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Genetics

D-Index
65
Citations
16493
World Ranking
2692
National Ranking
1183

Overview

Roger H. Reeves is affiliated with Johns Hopkins University School of Medicine in the United States. Their research principally spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on genetics-related issues.

The scientist's work covers several subfields, including Genetics, Public Health, Environmental and Occupational Health, Molecular Biology, Surgery, and Epidemiology. Their main topics of interest revolve around Down syndrome and intellectual disability research, Genetics and Neurodevelopmental Disorders, Genomic variations and chromosomal abnormalities, Hedgehog Signaling Pathway Studies, Chronic Disease Management Strategies, Autism Spectrum Disorder Research, as well as Genomics and Rare Diseases.

Roger H. Reeves has published multiple papers in a variety of scientific journals. Recent significant publications include:

  • Down syndrome, 2020, Nature Reviews Disease Primers
  • A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21, 2020, eLife
  • Opportunities, barriers, and recommendations in Down syndrome research, 2021, Translational Science of Rare Diseases
  • All Creatures Great and Small: New Approaches for Understanding Down Syndrome Genetics, 2020, Trends in Genetics
  • A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features, 2022, The American Journal of Human Genetics

Throughout their career, Roger H. Reeves has collaborated frequently with other researchers. Common coauthors include:

  • Feng Gao
  • Yasuhiro Kazuki
  • Anna J. Moyer
  • Mitsuo Oshimura
  • Yicong Li

They have contributed to a number of academic venues, with the most frequent publication platforms being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Yale Review
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • eLife
  • The FASEB Journal

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • A mouse model for Down syndrome exhibits learning and behaviour deficits

    Roger H. Reeves;Nicholas G. Irving;Timothy H. Moran;Anny Wohn

  • TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer.

    Masami Kuramochi;Hiroshi Fukuhara;Takahiro Nobukuni;Takamasa Kanbe

  • Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin.

    Eloisa S. Moreira;Tim J. Wiltshire;Georgine Faulkner;Antje Nilforoushan

  • Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

    Kwan Hyuck Baek;Alexander Zaslavsky;Ryan C. Lynch;Carmella Britt

  • Segmental trisomy as a mouse model for Down syndrome.

    M T Davisson;C Schmidt;R H Reeves;N G Irving

  • A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

    Lisa Olson;Joan T Richtsmeier;J Leszl;Roger H Reeves

  • Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse

    Laura L. Baxter;Timothy H. Moran;Joan T. Richtsmeier;Juan Troncoso

  • Parallels of Craniofacial Maldevelopment in Down Syndrome and Ts65Dn Mice

    Joan T. Richtsmeier;Laura L. Baxter;Roger H. Reeves

  • Transcript Level Alterations Reflect Gene Dosage Effects Across Multiple Tissues in a Mouse Model of Down Syndrome

    Pascal Kahlem;Marc Sultan;Ralf Herwig;Matthias Steinfath

  • Understanding the Basis for Down Syndrome Phenotypes

    Randall J Roper;Roger H Reeves

  • Down syndrome and Alzheimer's disease: Common pathways, common goals.

    Dean Hartley;Thomas Blumenthal;Maria Carrillo;Gilbert DiPaolo

  • The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation

    Sally A. Camper;Thomas L. Saunders;Ronald W. Katz;Roger H. Reeves

  • Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice.

    Roger H. Reeves;Jibin Yao;Michael R. Crowley;Michael R. Crowley;Suzanne Buck

  • Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice

    Randall J. Roper;Laura L. Baxter;Nidhi G. Saran;Donna K. Klinedinst

  • The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome.

    Nadia P. Belichenko;Pavel V. Belichenko;Alexander M. Kleschevnikov;Ahmad Salehi

  • Trisomy for the Down syndrome ‘critical region’ is necessary but not sufficient for brain phenotypes of trisomic mice

    Lisa E. Olson;Randall J. Roper;Crystal L. Sengstaken;Elizabeth A. Peterson

  • Trisomy 21 and early brain development

    Tarik F. Haydar;Roger H. Reeves

  • Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes

    L. E. Olson;R. J. Roper;L. L. Baxter;E. J. Carlson

  • Too much of a good thing: mechanisms of gene action in Down syndrome

    Roger H Reeves;Laura L Baxter;Joan T Richtsmeier

Frequent Co-Authors

Joan T. Richtsmeier
Joan T. Richtsmeier Pennsylvania State University
John D. Gearhart
John D. Gearhart University of Pennsylvania
Stephanie L. Sherman
Stephanie L. Sherman Emory University
Joseph T. Coyle
Joseph T. Coyle Harvard University
Bruce F. O'Hara
Bruce F. O'Hara University of Kentucky
William J. Pavan
William J. Pavan National Institutes of Health
Katheleen Gardiner
Katheleen Gardiner University of Colorado Denver
Tim Wiltshire
Tim Wiltshire University of North Carolina at Chapel Hill
Yoshinori Murakami
Yoshinori Murakami University of Tokyo
Timothy H. Moran
Timothy H. Moran Johns Hopkins University School of Medicine

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