World's Best Scientists 2026 revealed!
Cecilia Hidalgo

Cecilia Hidalgo

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
8872
World Ranking
13465
National Ranking
16

Overview

Cecilia Hidalgo is affiliated with the University of Chile in Chile and has a research profile primarily focused on biochemistry, genetics, molecular biology, medicine, and neuroscience. Their work spans various topics within these fields, including cellular and molecular neuroscience and physiology, with a notable concentration in molecular biology research.

Their research interests cover multiple specialized areas such as neuroscience and neuropharmacology, ion channel regulation and function, mitochondrial function and pathology, nicotinic acetylcholine receptor studies, ferroptosis and cancer prognosis, Alzheimer's disease research and treatments, and the inflammasome and immune disorders.

Recent publications include:

  • The calcium-iron connection in ferroptosis-mediated neuronal death (2021, Free Radical Biology and Medicine)
  • RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression (2021, Proceedings of the National Academy of Sciences)
  • Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation (2020, Marine Drugs)
  • Ryanodine Receptor Mediated Calcium Release Contributes to Ferroptosis Induced in Primary Hippocampal Neurons by GPX4 Inhibition (2023, Antioxidants)
  • Activation of the ROS/TXNIP/NLRP3 pathway disrupts insulin-dependent glucose uptake in skeletal muscle of insulin-resistant obese mice (2024, Free Radical Biology and Medicine)

Frequent coauthors associated with their work include Andrea Paula-Lima, Pedro Lobos, Silvia Gleitze, Ignacio Vega-Vásquez, and Tatiana Adasme.

Their research is commonly published in journals such as Free Radical Biology and Medicine, Antioxidants, Preprints.org, Trends in Molecular Medicine, and Cell Calcium. These publication venues reflect the interdisciplinary nature of their scientific inquiry, which bridges molecular and cellular neuroscience with oxidative stress and antioxidant studies.

Best Publications

  • Reconstitution in planar lipid bilayers of a Ca2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle

    Ramon Latorre;Cecilia Vergara;Cecilia Hidalgo

  • Immunological and biochemical properties of transverse tubule membranes isolated from rabbit skeletal muscle.

    M. Rosemblatt;C. Hidalgo;C. Vergara;N. Ikemoto

  • Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

    Valentina Parra;Veronica Eisner;Mario Chiong;Alfredo Criollo

  • Identification of Cysteines Involved in S-Nitrosylation, S-Glutathionylation, and Oxidation to Disulfides in Ryanodine Receptor Type 1

    Paula Aracena-Parks;Sanjeewa A. Goonasekera;Charles P. Gilman;Robert T. Dirksen

  • Sulfhydryl oxidation modifies the calcium dependence of ryanodine-sensitive calcium channels of excitable cells.

    Juan José Marengo;Cecilia Hidalgo;Cecilia Hidalgo;Ricardo Bull

  • Crosstalk between calcium and redox signaling: from molecular mechanisms to health implications.

    Cecilia Hidalgo;Paulina Donoso

  • A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.

    Cecilia Hidalgo;Gina Sánchez;Genaro Barrientos;Paula Aracena-Parks

  • Role of phospholipids in the calcium-dependent ATPase of the sarcoplasmic reticulum. Enzymatic and ESR studies with phospholipid-replaced membranes.

    C Hidalgo;N Ikemoto;J Gergely

  • Myotube depolarization generates reactive oxygen species through NAD(P)H oxidase; ROS-elicited Ca2+ stimulates ERK, CREB, early genes.

    Alejandra Espinosa;Aida Leiva;Marisol Peña;Mariolly Müller

  • Highly purified sarcoplasmic reticulum vesicles are devoid of Ca2+-independent (‘basal’) ATPase activity

    JoséL. Fernandez;Mario Rosemblatt;Cecilia Hidalgo

  • Effect of the lipid environment on protein motion and enzymatic activity of sarcoplasmic reticulum calcium ATPase.

    C. Hidalgo;David D Thomas;N. Ikemoto

  • Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.

    Andrea C. Paula-Lima;Tatiana Adasme;Carol SanMartín;Adriano Sebollela

  • Characterization of the Ca2+- or Mg2+-ATPase of transverse tubule membranes isolated from rabbit skeletal muscle.

    C Hidalgo;M E Gonzalez;R Lagos

  • Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation

    Tatiana Adasme;Paola Haeger;Andrea C. Paula-Lima;Italo Espinoza

  • Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle.

    Gina Sánchez;Zully Pedrozo;Raúl J. Domenech;Cecilia Hidalgo

  • Modulation of cardiac ryanodine receptor activity by ROS and RNS.

    Paulina Donoso;Gina Sanchez;Ricardo Bull;Cecilia Hidalgo

  • S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels.

    Paula Aracena;Gina Sánchez;Paulina Donoso;Susan L. Hamilton

  • Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection

    Gina Sánchez;Matías Escobar;Zully Pedrozo;Pilar Macho

  • Iron Mediates N-Methyl-d-aspartate Receptor-dependent Stimulation of Calcium-induced Pathways and Hippocampal Synaptic Plasticity

    Pablo Muñoz;Alexis Humeres;Claudio Elgueta;Alfredo Kirkwood

  • Effects of S-glutathionylation and S-nitrosylation on calmodulin binding to triads and FKBP12 binding to type 1 calcium release channels.

    Paula Aracena;Wei Tang;Susan L. Hamilton;Cecilia Hidalgo

Frequent Co-Authors

Marco T. Núñez
Marco T. Núñez University of Chile
Sergio Lavandero
Sergio Lavandero University of Chile
David D. Thomas
David D. Thomas University of Minnesota
Susan L. Hamilton
Susan L. Hamilton Baylor College of Medicine
Rosario Rizzuto
Rosario Rizzuto University of Padua
Michel De Waard
Michel De Waard University of Nantes
Alfredo Criollo
Alfredo Criollo University of Chile
Alfredo Kirkwood
Alfredo Kirkwood Johns Hopkins University
Amira Klip
Amira Klip University of Toronto
James Williams
James Williams Australian National University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Cecilia Hidalgo

Trending Scientists