World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12229
World Ranking
14360
National Ranking
393

Overview

Dagmar Wilhelm is affiliated with the University of Melbourne in Australia and has focused research efforts in the intersecting fields of biochemistry, genetics, molecular biology, and medicine. Their scientific work spans topics related to sex determination, reproductive biology, and molecular pathways involved in gonadal development and function.

Their research extensively covers the genetic and clinical aspects of sex determination and chromosomal abnormalities, with additional emphasis on sperm and testicular function, sexual differentiation and disorders, and the ubiquitin and proteasome pathways. Further topics addressed include reproductive biology and fertility, testicular diseases and treatments, and prostate cancer treatment and research.

Recent scholarly contributions by Dagmar Wilhelm include the following publications:

  • Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad, 2022, Science Advances
  • TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway, 2022, Nature Communications
  • The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice, 2020, PLoS ONE
  • β-hydroxybutyrate reduces blastocyst viability via trophectoderm-mediated metabolic aberrations in mice, 2022, Human Reproduction
  • Heterozygous deletion of Sox9 in mouse mimics the gonadal sex reversal phenotype associated with campomelic dysplasia in humans, 2020, Human Molecular Genetics

Publication venues where Dagmar Wilhelm has frequently contributed include bioRxiv (Cold Spring Harbor Laboratory), Science Advances, Nature Communications, Development, and Human Reproduction. Their work has also been featured in a book published by Frontiers Media titled Proceedings of the 9th International Symposium on the Biology of Vertebrate Sex Determination 2023, published in 2024.

Collaborations form a significant part of their research activities. Frequent co-authors include:

  • Serge Nef
  • Yasmine Neirijnck
  • Simon P. Windley
  • Chloé Mayère
  • Marie-Christine Chaboissier

Dagmar Wilhelm's work is marked by contributions to advancing understanding in molecular biology and genetics, particularly in the areas related to reproductive health, sexual differentiation, and developmental biology of the gonads. Their multidisciplinary approach integrates molecular techniques with clinical and developmental insights relevant to reproductive medicine and related biomedical fields.

Best Publications

  • Retinoid Signaling Determines Germ Cell Fate in Mice

    Josephine Bowles;Deon Knight;Christopher Smith;Dagmar Wilhelm

  • Sex Determination and Gonadal Development in Mammals

    Dagmar Wilhelm;Stephen Palmer;Peter A Koopman

  • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

    H. Van Dam;D. Wilhelm;I. Herr;A. Steffen

  • Sox18 induces development of the lymphatic vasculature in mice

    Mathias Francois;Andrea Caprini;Brett Hosking;Fabrizio Orsenigo

  • Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

    Andrew J. Bannister;Thomas Oehler;Thomas Oehler;Dagmar Wilhelm;Peter Angel

  • Activation of CD95 (APO‐1/Fas) signaling by ceramide mediates cancer therapy‐induced apoptosis

    Ingrid Herr;Dagmar Wilhelm;Thomas Böhler;Peter Angel

  • The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1

    Dagmar Wilhelm;Christoph Englert

  • The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents.

    Dagmar Wilhelm;Klaus Bender;Axel Knebel;Peter Angel

  • Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

    Dagmar Wilhelm;Fred Martinson;Stephen Bradford;Megan J. Wilson

  • Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a.

    Shunsuke Kuroki;Shogo Matoba;Mika Akiyoshi;Yasuko Matsumura

  • Expression of distinct RNAs from 3′ untranslated regions

    Tim R. Mercer;Dagmar Wilhelm;Marcel E. Dinger;Giulia Soldà

  • SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development.

    Dagmar Wilhelm;Ryuji Hiramatsu;Hirofumi Mizusaki;Laura Widjaja

  • A critical time window of Sry action in gonadal sex determination in mice.

    Ryuji Hiramatsu;Shogo Matoba;Masami Kanai-Azuma;Naoki Tsunekawa

  • The makings of maleness: towards an integrated view of male sexual development.

    Dagmar Wilhelm;Peter A Koopman

  • Sox genes and cancer.

    C Dong;D Wilhelm;P Koopman

  • Endothelial cell migration directs testis cord formation.

    Alexander N. Combes;Dagmar Wilhelm;Tara Davidson;Elisabetta Dejana

  • SOX8 Is Expressed during Testis Differentiation in Mice and Synergizes with SF1 to Activate the Amh Promoter in Vitro

    Goslik Schepers;Megan Wilson;Dagmar Wilhelm;Peter Koopman

  • Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development

    Juan Carlos Polanco;Dagmar Wilhelm;Tara-Lynne Davidson;Deon Knight

  • The Wilms' tumor gene Wt1 is required for normal development of the retina.

    Kay-Dietrich Wagner;Nicole Wagner;Valerie P.I. Vidal;Valerie P.I. Vidal;Gunnar Schley

  • Novel PCR assay for determining the genetic sex of mice.

    Lindsey McFarlane;Vy Truong;James S Palmer;Dagmar Wilhelm

Frequent Co-Authors

Peter Koopman
Peter Koopman University of Queensland
Andrew H. Sinclair
Andrew H. Sinclair University of Melbourne
Vincent R. Harley
Vincent R. Harley Hudson Institute of Medical Research
Peter Angel
Peter Angel Karlsruhe Institute of Technology
Andreas Schedl
Andreas Schedl Grenoble Alpes University
Serge Nef
Serge Nef University of Geneva
Josephine Bowles
Josephine Bowles University of Queensland
Manfred Schartl
Manfred Schartl University of Würzburg
Marcel E. Dinger
Marcel E. Dinger University of Sydney
John S. Mattick
John S. Mattick University of New South Wales

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Dagmar Wilhelm

Trending Scientists

Recently Published Articles