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Patrick L.J.M. Zeeuwen

Patrick L.J.M. Zeeuwen

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
11915
World Ranking
16044
National Ranking
390

Overview

Patrick L.J.M. Zeeuwen is affiliated with Radboud University in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Dermatology and related subfields.

The main areas of study in their work include:

  • Dermatology and Skin Diseases
  • Allergic Rhinitis and Sensitization
  • Contact Dermatitis and Allergies
  • Advancements in Transdermal Drug Delivery
  • Transgenic Plants and Applications
  • Asthma and Respiratory Diseases
  • Nail Diseases and Treatments

The scientist has contributed extensively to research published in various venues. Frequent publication outlets include:

  • Journal of Investigative Dermatology
  • Experimental Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JID Innovations
  • The Journal of Dermatology

Among their recent papers are:

  • Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis (2021, JID Innovations)
  • Skin microbiota in health and disease: From sequencing to biology (2020, The Journal of Dermatology)
  • Vesicular hand eczema transcriptome analysis provides insights into its pathophysiology (2021, Experimental Dermatology)
  • Novel methodologies for host-microbe interactions and microbiome-targeted therapeutics in 3D organotypic skin models (2023, Microbiome)
  • Gram-positive anaerobic cocci guard skin homeostasis by regulating host-defense mechanisms (2023, iScience)

Frequent co-authors who collaborate with Zeeuwen include:

  • Ellen H. van den Bogaard
  • Joost Schalkwijk
  • Hanna Niehues
  • Diana Rodijk-Olthuis
  • Jos P.H. Smits

The subfields of study within the scientist's work consist of:

  • Dermatology
  • Immunology and Allergy
  • Molecular Biology
  • Immunology
  • Pharmaceutical Science

Best Publications

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Psoriasis is associated with increased beta-defensin genomic copy number.

    Edward J Hollox;Ulrike Huffmeier;Patrick L J M Zeeuwen;Raquel Palla

  • Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

    Rafael De Cid;Eva Riveira-Munoz;Patrick L.J.M. Zeeuwen;Jason Robarge

  • Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis

    Ellen H. van den Bogaard;Judith G.M. Bergboer;Mieke Vonk-Bergers;Ivonne M.J.J. van Vlijmen-Willems

  • Microbe-host interplay in atopic dermatitis and psoriasis

    Nanna Fyhrquist;Nanna Fyhrquist;Gareth Muirhead;Stefanie Prast-Nielsen;Marine Jeanmougin

  • High Expression Levels of Keratinocyte Antimicrobial Proteins in Psoriasis Compared with Atopic Dermatitis

    Gys J. de Jongh;Patrick L.J.M. Zeeuwen;Martina Kucharekova;Rolph Pfundt

  • Microbiome dynamics of human epidermis following skin barrier disruption

    Patrick L J M Zeeuwen;Jos Boekhorst;Ellen H van den Bogaard;Heleen D de Koning

  • Microbiome and skin diseases.

    Patrick L.J.M. Zeeuwen;Michiel Kleerebezem;Harro M. Timmerman;Joost Schalkwijk

  • SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking.

    H. O. F. Molhuizen;H. A. C. Alkemade;P. L. J. M. Zeeuwen;G. J. De Jongh

  • β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin

    Patrick A. M. Jansen;Diana Rodijk-Olthuis;Edward J. Hollox;Marijke Kamsteeg

  • Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats

    John A. L. Armour;Raquel Palla;Patrick L. J. M. Zeeuwen;Martin den Heijer

  • 3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function

    Hanna Niehues;Joke A. Bouwstra;Abdoel Waheb El Ghalbzouri;Johanna M. Brandner

  • Constitutive and Inducible Expression of SKALP/Elafin Provides Anti-Elastase Defense in Human Epithelia

    Rk Pfundt;F. Van Ruissen;I. M. J. J. Van Vlijmen-Willems;H. A. C. Alkemade

  • Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models.

    Jos P. H. Smits;Hanna Niehues;Gijs Rikken;Ivonne M. J. J. van Vlijmen-Willems

  • Epidermal differentiation: the role of proteases and their inhibitors.

    Patrick L.J.M. Zeeuwen

  • Induction of SLPI (ALP/HUSI-I) in Epidermal Keratinocytes

    M. Wingens;B.H. van Bergen;P.S. Hiemstra;J.F.G.M. Meis

  • Cystatin M/E expression is restricted to differentiated epidermal keratinocytes and sweat glands: a new skin-specific proteinase inhibitor that is a target for cross-linking by transglutaminase.

    P.L.J.M. Zeeuwen;I.M.J.J. van Vlijmen-Willems;B.J.H. Jansen;G. Sotiropoulou

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    L. C. Tsoi;S. L. Spain;J. Knight;E. Ellinghaus

Frequent Co-Authors

Joost Schalkwijk
Joost Schalkwijk Radboud University
Wiljan Hendriks
Wiljan Hendriks Radboud University Medical Center
Juha Kere
Juha Kere Karolinska Institute
Martin den Heijer
Martin den Heijer University of Amsterdam
John A.L. Armour
John A.L. Armour University of Nottingham
Jos Boekhorst
Jos Boekhorst Wageningen University & Research
James T. Elder
James T. Elder University of Michigan–Ann Arbor
André Reis
André Reis University of Erlangen-Nuremberg
Anna Simon
Anna Simon Christian Medical College & Hospital

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