As part of his studies on Radiology, Shin-ichiro Imai frequently links adjacent subjects like Chemoradiotherapy. His Chemoradiotherapy study typically links adjacent topics like Radiology. His research on Internal medicine frequently links to adjacent areas such as Abdominal surgery. His Abdominal surgery study frequently involves adjacent topics like Internal medicine. The study of Membrane is intertwined with the study of Sphingomyelin phosphodiesterase in a number of ways. His research on Sphingomyelin phosphodiesterase often connects related topics like Membrane. His work often combines Apoptosis and Ceramide studies. Shin-ichiro Imai integrates Ceramide with Apoptosis in his study. He combines Biochemistry and Receptor in his studies.
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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Shin-ichiro Imai;Christopher M. Armstrong;Matt Kaeberlein;Leonard Guarente.
Nature (2000)
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
Homayoun Vaziri;Scott K. Dessain;Scott K. Dessain;Elinor Ng Eaton;Shin Ichiro Imai.
Cell (2001)
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
Jianyuan Luo;Anatoly Y. Nikolaev;Shin ichiro Imai;Delin Chen.
Cell (2001)
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis
Kathryn Moynihan Ramsey;Jun Yoshino;Cynthia S. Brace;Dana Abrassart.
Science (2009)
Nampt/PBEF/visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme
Javier R. Revollo;Antje Körner;Kathryn F. Mills;Akiko Satoh.
Cell Metabolism (2007)
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.
Javier R. Revollo;Andrew A. Grimm;Shin Ichiro Imai.
Journal of Biological Chemistry (2004)
Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
Jun Yoshino;Kathryn F. Mills;Myeong Jin Yoon;Shin-ichiro Imai.
Cell Metabolism (2011)
NAD+ and sirtuins in aging and disease
Shin-Ichiro Imai;Leonard Pershing Guarente.
Trends in Cell Biology (2014)
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
Kathryn A. Moynihan;Andrew A. Grimm;Marie M. Plueger;Ernesto Bernal-Mizrachi.
Cell Metabolism (2005)
Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH
Akiko Satoh;Cynthia S. Brace;Nick Rensing;Paul Cliften.
Cell Metabolism (2013)
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