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Raymond T. Bartus

Raymond T. Bartus

D-Index & Metrics

Medicine

D-Index
85
Citations
31203
World Ranking
14480
National Ranking
38

Overview

Raymond T. Bartus is affiliated with RTBioconsultants in Ireland and focuses primarily on research within Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work bridges multiple subfields including Molecular Biology, Genetics, Neurology, Cellular and Molecular Neuroscience, and Biomaterials.

The scientist has been involved in investigations relating to Amyotrophic Lateral Sclerosis Research and Neurogenetic and Muscular Disorders Research. Their research interests also encompass RNA Interference and Gene Delivery, Nerve Injury and Regeneration, Signaling Pathways in Disease, biodegradable polymer synthesis and properties, and CRISPR and Genetic Engineering.

Raymond T. Bartus has published several papers across a range of reputable scientific venues. Some of their recent publications include:

  • "Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease" (2020, Brain)
  • "Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis" (2023, PLoS ONE)
  • "Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy" (2020, UNC Libraries)
  • "Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: a potential new treatment route for amyotrophic lateral sclerosis" (2022, bioRxiv (Cold Spring Harbor Laboratory))

Their frequent collaborators include Orion P. Keifer, Mark T. Butt, Sarah D. Cramer, Malú G. Tansey, and Daniel R. Deaver, each having co-authored multiple publications with Bartus.

Publications have appeared in scientific journals and repositories including Brain, PLoS ONE, UNC Libraries, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • The Cholinergic Hypothesis of Geriatric Memory Dysfunction

    Raymond T. Bartus;Raymond T. Bartus;Reginald L. Dean;Bernard Beer;Bernard Beer;Arnold S. Lippa;Arnold S. Lippa

  • Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

    Jeffrey H. Kordower;C. Warren Olanow;Hemraj B. Dodiya;Yaping Chu

  • Age‐associated memory impairment: Proposed diagnostic criteria and measures of clinical change — report of a national institute of mental health work group

    Thomas Crook;Raymond T. Bartus;Steven H. Ferris;Peter J. Whitehouse

  • On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis.

    Raymond T. Bartus

  • Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

    William J Marks;Jill L Ostrem;Leonard Verhagen;Philip A Starr

  • Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial.

    William J Marks;Raymond T Bartus;Joao Siffert;Charles S Davis

  • The Cholinergic Hypothesis: A Historical Overview, Current Perspective, and Future Directions

    Raymond T. Bartus;Reginald L. Dean;Michael J. Pontecorvo;Charles Flicker

  • Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex in the rat.

    Charles Flicker;Reginald L. Dean;Dorothy L. Watkins;Stephen K. Fisher

  • Short-term memory in the rhesus monkey: disruption from the anti-cholinergic scopolamine.

    Raymond T. Bartus;H.R. Johnson

  • Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

    Keiro Ikeda;Tomotsugu Ichikawa;Hiroaki Wakimoto;Jonathan S. Silver

  • Aging in the rhesus monkey: debilitating effects on short-term memory.

    Raymond T. Bartus;Denise Fleming;H. R. Johnson

  • Age-related changes in passive avoidance retention: modulation with dietary choline.

    RT Bartus;RL Dean;JA Goas;AS Lippa

  • Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial.

    C. Warren Olanow;Raymond T. Bartus;Tiffany L. Baumann;Stewart Factor

  • Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat

    Kathryn E. Saatman;Hisayuki Murai;Raymond T. Bartus;Douglas H. Smith

  • Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.

    Jeffrey H. Kordower;Christopher D. Herzog;Biplob Dass;Roy A. E. Bakay

  • Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies.

    Raymond T. Bartus;Raymond T. Bartus;Charles Flicker;Reginald L. Dean;Michael Pontecorvo

  • Brain cholinergic dysfunction and memory in aged rats

    Arnold S. Lippa;Russell W. Pelham;Bernard Beer;Donald J. Critchett

  • Age-related alterations in the rodent brain cholinergic system and behavior

    R. Strong;P. Hicks;L. Hsu;R.T. Bartus

  • Age-related differences in behavior across the life span of the C57BL/6J mouse.

    Reginald L. Dean;Joseph Scozzafava;J. Allen Goas;Barbara Regan

  • Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration.

    R T Bartus;N J Hayward;P J Elliott;S D Sawyer

Frequent Co-Authors

Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Steven H. Ferris
Steven H. Ferris New York University
Thomas H. Crook
Thomas H. Crook National Institutes of Health
C. Warren Olanow
C. Warren Olanow Icahn School of Medicine at Mount Sinai
Nicholas M. Boulis
Nicholas M. Boulis Emory University
Yaping Chu
Yaping Chu Rush University Medical Center
Mark H. Tuszynski
Mark H. Tuszynski University of California, San Diego
Eugene M. Johnson
Eugene M. Johnson Washington University in St. Louis
Roy A.E. Bakay
Roy A.E. Bakay Rush University Medical Center
Brant P. Hasler
Brant P. Hasler University of Pittsburgh

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