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Darrel W. Stafford

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
15475
World Ranking
11816
National Ranking
5082

Darrel W. Stafford publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Darrel W. Stafford sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 182 publications — 42nd percentile

42% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Darrel W. Stafford D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Darrel W. Stafford sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 60 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Darrel W. Stafford is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple key fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, Medicine, and Nursing. These areas encompass a broad interdisciplinary approach to studying molecular mechanisms and clinical applications.

The scientist's work is concentrated in specific subfields such as Nutrition and Dietetics, Molecular Biology, Hematology, Cell Biology, and Genetics. These subfields represent the technical and thematic foundations underpinning their research output.

The main topics addressed by their research include:

  • Vitamin K Research Studies
  • Biotin and Related Studies
  • Hemophilia Treatment and Research
  • Hormonal Regulation and Hypertension
  • Enzyme function and inhibition
  • Platelet Disorders and Treatments
  • Pharmacogenetics and Drug Metabolism

Throughout their career, Darrel W. Stafford has contributed to academic literature published in several venues, with their most frequent publication platforms being:

  • UNC Libraries
  • Blood
  • Haemophilia
  • Journal of Thrombosis and Haemostasis
  • OPAL (Open@LaTrobe) (La Trobe University)

Selected recent publications illustrating their research include:

  • A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase, 2023, Nature Communications
  • γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K-dependent proteins, 2020, Blood
  • The Function of extravascular coagulation factor IX in haemostasis, 2021, Haemophilia
  • International consensus recommendations on the management of people with haemophilia B, 2022, Therapeutic Advances in Hematology
  • A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase, 2020, Journal of Thrombosis and Haemostasis

The scientist collaborates regularly with several frequent co-authors, reflecting a collaborative approach to their research field. These include:

  • Jian-Ke Tie
  • Da-Yun Jin
  • Xuejie Chen
  • David L. Straight
  • Da Yun Jin

Best Publications

  • A general method for isolation of high molecular weight DNA from eukaryotes

    Nikolaus Blin;Darrel W. Stafford

  • Identification of the gene for vitamin K epoxide reductase

    Tao Li;Chun Yun Chang;Da Yun Jin;Pen Jen Lin

  • Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

    Richard O. Snyder;Carol Miao;Leonard Meuse;Julie Tubb

  • The vitamin K cycle

    D. W. Stafford

  • A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B

    Hui Feng Lin;Nobuyo Maeda;Oliver Smithies;David L. Straight

  • Cloning and expression of the cDNA for human γ-glutamyl carboxylase

    Sheue Mei Wu;Wing Fai Cheung;Dan Frazier;Darrel W. Stafford

  • Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family.

    Neil F. Rebbe;Jerry Ware;Rogier M. Bertina;Paul Modrich

  • Nucleotide Sequence and Deduced Primary Structure of Cellobiohydrolase II from Trichoderma Reesei

    Chung Mong Chen;Mikelina Gritzali;Darrel W. Stafford

  • A Missense Mutation in γ-Glutamyl Carboxylase Gene Causes Combined Deficiency of All Vitamin K-Dependent Blood Coagulation Factors

    Benjamin Brenner;Beatriz Sánchez-Vega;Beatriz Sánchez-Vega;Sheue Mei Wu;Sheue Mei Wu;Naomi Lanir;Naomi Lanir

  • Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry.

