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Biology and Biochemistry

D-Index
61
Citations
15417
World Ranking
11234
National Ranking
773

Overview

Noriaki Kume is a researcher affiliated with Kobe Gakuin University in Japan. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Molecular Biology, Epidemiology, Cognitive Neuroscience, Experimental and Cognitive Psychology, and Physical Therapy, Sports Therapy and Rehabilitation.

The scientist's research interests encompass a range of topics related to health and biological processes. Notably, these include:

  • Sleep and related disorders
  • Balance, Gait, and Falls Prevention
  • Sleep and Wakefulness Research
  • Liver Disease Diagnosis and Treatment
  • Adipose Tissue and Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Cholesterol and Lipid Metabolism

Kume has contributed to several recent publications, primarily in the journal Biological and Pharmaceutical Bulletin. Representative papers include:

  • Association of Hypnotic Drug Use with Fall Incidents in Hospitalized Elderly Patients: A Case-Crossover Study (2020, Biological and Pharmaceutical Bulletin)
  • Reduced Serum Cholesterol and Triglyceride Levels in a Choline-Deficient L-Amino Acid-Defined High-Fat Diet (CDAHFD)-Induced Mouse Model of Non-alcoholic Steatohepatitis (NASH) (2020, Biological and Pharmaceutical Bulletin)
  • Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels (2021, Biological and Pharmaceutical Bulletin)

Their research output often involves collaboration with several co-authors, indicating a range of collaborative projects. Frequent co-authors include Haruki Torii, Rumiko Shimizu, Daisuke Yasuda, Yoshinori Hiraoka, and Motozumi Ando.

Kume's work on sleep disorders and fall prevention overlaps with topics in epidemiology and physical therapy, reflecting an interdisciplinary approach to health research. In addition, their studies on liver disease and lipid metabolism involve molecular biology techniques and biochemical analysis, linking clinical conditions with underlying biochemical mechanisms.

The research contributions signal a sustained engagement with issues related to aging, metabolism, and neurological function, as evidenced by the publications addressing hypnotic drug use and fall incidents, as well as metabolic conditions such as non-alcoholic steatohepatitis.

Best Publications

  • An endothelial receptor for oxidized low-density lipoprotein

    Tatsuya Sawamura;Noriaki Kume;Takuma Aoyama;Hideaki Moriwaki

  • Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia

    Toru Kita;Yutaka Nagano;Masayuki Yokode;Kenji Ishii

  • Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

    N Kume;M I Cybulsky;M A Gimbrone

  • Expression of Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 in Human Atherosclerotic Lesions

    Hiroharu Kataoka;Noriaki Kume;Susumu Miyamoto;Manabu Minami

  • Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells

    Kozo Oka;Tatsuya Sawamura;Ken-ichiro Kikuta;Shigekazu Itokawa

  • Inducible Expression of Lectin-like Oxidized LDL Receptor-1 in Vascular Endothelial Cells

    Noriaki Kume;Takatoshi Murase;Hideaki Moriwaki;Takuma Aoyama

  • Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells.

    Noriaki Kume;Michael A. Gimbrone Jr.

  • Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages.

    Takeshi Shimaoka;Noriaki Kume;Manabu Minami;Kazutaka Hayashida

  • Role of oxidized LDL in atherosclerosis.

    Toru Kita;Noriaki Kume;Manabu Minami;Kazutaka Hayashida

  • Serum Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Elevated in Acute Coronary Syndrome A Novel Marker for Early Diagnosis

    Kazutaka Hayashida;Noriaki Kume;Takatoshi Murase;Manabu Minami

  • Fluid Shear Stress Transcriptionally Induces Lectin-like Oxidized LDL Receptor-1 in Vascular Endothelial Cells

    Takatoshi Murase;Noriaki Kume;Risa Korenaga;Joji Ando

  • Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells.

    Takeshi Shimaoka;Takashi Nakayama;Noriko Fukumoto;Noriaki Kume

  • Oxidized LDL Modulates Bax/Bcl-2 Through the Lectinlike Ox-LDL Receptor-1 in Vascular Smooth Muscle Cells

    Hiroharu Kataoka;Noriaki Kume;Susumu Miyamoto;Manabu Minami

  • MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE−/− Mice

    Takahiro Horie;Osamu Baba;Yasuhide Kuwabara;Yoshimasa Chujo

  • Ligand Specificity of LOX-1, a Novel Endothelial Receptor for Oxidized Low Density Lipoprotein

    Hideaki Moriwaki;Noriaki Kume;Tatsuya Sawamura;Takuma Aoyama

  • Expression of SR-PSOX, a Novel Cell-Surface Scavenger Receptor for Phosphatidylserine and Oxidized LDL in Human Atherosclerotic Lesions

    Manabu Minami;Noriaki Kume;Takeshi Shimaoka;Hiroharu Kataoka

  • Identification of Soluble Forms of Lectin-Like Oxidized LDL Receptor-1

    Takatoshi Murase;Noriaki Kume;Hiroharu Kataoka;Manabu Minami

  • LOX-1 supports adhesion of Gram-positive and Gram-negative bacteria.

    Takeshi Shimaoka;Noriaki Kume;Manabu Minami;Kazutaka Hayashida

  • Increased Expression of Lectinlike Oxidized Low Density Lipoprotein Receptor-1 in Initial Atherosclerotic Lesions of Watanabe Heritable Hyperlipidemic Rabbits

    Mingyi Chen;Makoto Kakutani;Manabu Minami;Hiroharu Kataoka

  • MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

    Takahiro Horie;Tomohiro Nishino;Osamu Baba;Yasuhide Kuwabara

Frequent Co-Authors

Toru Kita
Toru Kita Kyoto University
Chuichi Kawai
Chuichi Kawai Kyoto University
Shin Yonehara
Shin Yonehara Kyoto University
Tatsuya Sawamura
Tatsuya Sawamura Shinshu University
Hidenori Arai
Hidenori Arai Kyoto University
Tomoh Masaki
Tomoh Masaki Kyoto University
Nobuo Hashimoto
Nobuo Hashimoto Kyoto University
Susumu Miyamoto
Susumu Miyamoto Kyoto University
Takeshi Kimura
Takeshi Kimura Kyoto University
Kenji Ishii
Kenji Ishii Nippon Medical School

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