D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 13,470 194 World Ranking 8796 National Ranking 639

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Internal medicine

His main research concerns Biochemistry, Internal medicine, Endocrinology, Monoclonal antibody and Lipoprotein. His study ties his expertise on Molecular biology together with the subject of Biochemistry. His studies examine the connections between Internal medicine and genetics, as well as such issues in Heme oxygenase, with regards to Lesion.

Hiroyuki Itabe combines subjects such as Immunoassay, Unstable angina, Angina and Cardiology with his study of Endocrinology. In his study, Peptide, Immunohistochemistry and Foam cell is strongly linked to Antigen, which falls under the umbrella field of Monoclonal antibody. His work deals with themes such as Low-density lipoprotein and Apolipoprotein B, which intersect with Antibody.

His most cited work include:

  • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. (734 citations)
  • Single LDL Apheresis Improves Endothelium-Dependent Vasodilatation in Hypercholesterolemic Humans (505 citations)
  • Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. (493 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Biochemistry, Lipoprotein, Endocrinology and Cell biology. In his research on the topic of Internal medicine, Restenosis is strongly related with Cardiology. His biological study deals with issues like Molecular biology, which deal with fields such as Scavenger receptor and Apoptosis.

His work carried out in the field of Lipoprotein brings together such families of science as Oxidative phosphorylation, Monoclonal antibody and Pathology. His biological study spans a wide range of topics, including Immunohistochemistry and Antigen. His Endocrinology research is multidisciplinary, incorporating elements of Immunology and Hemodialysis.

He most often published in these fields:

  • Internal medicine (39.70%)
  • Biochemistry (29.15%)
  • Lipoprotein (26.63%)

What were the highlights of his more recent work (between 2013-2021)?

  • Internal medicine (39.70%)
  • Cell biology (17.09%)
  • Lipoprotein (26.63%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Internal medicine, Cell biology, Lipoprotein, Biochemistry and Endocrinology. His Internal medicine study integrates concerns from other disciplines, such as Laser capture microdissection and Nephropathy. Hiroyuki Itabe interconnects Endothelium, Macrophage, Calpain and Exon in the investigation of issues within Cell biology.

His research on Lipoprotein also deals with topics like

  • Myeloperoxidase and related Incubation and Molecular biology,
  • Western blot most often made with reference to Neutrophil extracellular traps. His Endocrinology study incorporates themes from Periodontitis and Pathogenesis. His Myocardial infarction research incorporates elements of Monoclonal antibody, Tunica media and Coronary atherosclerosis.

Between 2013 and 2021, his most popular works were:

  • Perilipins: a diversity of intracellular lipid droplet proteins (85 citations)
  • Characterization of lipid droplets in steroidogenic MLTC-1 Leydig cells: Protein profiles and the morphological change induced by hormone stimulation. (22 citations)
  • Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing (17 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Internal medicine

Hiroyuki Itabe mainly investigates Biochemistry, Cell biology, Lipid droplet, Lipoprotein and Cholesterol. His work in Biochemistry is not limited to one particular discipline; it also encompasses Stimulation. The study incorporates disciplines such as Calpain, Atheroma and Exon in addition to Cell biology.

His Lipid droplet research incorporates themes from Lipid metabolism, Endocrinology, Mesenchymal stem cell and Perilipin. The various areas that Hiroyuki Itabe examines in his Lipoprotein study include Low-density lipoprotein, Lysophosphatidylcholine, Phosphatidylcholine, Lipid peroxidation and Oxidative phosphorylation. His study looks at the relationship between Cholesterol and topics such as C-reactive protein, which overlap with Pharmacology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes.

Shoichi Ehara;Makiko Ueda;Takahiko Naruko;Kazuo Haze.
Circulation (2001)

1178 Citations

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.

Sohvi Hörkkö;David A. Bird;Elizabeth Miller;Hiroyuki Itabe.
Journal of Clinical Investigation (1999)

786 Citations

Single LDL Apheresis Improves Endothelium-Dependent Vasodilatation in Hypercholesterolemic Humans

Osamu Tamai;Hidehiro Matsuoka;Hiroyuki Itabe;Yoshifumi Wada.
Circulation (1997)

778 Citations

Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease

Shun-ichi Toshima;Akira Hasegawa;Masahiko Kurabayashi;Hiroyuki Itabe.
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)

550 Citations

Oxidized LDL in Carotid Plaques and Plasma Associates With Plaque Instability

Kyoko Nishi;Hiroyuki Itabe;Masaaki Uno;Keiko T. Kitazato.
Arteriosclerosis, Thrombosis, and Vascular Biology (2002)

508 Citations

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

Yasuyuki Fujimoto;Hiroyuki Itabe;Jun Sakai;Minoru Makita.
Biochimica et Biophysica Acta (2004)

430 Citations

A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides.

H Itabe;E Takeshima;H Iwasaki;J Kimura.
Journal of Biological Chemistry (1994)

407 Citations

Sensitive detection of oxidatively modified low density lipoprotein using a monoclonal antibody.

H Itabe;H Yamamoto;T Imanaka;K Shimamura.
Journal of Lipid Research (1996)

387 Citations

Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice

Kazunobu Ishikawa;Daisuke Sugawara;Xu-ping Wang;Kazunori Suzuki.
Circulation Research (2001)

358 Citations

Hemodialysis Impairs Endothelial Function via Oxidative Stress : Effects of Vitamin E-Coated Dialyzer

Hiroshi Miyazaki;Hidehiro Matsuoka;Hiroyuki Itabe;Michiaki Usui.
Circulation (2000)

320 Citations

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