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Biology and Biochemistry

D-Index
61
Citations
13128
World Ranking
11364
National Ranking
306

Overview

Graham D. Lamb is a researcher affiliated with La Trobe University in Australia. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology as a subfield. The research contributions include topics related to Muscle Physiology and Disorders, Ion Channel Regulation and Function, and Cardiac Electrophysiology and Arrhythmias, among others.

The scientist's recent publications reflect a concentration on muscle physiology, ion channel dynamics, and exercise-related physiological responses. Notable papers include:

  • Effects of high-intensity intermittent exercise on the contractile properties of human type I and type II skeletal muscle fibers, 2020, Journal of Applied Physiology
  • Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor, 2024, Nature Communications
  • Expression of titin-linked putative mechanosensing proteins in skeletal muscle after power resistance exercise in resistance-trained men, 2020, Journal of Applied Physiology
  • Nuclei isolation methods fail to accurately assess the subcellular localization and behaviour of proteins in skeletal muscle, 2021, Acta Physiologica
  • Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation, 2020, American Journal of Physiology-Cell Physiology

Their research has been published in several scientific venues, with multiple papers appearing in the Journal of Applied Physiology. Other frequent venues include Nature Communications, Acta Physiologica, International Journal of Molecular Sciences, and the American Journal of Physiology-Cell Physiology.

Graham D. Lamb collaborates regularly with a core group of coauthors. Frequent collaborators include Robyn M. Murphy, Stefan G. Wette, C. R. Lamboley, David Rouffet, and Michael J. McKenna. These partnerships suggest ongoing projects and shared research interests in muscle physiology and molecular mechanisms underlying muscular function and adaptation.

The scientist's main topics of research encompass:

  • Muscle Physiology and Disorders
  • Ion Channel Regulation and Function
  • Cardiac Electrophysiology and Arrhythmias
  • Exercise and Physiological Responses
  • Adipose Tissue and Metabolism
  • Muscle Activation and Electromyography Studies
  • Mass Spectrometry Techniques and Applications

The subfields of study related to their work include Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Rehabilitation, and Physiology.

Best Publications

  • Skeletal Muscle Fatigue: Cellular Mechanisms

    D. G. Allen;G. D. Lamb;H. Westerblad

  • Intracellular Acidosis Enhances the Excitability of Working Muscle

    Thomas H. Pedersen;Ole B. Nielsen;Graham D. Lamb;D. George Stephenson

  • Effects of creatine phosphate and P(i) on Ca2+ movements and tension development in rat skinned skeletal muscle fibres.

    M W Fryer;V J Owen;G D Lamb;D G Stephenson

  • Impaired calcium release during fatigue

    David G. Allen;Graham D. Lamb;Hakan Westerblad

  • Neural mechanisms of spatial tactile discrimination: neural patterns evoked by braille‐like dot patterns in the monkey.

    K O Johnson;G D Lamb

  • Effects of intracellular pH and [Mg2+] on excitation-contraction coupling in skeletal muscle fibres of the rat.

    G D Lamb;D G Stephenson

  • Raised intracellular [Ca2+] abolishes excitation‐contraction coupling in skeletal muscle fibres of rat and toad.

    G D Lamb;P R Junankar;D G Stephenson

  • Excitation-contraction coupling in skeletal muscle: comparisons with cardiac muscle.

    Lamb Gd

  • Effect of Mg2+ on the control of Ca2+ release in skeletal muscle fibres of the toad.

    G D Lamb;D G Stephenson

  • Events of the excitation–contraction–relaxation (E–C–R) cycle in fast- and slow-twitch mammalian muscle fibres relevant to muscle fatigue

    D. G. Stephenson;G. D. Lamb;G. M. M. Stephenson

  • Acute effects of reactive oxygen and nitrogen species on the contractile function of skeletal muscle

    Graham D. Lamb;Håkan Westerblad

  • Calsequestrin content and SERCA determine normal and maximal Ca2+ storage levels in sarcoplasmic reticulum of fast- and slow-twitch fibres of rat

    Robyn M. Murphy;Noni T. Larkins;Janelle P. Mollica;Nicole A. Beard

  • Calcium release in skinned muscle fibres of the toad by transverse tubule depolarization or by direct stimulation.

    G D Lamb;D G Stephenson

  • Important considerations for protein analyses using antibody based techniques: down-sizing Western blotting up-sizes outcomes

    Robyn M. Murphy;Graham D. Lamb

  • Effects of carnosine on contractile apparatus Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in human skeletal muscle fibers

    Travis Luke Dutka;Cedric R. Lamboley;Michael John McKenna;Robyn M. Murphy

  • Calcium currents, charge movement and dihydropyridine binding in fast- and slow-twitch muscles of rat and rabbit.

    G D Lamb;T Walsh

  • Different Ca2+ releasing action of caffeine and depolarisation in skeletal muscle fibres of the rat

    Graham Douglas. Lamb;Maria. Cellini;Dimitrie George. Stephenson

  • Ca2+ activation of diffusible and bound pools of μ-calpain in rat skeletal muscle

    Robyn M. Murphy;Esther Verburg;Graham D. Lamb

  • Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle.

    R. M. Murphy;T. L. Dutka;D. Horvath;J. R. Bell

  • Effect of Carnosine on Excitation–Contraction Coupling in Mechanically-Skinned Rat Skeletal Muscle

    Travis L. Dutka;Graham D. Lamb

Frequent Co-Authors

D. G. Stephenson
D. G. Stephenson La Trobe University
Michael J. McKenna
Michael J. McKenna Massachusetts Eye and Ear Infirmary
Angela F. Dulhunty
Angela F. Dulhunty Australian National University
Håkan Westerblad
Håkan Westerblad Karolinska Institute
Peter W. Gage
Peter W. Gage Australian National University
David G. Allen
David G. Allen University of Sydney
Istvan Toth
Istvan Toth University of Queensland
Robert H. Fitts
Robert H. Fitts Marquette University
David Stapleton
David Stapleton Florey Institute of Neuroscience and Mental Health
Isabelle Richard
Isabelle Richard Centre national de la recherche scientifique, CNRS

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