    Christine M. Hebling;Christopher R. Morgan;Darrel W. Stafford;James W. Jorgenson

  • Human Factor IX Corrects the Bleeding Diathesis of Mice With Hemophilia B

    Szu Hao Kung;J. N. Hagstrom;Darrell Cass;Shing Jen Tai

  • The Propeptides of the Vitamin K-dependent Proteins Possess Different Affinities for the Vitamin K-dependent Carboxylase

    Thomas B. Stanley;Da Yun Jin;Pen Jen Lin;Darrel W Stafford

  • Membrane Topology Mapping of Vitamin K Epoxide Reductase by in Vitro Translation/Cotranslocation

    Jian-Ke Tie;Christopher V. Nicchitta;Gunnar von Heijne;Darrel W. Stafford

  • Employing a Gain-of-Function Factor IX Variant R338L to Advance the Efficacy and Safety of Hemophilia B Human Gene Therapy: Preclinical Evaluation Supporting an Ongoing Adeno-Associated Virus Clinical Trial

    Paul E Monahan;Junjiang Sun;Tong Gui;Genlin Hu

  • Enhanced gamma-carboxylation of recombinant factor X using a chimeric construct containing the prothrombin propeptide.

    Rodney M. Camire;Peter J. Larson;Darrel W. Stafford;Katherine A. High

  • Changing Residue 338 in Human Factor IX from Arginine to Alanine Causes an Increase in Catalytic Activity

    Jinli Chang;Jianping Jin;Pete Lollar;Wolfram Bode

  • A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism.

    Kirk Chu;Sheue Mei Wu;Tom Stanley;Darrel W. Stafford

  • Processive Post-translational Modification VITAMIN K-DEPENDENT CARBOXYLATION OF A PEPTIDE SUBSTRATE

    Daniel P. Morris;Robert D. Stevens;David J. Wright;Darrel W. Stafford

  • Evidence for a prevalent dimorphism in the activation peptide of human coagulation factor IX.

    R A McGraw;L M Davis;C M Noyes;R L Lundblad

  • Identification and purification to near homogeneity of the vitamin K-dependent carboxylase.

    Sheue Mei Wu;Daniel P. Morris;Darrel W. Stafford

Frequent Co-Authors

Lee G. Pedersen
Lee G. Pedersen University of North Carolina at Chapel Hill
Katherine A. High
Katherine A. High Children's Hospital of Philadelphia
Cees Vermeer
Cees Vermeer Maastricht University
Jerry Ware
Jerry Ware University of Arkansas for Medical Sciences
Dougald M. Monroe
Dougald M. Monroe University of North Carolina at Chapel Hill
Heyu Ni
Heyu Ni University of Toronto
James W. Jorgenson
James W. Jorgenson University of North Carolina at Chapel Hill
Lalith Perera
Lalith Perera National Institutes of Health
John R. Engen
John R. Engen Northeastern University
Yoshihide Kanaoka
Yoshihide Kanaoka Brigham and Women's Hospital

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Best Scientists Citing Darrel W. Stafford

Katherine A. High

Katherine A. High

Children's Hospital of Philadelphia

Publications: 102

Valder R. Arruda

Valder R. Arruda

University of Pennsylvania

Publications: 50

Roland W. Herzog

Roland W. Herzog

Indiana University

Publications: 46

Johannes Oldenburg

Johannes Oldenburg

University of Bonn

Publications: 44

Norihiro Okada

Norihiro Okada

National Cheng Kung University

Publications: 41

Mark A. Kay

Mark A. Kay

Stanford University

Publications: 27

James M. Wilson

James M. Wilson

University of Pennsylvania

Publications: 26

Leon J. Schurgers

Leon J. Schurgers

Maastricht University

Publications: 26

Dougald M. Monroe

Dougald M. Monroe

University of North Carolina at Chapel Hill

Publications: 26

Clemens R. Müller

Clemens R. Müller

University of Würzburg

Publications: 26

Bruce Furie

Bruce Furie

Beth Israel Deaconess Medical Center

Publications: 25

Johan Stenflo

Johan Stenflo

Lund University

Publications: 23

Manfred Schartl

Manfred Schartl

University of Würzburg

Publications: 22

Sriram Krishnaswamy

Sriram Krishnaswamy

Children's Hospital of Philadelphia

Publications: 21

Cees Vermeer

Cees Vermeer

Maastricht University

Publications: 21

David Lillicrap

David Lillicrap

Queen's University

Publications: 20

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