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Renata Bartesaghi

Renata Bartesaghi

D-Index & Metrics

Neuroscience

D-Index
37
Citations
5290
World Ranking
8814
National Ranking
483

Overview

Renata Bartesaghi is affiliated with the University of Bologna in Italy and conducts research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their scientific work focuses largely on the study of Down syndrome and intellectual disability, genetics and neurodevelopmental disorders, and treatments related to Alzheimer's disease. Additional research interests include cerebral palsy and movement disorders, neurogenesis and neuroplasticity mechanisms, nerve injury and regeneration, and connective tissue disorders.

The main topics covered in their research include:

  • Down syndrome and intellectual disability research
  • Genetics and neurodevelopmental disorders
  • Alzheimer's disease research and treatments
  • Cerebral palsy and movement disorders
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Connective tissue disorders research

Frequent publication venues for Bartesaghi's work span several specialized journals, with multiple papers appearing in the Journal of Biological Chemistry and Neurobiology of Disease. Other venues include the Journal of Nutrition, Critical Reviews in Food Science and Nutrition, and Frontiers in Cellular Neuroscience.

They have contributed to significant papers such as:

  • "Brain circuit pathology in Down syndrome: from neurons to neural networks" (2022) published in Reviews in the Neurosciences
  • "The Challenging Pathway of Treatment for Neurogenesis Impairment in Down Syndrome: Achievements and Perspectives" (2022) published in Frontiers in Cellular Neuroscience
  • "Treatment with the flavonoid 7,8-Dihydroxyflavone: a promising strategy for a constellation of body and brain disorders" (2020) published in Critical Reviews in Food Science and Nutrition
  • "Prenatal Administration of Oleic Acid or Linolenic Acid Reduces Neuromorphological and Cognitive Alterations in Ts65dn Down Syndrome Mice" (2020) published in Journal of Nutrition
  • "Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome" (2020) published in Clinical Neurology and Neurosurgery

Bartesaghi frequently collaborates with fellow researchers including Sandra Guidi, Fiorenza Stagni, Marco Emili, Beatrice Uguagliati, and Andrea Giacomini. These collaborations have resulted in multiple co-authored publications contributing to their fields of interest.

Their subfields of study further detail their research focus areas and include Public Health, Environmental and Occupational Health, Molecular Biology, Genetics, Physiology, and Pediatrics, Perinatology, and Child Health.

Best Publications

  • Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood.

    Tiziana Rubino;Natalia Realini;Daniela Braida;Sandra Guidi

  • Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.

    Sandra Guidi;Paola Bonasoni;Claudio Ceccarelli;Donatella Santini

  • Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.

    Andrea Contestabile;Tatiana Fila;Claudio Ceccarelli;Paola Bonasoni

  • Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

    Patrizia Bianchi;Elisabetta Ciani;Sandra Guidi;Stefania Trazzi

  • Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide.

    Elisabetta Ciani;Sandra Guidi;Renata Bartesaghi;Antonio Contestabile

  • Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

    Sandra Guidi;Elisabetta Ciani;Paola Bonasoni;Donatella Santini

  • Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

    Claudia Fuchs;Stefania Trazzi;Roberta Torricella;Rocchina Viggiano

  • Timing of therapies for Down syndrome: the sooner, the better.

    Fiorenza Stagni;Andrea Giacomini;Sandra Guidi;Elisabetta Ciani

  • APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

    Stefania Trazzi;Valentina Maria Mitrugno;Emanuele Valli;Claudia Fuchs

  • HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.

    Stefania Trazzi;Claudia Fuchs;Rocchina Viggiano;Marianna De Franceschi

  • Neurogenesis impairment: An early developmental defect in Down syndrome.

    Fiorenza Stagni;Andrea Giacomini;Marco Emili;Sandra Guidi

  • Nitric Oxide Protects Neuroblastoma Cells from Apoptosis Induced by Serum Deprivation through cAMP-response Element-binding Protein (CREB) Activation

    Elisabetta Ciani;Sandra Guidi;Giuliano Della Valle;Giovanni Perini

  • Is it possible to improve neurodevelopmental abnormalities in Down syndrome

    Renata Bartesaghi;Sandra Guidi;Elisabetta Ciani

  • Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome.

    Patrizia Bianchi;Elisabetta Ciani;Andrea Contestabile;Sandra Guidi

  • Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation

    Elisabetta Ciani;Sabina Severi;Andrea Contestabile;Renata Bartesaghi

  • Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model

    Sandra Guidi;Fiorenza Stagni;Patrizia Bianchi;Elisabetta Ciani

  • Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder.

    Claudia Fuchs;Roberto Rimondini;Rocchina Viggiano;Stefania Trazzi

  • Treatment with the flavonoid 7,8-Dihydroxyflavone: a promising strategy for a constellation of body and brain disorders.

    Marco Emili;Sandra Guidi;Beatrice Uguagliati;Andrea Giacomini

  • Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome.

    Andrea Contestabile;Tatiana Fila;Renata Bartesaghi;Elisabetta Ciani

  • CB1 Cannabinoid Receptors Increase Neuronal Precursor Proliferation through AKT/Glycogen Synthase Kinase-3β/β-Catenin Signaling

    Stefania Trazzi;Martin Steger;Valentina Maria Mitrugno;Renata Bartesaghi

Frequent Co-Authors

Elisabetta Ciani
Elisabetta Ciani University of Bologna
Roberto Rimondini
Roberto Rimondini University of Bologna
Antonio Contestabile
Antonio Contestabile University of Bologna
Laura Calzà
Laura Calzà University of Bologna
Yann Herault
Yann Herault Institute of Genetics and Molecular and Cellular Biology
Michele Migliore
Michele Migliore National Academies of Sciences, Engineering, and Medicine
Mara Dierssen
Mara Dierssen Centre for Genomic Regulation
Tommaso Pizzorusso
Tommaso Pizzorusso University of Florence
Tarik F. Haydar
Tarik F. Haydar Boston University
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva

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