Bart Ghesquière

Overview

Best Publications

• Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

  Katrien De Bock;Maria Georgiadou;Sandra Schoors;Anna Kuchnio

  1426
  Citations

• A roadmap for interpreting 13 C metabolite labeling patterns from cells

  Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  695
  Citations

• Consensus guidelines for the use and interpretation of angiogenesis assays

  Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  612
  Citations

• Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

  Anna Rita Cantelmo;Lena Christin Conradi;Aleksandra Brajic;Jermaine Goveia

  582
  Citations

• Fatty acid carbon is essential for dNTP synthesis in endothelial cells

  Sandra Schoors;Ulrike Bruning;Rindert Missiaen;Karla C S Queiroz

  577
  Citations

• Tumour hypoxia causes DNA hypermethylation by reducing TET activity

  Bernard Thienpont;Jessica Steinbacher;Hui Zhao;Flora D’Anna

  575
  Citations

• Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

  Sandra Schoors;Katrien De Bock;Anna Rita Cantelmo;Maria Georgiadou

  538
  Citations

• Metabolism of stromal and immune cells in health and disease

  Bart Ghesquière;Brian W. Wong;Anna Kuchnio;Peter Carmeliet

  462
  Citations

• Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

  Mathias Wenes;Min Shang;Mario Di Matteo;Jermaine Goveia

  420
  Citations

• Tumor Vessel Normalization by Chloroquine Independent of Autophagy

  Hannelore Maes;Anna Kuchnio;Aleksandar Peric;Stijn Moens

  411
  Citations

• Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

  Mira M. Wouters;Dafne Balemans;Sander Van Wanrooy;James Dooley

  376
  Citations

• Metabolites released from apoptotic cells act as tissue messengers

  Christopher B. Medina;Parul Mehrotra;Sanja Arandjelovic;Justin S. A. Perry

  373
  Citations

• The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

  Pieter Mestdagh;Anna-Karin Bostrom;Francis Impens;Erik Fredlund;Erik Fredlund

  360
  Citations

• The role of fatty acid β-oxidation in lymphangiogenesis

  Brian W. Wong;Xingwu Wang;Annalisa Zecchin;Bernard Thienpont

  346
  Citations

• A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity

  Marlen Knobloch;Gregor-Alexander Pilz;Bart Ghesquière;Werner J. Kovacs

  334
  Citations

• Role of glutamine and interlinked asparagine metabolism in vessel formation

  Hongling Huang;Saar Vandekeere;Joanna Kalucka;Laura Bierhansl

  331
  Citations

• Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.

  Erika M. Palmieri;Marieli Gonzalez-Cotto;Walter A. Baseler;Luke C. Davies

  308
  Citations

• Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

  Erika M. Palmieri;Alessio Menga;Rosa Martín-Pérez;Annamaria Quinto

  295
  Citations

• ATP13A2 deficiency disrupts lysosomal polyamine export

  Sarah van Veen;Shaun Martin;Chris Van den Haute;Veronick Benoy

  247
  Citations

• HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

  Steve Stegen;Kjell Laperre;Guy Eelen;Gianmarco Rinaldi

  242
  Citations