood;Stephanie M. Wood;Marie Meeths;Samuel C.C. Chiang;Anne Grete Bechensteen

  • The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21.

    M. Katayama;M. Kawata;Y. Yoshida;H. Horiuchi

  • Seven-transmembrane receptors

    Hisanori Horiuchi

Frequent Co-Authors

Toru Kita
Toru Kita Kyoto University
Takeshi Kimura
Takeshi Kimura Kyoto University
Osamu Nureki
Osamu Nureki University of Tokyo
Marino Zerial
Marino Zerial Max Planck Society
Hidenori Arai
Hidenori Arai Kyoto University
Yoshimi Takai
Yoshimi Takai Kobe University
Katsuya Okawa
Katsuya Okawa Kyowa Kirin (Japan)
Noriaki Kume
Noriaki Kume Kobe Gakuin University
Masaki Yasukawa
Masaki Yasukawa Ehime University
Shouichi Ohga
Shouichi Ohga Kyushu University

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