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Shin-ichiro Imai

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
31907
World Ranking
13506
National Ranking
5728

Shin-ichiro Imai publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Shin-ichiro Imai sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 138 publications — 21st percentile

21% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Shin-ichiro Imai D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Shin-ichiro Imai sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Shin-ichiro Imai is affiliated with Washington University in St. Louis in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on physiology, geriatrics and gerontology, molecular biology, surgery, and endocrine and autonomic systems.

The scientist's work covers key topics such as adipose tissue and metabolism, sirtuins and resveratrol in medicine, calcium signaling and nucleotide metabolism, mitochondrial function and pathology, genetics, aging, and longevity in model organisms, circadian rhythm and melatonin, and dietary effects on health.

Some recent notable papers authored by Shin-ichiro Imai include:

  • Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women, 2021, Science
  • SS-31 and NMN: Two paths to improve metabolism and function in aged hearts, 2020, Aging Cell
  • Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging, 2022, Cell Reports
  • Friends and foes: Extracellular vesicles in aging and rejuvenation, 2021, FASEB BioAdvances
  • DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication, 2024, Cell Metabolism

Their publication record also indicates frequent contributions to several venues, including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • npj Aging
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Science

Shin-ichiro Imai's collaborative network includes frequent coauthors such as Kyohei Tokizane, Cynthia S. Brace, Kathryn F. Mills, Kiyoshi Yoshioka, and Norihiko Furusawa.

Best Publications

  • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

    Shin-ichiro Imai;Christopher M. Armstrong;Matt Kaeberlein;Leonard Guarente

  • hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

    Homayoun Vaziri;Scott K. Dessain;Scott K. Dessain;Elinor Ng Eaton;Shin Ichiro Imai

  • Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

    Jianyuan Luo;Anatoly Y. Nikolaev;Shin ichiro Imai;Delin Chen

  • Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

    Jun Yoshino;Kathryn F. Mills;Myeong Jin Yoon;Shin-ichiro Imai

  • NAD+ and sirtuins in aging and disease

    Shin-Ichiro Imai;Leonard Pershing Guarente

  • Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

    Kathryn Moynihan Ramsey;Jun Yoshino;Cynthia S. Brace;Dana Abrassart

  • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.

    Javier R. Revollo;Andrew A. Grimm;Shin Ichiro Imai

  • Nampt/PBEF/visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme

    Javier R. Revollo;Antje Körner;Kathryn F. Mills;Akiko Satoh

  • Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice

    Kathryn A. Moynihan;Andrew A. Grimm;Marie M. Plueger;Ernesto Bernal-Mizrachi

  • NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

    Jun Yoshino;Joseph A. Baur;Shin ichiro Imai;Shin ichiro Imai

  • Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH

    Akiko Satoh;Cynthia S. Brace;Nick Rensing;Paul Cliften

  • Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.

    Kathryn F. Mills;Shohei Yoshida;Liana R. Stein;Alessia Grozio

  • The dynamic regulation of NAD metabolism in mitochondria

    Liana Roberts Stein;Shin-ichiro Imai

  • Nampt: linking NAD biology, metabolism and cancer.

    Antje Garten;Stefanie Petzold;Antje Körner;Shin-ichiro Imai

  • Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2α Deacetylase Activity *

    Jyothish B. Pillai;Ayman Isbatan;Shin Ichiro Imai;Mahesh P. Gupta

  • Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

    Shin-ichiro Imai;Leonard Pershing Guarente

  • Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance

    Jun Yoshino;Caterina Conte;Caterina Conte;Luigi Fontana;Bettina Mittendorfer

  • The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals.

    Javier R Revollo;Andrew A Grimm;Shin-ichiro Imai

  • Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice.

    Kathryn Moynihan Ramsey;Kathryn F. Mills;Akiko Satoh;Shin Ichiro Imai

  • Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

    Tao Wang;Xiangbin Zhang;Poonam Bheda;Javier R. Revollo

Frequent Co-Authors

Leonard Guarente
Leonard Guarente MIT
Kazuo Tsubota
Kazuo Tsubota Keio University
Wieland Kiess
Wieland Kiess Leipzig University
Cynthia Wolberger
Cynthia Wolberger Johns Hopkins University School of Medicine
Joseph A. Baur
Joseph A. Baur University of Pennsylvania
Santina Bruzzone
Santina Bruzzone University of Genoa
Yo-ichi Nabeshima
Yo-ichi Nabeshima Foundation for Biomedical Research
Junichi Sadoshima
Junichi Sadoshima Rutgers, The State University of New Jersey
Bruce W. Patterson
Bruce W. Patterson Washington University in St. Louis
Samuel Klein
Samuel Klein Washington University in St. Louis

External Links

Personal website of Shin-ichiro Imai

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Best Scientists Citing Shin-ichiro Imai

David A. Sinclair

David A. Sinclair

Harvard University

Publications: 139

Leonard Guarente

Leonard Guarente

MIT

Publications: 95

Johan Auwerx

Johan Auwerx

École Polytechnique Fédérale de Lausanne

Publications: 69

Eric Verdin

Eric Verdin

Buck Institute for Research on Aging

Publications: 67

Paolo Sassone-Corsi

Paolo Sassone-Corsi

University of California, Irvine

Publications: 64

Hening Lin

Hening Lin

Howard Hughes Medical Institute

Publications: 58

John M. Denu

John M. Denu

University of Wisconsin–Madison

Publications: 48

Wei Gu

Wei Gu

Columbia University

Publications: 42

Carles Cantó

Carles Cantó

Nestlé (Switzerland)

Publications: 41

Joseph A. Baur

Joseph A. Baur

University of Pennsylvania

Publications: 41

Charles Brenner

Charles Brenner

City Of Hope National Medical Center

Publications: 40

Anthony A. Sauve

Anthony A. Sauve

Cornell University

Publications: 40

Raul Mostoslavsky

Raul Mostoslavsky

Harvard University

Publications: 38

Rafael de Cabo

Rafael de Cabo

National Institutes of Health

Publications: 35

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Michael W. McBurney

University of Ottawa

Publications: 35

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Eduardo N. Chini

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