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Biology and Biochemistry

D-Index
55
Citations
38991
World Ranking
14724
National Ranking
6151

Overview

Alexandru Almasan is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research spans key areas within medicine and biochemistry, genetics, and molecular biology. The scientist's work focuses on subfields such as molecular biology, oncology, epidemiology, pulmonary and respiratory medicine, and genetics.

The research topics most frequently addressed by Alexandru Almasan include:

  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Autophagy in Disease and Therapy
  • Chronic Lymphocytic Leukemia Research
  • Ubiquitin and proteasome pathways
  • Cancer therapeutics and mechanisms
  • Microtubule and mitosis dynamics

Some of the recent papers published by Alexandru Almasan are:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), 2021, published in Autophagy
  • Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance, 2020, published in Cell Death and Disease
  • Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice, 2021, published in Science Translational Medicine
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), 2021, published in Americanae (AECID Library)
  • Nudix Hydrolase NUDT16 Regulates 53BP1 Protein by Reversing 53BP1 ADP-Ribosylation, 2020, published in Cancer Research

The frequent co-authors working with Alexandru Almasan include Ofer Reizes, Zihua Gong, Hagai Abeliovich, Abraham Acevedo-Arozena, and Khosrow Adeli, with multiple collaborative publications.

The main venues where Alexandru Almasan has published are:

  • Cancer Research
  • Cell Death and Disease
  • Nucleic Acids Research
  • UNC Libraries
  • Autophagy

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Histone H2AX phosphorylation: a marker for DNA damage.

    Arishya Sharma;Kamini Singh;Alexandru Almasan

  • Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy.

    Alexandru Almasan;Avi Ashkenazi

  • Caspase-3 Activation Is a Critical Determinant of Genotoxic Stress-Induced Apoptosis

    Gaurav S. Choudhary;Sayer Al-harbi;Alexandru Almasan

  • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis

    Alexandru Almasan;Yuxin Yin;Yuxin Yin;Ruth E. Kelly;Eva Y. H. P. Lee

  • MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.

    G. S. Choudhary;S. Al-Harbi;Suparna Mazumder;Brian T. Hill

  • Distinct stages of cytochrome c release from mitochondria: Evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis

    Q. Chen;B. Gong;Alexandru Almasan

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Apo2L/TRAIL and Bcl-2–related proteins regulate type I interferon–induced apoptosis in multiple myeloma

    Quan Chen;Bendi Gong;Ashraf S. Mahmoud-Ahmed;Aimin Zhou

  • Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity.

    Suzy A.A. Comhair;Weiling Xu;Sudakshina Ghosh;Frederik B.J.M. Thunnissen

  • The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.

    Q. Chen;Y. C. Chai;Suparna Mazumder;C. Jiang

  • Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide.

    Yanhua Zheng;Yong Shi;Changhai Tian;Chunsun Jiang

  • Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis

    Jia Qiu;Cynthia Tsien;Samjhana Thapalaya;Arvind Narayanan

  • DNA damage response and apoptosis.

    Dragos Plesca;Suparna Mazumder;Alexandru Almasan;Alexandru Almasan

  • Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance.

    Isha Kapoor;Juraj Bodo;Brian T. Hill;Eric D. Hsi

  • Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells.

    Bendi Gong;Alex Almasan

  • Apoptosis Induction in Prostate Cancer Cells and Xenografts by Combined Treatment with Apo2 Ligand/Tumor Necrosis Factor-related Apoptosis-inducing Ligand and CPT-11

    Subrata Ray;Alex Almasan

Frequent Co-Authors

Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Eric A. Klein
Eric A. Klein Cleveland Clinic
Warren D.W. Heston
Warren D.W. Heston Case Western Reserve University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Eric D. Hsi
Eric D. Hsi Cleveland Clinic

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