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Emmanuel Planel

Emmanuel Planel

D-Index & Metrics

Neuroscience

D-Index
49
Citations
9638
World Ranking
5951
National Ranking
344

Overview

Emmanuel Planel is a researcher affiliated with Université Laval in Canada. Their primary research focus lies within Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology, with a significant body of work related to Alzheimer's disease and neurodegenerative disorders.

The scientist's main fields of study encompass:

  • Neuroscience
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specific subfields of research include:

  • Physiology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems
  • Cognitive Neuroscience

Emmanuel Planel has contributed extensively to research topics such as:

  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Adipose Tissue and Metabolism
  • Mitochondrial Function and Pathology
  • Stress Responses and Cortisol
  • Genetic Neurodegenerative Diseases
  • Circadian rhythm and melatonin

Their recent published papers include the following:

  • "Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways," 2022, Epilepsia
  • "Metabolic determinants of Alzheimer's disease: A focus on thermoregulation," 2021, Ageing Research Reviews
  • "Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model," 2021, Alzheimer's Research & Therapy
  • "Passive immunization against phosphorylated tau improves features of Huntington's disease pathology," 2022, Molecular Therapy
  • "Intranasal Administration of Nanovectorized Docosahexaenoic Acid (DHA) Improves Cognitive Function in Two Complementary Mouse Models of Alzheimer's Disease," 2022, Antioxidants

Frequent collaborators with whom Emmanuel Planel has coauthored multiple publications include:

  • Geoffrey Canet
  • Sébastien S. Hébert
  • Frédéric Calon
  • Séréna Petry
  • Emma Rocaboy

The scientist's research has been disseminated across various publication venues, with notable frequency in:

  • Frontiers in Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Methods in molecular biology
  • Epilepsia
  • Ageing Research Reviews

Best Publications

  • Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia

    Emmanuel Planel;Karl E. G. Richter;Charles E. Nolan;James E. Finley

  • Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

    Sébastien S. Hébert;Sébastien S. Hébert;Aikaterini S. Papadopoulou;Pascal Smith;Marie-Christine Galas;Marie-Christine Galas

  • Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

    Yoshitaka Tatebayashi;Tomohiro Miyasaka;De-Hua Chui;Takumi Akagi

  • Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease

    Emmanuel Planel;Tomohiro Miyasaka;Thomas Launey;De Hua Chui

  • Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar

    V. Jevtovic-Todorovic;A. R. Absalom;K. Blomgren;A. Brambrink

  • Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms

    Emmanuel Planel;Yoshitaka Tatebayashi;Tomohiro Miyasaka;Li Liu

  • Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation

    Alim Muhammad;Ingrid Flores;Hong Zhang;Rui Yu

  • Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse

    Emmanuel Planel;Kaori Yasutake;Shinobu C. Fujita;Koichi Ishiguro

  • A neuronal microtubule-interacting agent, NAPVSIPQ, reduces tau pathology and enhances cognitive function in a mouse model of Alzheimer's disease.

    Yasuji Matsuoka;Yan Jouroukhin;Audrey J. Gray;Li Ma

  • Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease

    Milene Vandal;Phillip J. White;Cyntia Tremblay;Isabelle St-Amour;Isabelle St-Amour

  • miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

    Pascal Y. Smith;Julia Hernandez-Rapp;Francis Jolivette;Cynthia Lecours

  • Transcriptional Regulation of β-Secretase by p25/cdk5 Leads to Enhanced Amyloidogenic Processing

    Yi Wen;W. Haung Yu;Bryan Maloney;Jason Bailey

  • Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3β Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precursor Protein Processing

    Yi Wen;Emmanuel Planel;Mathieu Herman;Helen Y. Figueroa

  • Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-Synuclein

    Wai Haung Yu;Beatriz Dorado;Helen Yvette Figueroa;Lili Wang

  • Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD).

    Mohammed Filali;Robert Lalonde;Peter Theriault;Carl Julien

  • MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy

    Pascal Y. Smith;Charlotte Delay;Johanne Girard;Marie-Amélie Papon

  • Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia

    Emmanuel Planel;Alexis Bretteville;Li Liu;Laszlo Virag

  • Propofol Directly Increases Tau Phosphorylation

    Robert A. Whittington;László Virág;François Marcouiller;Marie-Amélie Papon

  • Insulin dysfunction and Tau pathology

    Noura B. El Khoury;Maud Gratuze;Marie-Amélie Papon;Alexis Bretteville

  • U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.

    Shigetsugu Hatakeyama;Masaki Matsumoto;Takumi Kamura;Miyuki Murayama

Frequent Co-Authors

Frédéric Calon
Frédéric Calon Université Laval
Karen Duff
Karen Duff University College London
Francesca Cicchetti
Francesca Cicchetti Université Laval
Ottavio Arancio
Ottavio Arancio Columbia University
Tsutomu Hashikawa
Tsutomu Hashikawa RIKEN Center for Brain Science
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria
Mike Hutton
Mike Hutton Eli Lilly (United States)
Barry Ganetzky
Barry Ganetzky University of Wisconsin–Madison

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