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Neuroscience

D-Index
46
Citations
12892
World Ranking
6583
National Ranking
2855

Overview

Yaping Chu is a researcher affiliated with Rush University Medical Center in the United States. Their work primarily focuses on the fields of Medicine and Neuroscience, with significant contributions to the subfields of Neurology, Cellular and Molecular Neuroscience, Molecular Biology, Physiology, and Cell Biology.

The main topics explored in Chu's research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Nerve injury and regeneration
  • Genetic Neurodegenerative Diseases
  • Alzheimer's disease research and treatments
  • RNA Interference and Gene Delivery
  • Biotin and Related Studies

Chu has authored several research papers, among which the notable publications are:

  • "Nigrostriatal tau pathology in parkinsonism and Parkinson's disease," 2023, published in Brain
  • "Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease," 2020, published in Brain
  • "GDNF signaling in subjects with minimal motor deficits and Parkinson's disease," 2021, published in Neurobiology of Disease

In collaboration, Chu has frequently worked with several co-authors, including:

  • Jeffrey H. Kordower
  • Bryan A. Killinger
  • Solji Choi
  • Tyler Tittle

Publishers and venues that have frequently featured Chu's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Zenodo (CERN European Organization for Nuclear Research)
  • Proceedings of the National Academy of Sciences
  • npj Parkinson s Disease

Best Publications

  • Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

    Jeffrey H Kordower;Yaping Chu;Robert A Hauser;Thomas B Freeman

  • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

    Jeffrey H. Kordower;Marina E. Emborg;Jocelyne Bloch;Shuang Y. Ma

  • Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

    Jeffrey H. Kordower;C. Warren Olanow;Hemraj B. Dodiya;Yaping Chu

  • Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.

    Jeffrey H. Kordower;Yaping Chu;Glenn T. Stebbins;Steven T. DeKosky

  • Age-associated increases of α-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

    Yaping Chu;Jeffrey H. Kordower

  • Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

    Yaping Chu;Hemraj Dodiya;Patrick Aebischer;C. Warren Olanow

  • Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease.

    Dwaine F. Emerich;Shelley R. Winn;Philippe M. Hantraye;Marc Peschanski

  • Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

    Yaping Chu;Gerardo A. Morfini;Lori B. Langhamer;Yinzhen He

  • Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.

    William P. Flavin;Luc Bousset;Zachary C. Green;Yaping Chu

  • Transplanted dopaminergic neurons develop PD pathologic changes: A second case report

    Jeffrey H. Kordower;Yaping Chu;Robert A. Hauser;C.Warren Olanow

  • Nurr1 in Parkinson’s disease and related disorders

    Yaping Chu;Weidong Le;Katie Kompoliti;Joseph Jankovic

  • Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra.

    Yaping Chu;Katie Kompoliti;Elizabeth J. Cochran;Elliott J. Mufson

  • Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration

    Stephane Palfi;Stephane Palfi;Liza Leventhal;Yaping Chu;Shuang Y. Ma

  • Lentiviral gene transfer to the nonhuman primate brain.

    Jeffrey H Kordower;Jocelyne Bloch;Shuang Y Ma;Yaping Chu

  • A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease.

    Michael S. Rafii;Tiffany L. Baumann;Roy A. E. Bakay;Jeffrey M. Ostrove

  • Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

    F. Cicchetti;S. Saporta;R. A. Hauser;M. Parent

  • Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: Diminished compensatory mechanisms as a prelude to parkinsonism

    Timothy J. Collier;Jack Lipton;Brian F. Daley;Stephane Palfi

  • Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains

    Raymond T. Bartus;Christopher D. Herzog;Yaping Chu;Alistair Wilson

  • Proteasome inhibition and Parkinson's disease modeling.

    Jordi Bové;Chun Zhou;Vernice Jackson-Lewis;Julie Taylor

  • Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

    Jeffrey H. Kordower;Nicholas M. Kanaan;Yaping Chu;Rangasamy Suresh Babu

Frequent Co-Authors

Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Roy A.E. Bakay
Roy A.E. Bakay Rush University Medical Center
Patrick Aebischer
Patrick Aebischer École Polytechnique Fédérale de Lausanne
Elliott J. Mufson
Elliott J. Mufson Barrow Neurological Institute
Xiao-Xin Yan
Xiao-Xin Yan Central South University
Dwaine F. Emerich
Dwaine F. Emerich Alkermes (Ireland)
Peter R. Patrylo
Peter R. Patrylo Southern Illinois University School of Medicine
Caryl E. Sortwell
Caryl E. Sortwell Michigan State University
Jocelyne Bloch
Jocelyne Bloch University of Lausanne
Huaibin Cai
Huaibin Cai National Institutes of Health

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