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Frédéric H.-T. Allain

Frédéric H.-T. Allain

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
20208
World Ranking
4146
National Ranking
82

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Frédéric H.-T. Allain is affiliated with ETH Zurich in Switzerland and focuses primarily on research within the field of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Spectroscopy, Materials Chemistry, Genetics, and Neurology.

The scientist's research concentrates on topics such as RNA Research and Splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, Advanced NMR Techniques and Applications, Protein Structure and Dynamics, Neurogenetic and Muscular Disorders Research, and RNA regulation and disease.

Frequent publication venues for Allain include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Zenodo (CERN European Organization for Nuclear Research)
  • Angewandte Chemie International Edition

Among the recent papers published by this scientist are:

  • The diversity of splicing modifiers acting on A -1 bulged 5 -splice sites reveals rules for rational drug design, 2024, HAL (Le Centre pour la Communication Scientifique Directe)
  • Structural basis for Cas9 off-target activity, 2022, Cell
  • RNA-PROTACs: Degraders of RNA-Binding Proteins, 2020, Angewandte Chemie International Edition
  • NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation, 2021, Nature Chemical Biology
  • Non-specific adhesive forces between filaments and membraneless organelles, 2022, Nature Physics

Frequent coauthors collaborating with Allain include Leonidas Emmanouilidis, Antoine Cléry, Gunnar Jeschke, Fred F. Damberger, and Maxim Yulikov.

Best Publications

  • The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression

    Christophe Maris;Cyril Dominguez;Frédéric H.-T. Allain

  • RNA recognition motifs: boring? Not quite.

    Antoine Cléry;Markus Blatter;Frédéric H.-T. Allain

  • Gac/Rsm signal transduction pathway of γ‐proteobacteria: from RNA recognition to regulation of social behaviour

    Karine Lapouge;Mario Schubert;Frédéric H.‐T. Allain;Dieter Haas

  • SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

    Eunhee Kim;Janine O. Ilagan;Yang Liang;Gerrit M. Daubner

  • Structure of PTB bound to RNA: specific binding and implications for splicing regulation.

    Florian C. Oberstrass;Sigrid D. Auweter;Michèle Erat;Yann Hargous

  • NMR investigation of RNA structure

    Gabriele Varani;Fareed Aboul-ela;Frédéric H.-T. Allain

  • Structure of the P1 helix from group I self-splicing introns.

    Frédéric H.-T. Allain;Gabriele Varani

  • Sequence-specific binding of single-stranded RNA: is there a code for recognition?

    Sigrid D. Auweter;Florian C. Oberstrass;Frédéric H.-T. Allain

  • Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

    Peter J Lukavsky;Dalia Daujotyte;Dalia Daujotyte;James R Tollervey;James R Tollervey;Jernej Ule;Jernej Ule

  • Specificity of ribonucleoprotein interaction determined by RNA folding during complex formation

    Frédéric H.-T. Allain;Charles C. Gubser;Peter W. A. Howe;Kiyoshi Nagai

  • SRSF1-Regulated Alternative Splicing in Breast Cancer.

    Olga Anczuków;Martin Akerman;Antoine Cléry;Jie Wu

  • Molecular basis of RNA recognition by the human alternative splicing factor Fox-1

    Sigrid D. Auweter;Rudi Fasan;Luc Reymond;Jason G. Underwood

  • RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence.

    Grégoire Masliah;Pierre Barraud;Frédéric H. T. Allain

  • The YTH domain is a novel RNA binding domain.

    Zhaiyi Zhang;Dominik Theler;Katarzyna H. Kaminska;Katarzyna H. Kaminska;Michael Hiller

  • Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.

    Frédéric H.-T. Allain;Philippe Bouvet;Thorsten Dieckmann;Thorsten Dieckmann;Juli Feigon

  • The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.

    Richard Stefl;Florian C. Oberstrass;Jennifer L. Hood;Muriel Jourdan

  • Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.

    Tariq Afroz;Eva-Maria Hock;Patrick Ernst;Chiara Foglieni

  • RRM-RNA recognition: NMR or crystallography…and new findings.

    Gerrit M. Daubner;Antoine Cléry;Frédéric H.-T. Allain

  • RNA sequence- and shape-dependent recognition by proteins in the ribonucleoprotein particle

    Richard Stefl;Lenka Skrisovska;Frédéric H.‐T. Allain

  • Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA

    Mario Schubert;Karine Lapouge;Olivier Duss;Florian C. Oberstrass

Frequent Co-Authors

Juli Feigon
Juli Feigon University of California, Los Angeles
Gabriele Varani
Gabriele Varani University of Washington
Gunnar Jeschke
Gunnar Jeschke ETH Zurich
Markus Aebi
Markus Aebi ETH Zurich
Jiří Šponer
Jiří Šponer Masaryk University
Beat Ernst
Beat Ernst University of Basel
Adrian R. Krainer
Adrian R. Krainer Cold Spring Harbor Laboratory
Stefan Stamm
Stefan Stamm University of Kentucky
Mihaela Zavolan
Mihaela Zavolan University of Basel

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