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Neuroscience

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Overview

Jeffrey H. Kordower is affiliated with Arizona State University in the United States. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with a strong focus on Neurology, Cellular and Molecular Neuroscience, Molecular Biology, Physiology, and Genetics.

The scientist's main research topics include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nerve injury and regeneration
  • Alzheimer's disease research and treatments
  • Genetic Neurodegenerative Diseases
  • Autism Spectrum Disorder Research

Jeffrey H. Kordower has collaborated frequently with the following co-authors:

  • Yaping Chu
  • Ashley S. Harms
  • Fredric P. Manfredsson
  • Tyler Tittle
  • Bryan A. Killinger

They have published multiple papers in notable venues, with frequent appearances in:

  • Movement Disorders
  • Acta Neuropathologica Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Brain

Recent notable papers include:

  • Disease modification and biomarker development in Parkinson disease, 2020, Neurology
  • Nigrostriatal tau pathology in parkinsonism and Parkinson's disease, 2023, Brain
  • T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease, 2020, Acta Neuropathologica
  • Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9, 2021, Gene Therapy
  • Inflammation in Experimental Models of α-Synucleinopathies, 2020, Movement Disorders

Best Publications

  • Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

    Sonja Kriks;Jae Won Shim;Jinghua Piao;Yosif M. Ganat

  • Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

    Jeffrey H Kordower;Yaping Chu;Robert A Hauser;Thomas B Freeman

  • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease†

    C. Warren Olanow;Christopher G. Goetz;Jeffrey H. Kordower;A. Jon Stoessl

  • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

    Jeffrey H. Kordower;Marina E. Emborg;Jocelyne Bloch;Shuang Y. Ma

  • Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

    Jeffrey H. Kordower;C. Warren Olanow;Hemraj B. Dodiya;Yaping Chu

  • A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

    Mark H Tuszynski;Mark H Tuszynski;Leon Thal;Leon Thal;Mary Pay;David P Salmon

  • Neuropathological Evidence of Graft Survival and Striatal Reinnervation after the Transplantation of Fetal Mesencephalic Tissue in a Patient with Parkinson's Disease

    J H Kordower;T B Freeman;B J Snow;F J Vingerhoets

  • Missing pieces in the Parkinson's disease puzzle.

    Jose A Obeso;Maria C Rodriguez-Oroz;Christopher G Goetz;Concepcion Marin;Concepcion Marin

  • Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

    Christopher B. Forsyth;Kathleen M. Shannon;Jeffrey H. Kordower;Robin M. Voigt

  • Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

    J.A. Obeso;M. Stamelou;M. Stamelou;C.G. Goetz;W. Poewe

  • Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

    Steven T. Dekosky;Milos D. Ikonomovic;Scot D. Styren;Laurel A Beckett

  • Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial.

    William J Marks;Raymond T Bartus;Joao Siffert;Charles S Davis

  • Fetal Nigral Transplantation as a Therapy for Parkinson's Disease

    C.W. Olanow;J.H. Kordower;T.B. Freeman

  • Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.

    Jeffrey H. Kordower;Yaping Chu;Glenn T. Stebbins;Steven T. DeKosky

  • Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

    Timothy J. Collier;Nicholas M. Kanaan;Jeffrey H. Kordower

  • Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

    Anamitra Ghosh;Avik Roy;Xiaojuan Liu;Jeffrey H. Kordower

  • Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease

    Kathleen M. Shannon;Ali Keshavarzian;Ece Mutlu;Hemraj B. Dodiya

  • Is alpha-synuclein in the colon a biomarker for premotor Parkinson's Disease? Evidence from 3 cases†‡§

    Kathleen M. Shannon;Ali Keshavarzian;Hemraj B. Dodiya;Shriram Jakate

  • Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease

    Thomas B. Freeman;C. Warren Olanow;Robert A. Hauser;G. Michael Nauert

  • Age-associated increases of α-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

    Yaping Chu;Jeffrey H. Kordower

  • Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease.

    Jeffrey H. Kordower;Stephane Palfi;Er-Yun Chen;Shuang Y. Ma

  • Transplantation of embryonic dopamine neurons for severe Parkinson's disease.

    C W Olanow;T Freeman;J Kordower

Frequent Co-Authors

Elliott J. Mufson
Elliott J. Mufson Barrow Neurological Institute
Yaping Chu
Yaping Chu Rush University Medical Center
C. Warren Olanow
C. Warren Olanow Icahn School of Medicine at Mount Sinai
Raymond T. Bartus
Raymond T. Bartus RTBioconsultants
Thomas B. Freeman
Thomas B. Freeman University of South Florida
Roy A.E. Bakay
Roy A.E. Bakay Rush University Medical Center
Christopher G. Goetz
Christopher G. Goetz Rush University Medical Center
Dwaine F. Emerich
Dwaine F. Emerich Alkermes (Ireland)
Patrick Aebischer
Patrick Aebischer École Polytechnique Fédérale de Lausanne
Patrik Brundin
Patrik Brundin Roche (United States)

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