Elisabetta Ciani

Overview

Best Publications

• Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.

  Sandra Guidi;Paola Bonasoni;Claudio Ceccarelli;Donatella Santini

  330
  Citations

• Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.

  Andrea Contestabile;Tatiana Fila;Claudio Ceccarelli;Paola Bonasoni

  321
  Citations

• Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

  Patrizia Bianchi;Elisabetta Ciani;Sandra Guidi;Stefania Trazzi

  247
  Citations

• Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation.

  Antonio Contestabile;Elisabetta Ciani

  220
  Citations

• hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer.

  A. Varrault;E. Ciani;F. Apiou;B. Bilanges

  211
  Citations

• Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder

  Elena Amendola;Yang Zhan;Camilla Mattucci;Enrico Castroflorio

  206
  Citations

• Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide.

  Elisabetta Ciani;Sandra Guidi;Renata Bartesaghi;Antonio Contestabile

  200
  Citations

• Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

  Sandra Guidi;Elisabetta Ciani;Paola Bonasoni;Donatella Santini

  182
  Citations

• Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

  Claudia Fuchs;Stefania Trazzi;Roberta Torricella;Rocchina Viggiano

  159
  Citations

• Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons.

  Elisabetta Ciani;Lena Grøneng;Manuela Voltattorni;Veslemøy Rolseth

  144
  Citations

• Timing of therapies for Down syndrome: the sooner, the better.

  Fiorenza Stagni;Andrea Giacomini;Sandra Guidi;Elisabetta Ciani

  135
  Citations

• APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

  Stefania Trazzi;Valentina Maria Mitrugno;Emanuele Valli;Claudia Fuchs

  135
  Citations

• Brain Nitric Oxide and Its Dual Role in Neurodegeneration / Neuroprotection: Understanding Molecular Mechanisms to Devise Drug Approaches

  Antonio Contestabile;Barbara Monti;Andrea Contestabile;Elisabetta Ciani

  127
  Citations

• Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones.

  Elisabetta Ciani;Marco Virgili;Antonio Contestabile

  122
  Citations

• HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.

  Stefania Trazzi;Claudia Fuchs;Rocchina Viggiano;Marianna De Franceschi

  117
  Citations

• Nitric Oxide Protects Neuroblastoma Cells from Apoptosis Induced by Serum Deprivation through cAMP-response Element-binding Protein (CREB) Activation

  Elisabetta Ciani;Sandra Guidi;Giuliano Della Valle;Giovanni Perini

  108
  Citations

• Transcriptional Activities of the Zinc Finger Protein Zac Are Differentially Controlled by DNA Binding

  Anke Hoffmann;Elisabetta Ciani;Joel Boeckardt;Florian Holsboer

  105
  Citations

• Is it possible to improve neurodevelopmental abnormalities in Down syndrome

  Renata Bartesaghi;Sandra Guidi;Elisabetta Ciani

  104
  Citations

• Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome.

  Patrizia Bianchi;Elisabetta Ciani;Andrea Contestabile;Sandra Guidi

  103
  Citations

• Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801

  F. Facchinetti;E. Ciani;R. Dall'Olio;M. Virgili

  100
  Citations