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Biology and Biochemistry

D-Index
49
Citations
13562
World Ranking
17860
National Ranking
7309

Overview

Jeremy C. Allegood is affiliated with Virginia Commonwealth University in the United States. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, they have contributed extensively to Molecular Biology, Cell Biology, Epidemiology, Immunology, and Clinical Biochemistry.

The scientist's work mainly focuses on several key topics related to lipid biology and disease mechanisms:

  • Sphingolipid Metabolism and Signaling
  • Liver Disease Diagnosis and Treatment
  • Endoplasmic Reticulum Stress and Disease
  • Metabolism and Genetic Disorders
  • Lipid Membrane Structure and Behavior
  • Mitochondrial Function and Pathology
  • Immune cells in cancer

Jeremy C. Allegood has published in a variety of scientific venues, with multiple papers appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Lipid Research
  • Circulation
  • Journal of Visualized Experiments
  • eLife

Some of their recent publications include:

  • "Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex," 2020, eLife
  • "Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination," 2020, Journal of Lipid Research
  • "Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction," 2020, Journal of the American College of Cardiology
  • "Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury," 2021, Molecular Neurobiology
  • "Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH," 2022, Molecular Metabolism

The scientist frequently collaborates with other researchers. Their most common co-authors include:

  • L. Ashley Cowart
  • David Montefusco
  • Yue Yang
  • Maryam Jamil
  • Moshe Levi

Best Publications

  • Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

    Nitai C. Hait;Jeremy Allegood;Michael Maceyka;Graham M. Strub

  • Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

    Sergio E. Alvarez;Kuzhuvelil B. Harikumar;Nitai C. Hait;Jeremy Allegood

  • Fumonisins Disrupt Sphingolipid Metabolism, Folate Transport, and Neural Tube Development in Embryo Culture and In Vivo: A Potential Risk Factor for Human Neural Tube Defects among Populations Consuming Fumonisin-Contaminated Maize

    Walter F O Marasas;Ronald T. Riley;Katherine A. Hendricks;Victoria L. Stevens

  • Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry.

    Alfred H. Merrill;M. Cameron Sullards;Jeremy C. Allegood;Samuel Kelly

  • Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

    Wenjing Zheng;Jessica Kollmeyer;Holly Symolon;Amin Momin

  • Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

    Jie Liang;Masayuki Nagahashi;Eugene Y. Kim;Kuzhuvelil B. Harikumar

  • Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

    Rebecca L. Shaner;Jeremy C. Allegood;Hyejung Park;Elaine Wang

  • Two Mammalian Longevity Assurance Gene (LAG1) Family Members, trh1 and trh4, Regulate Dihydroceramide Synthesis Using Different Fatty Acyl-CoA Donors

    Christian Riebeling;Jeremy C. Allegood;Elaine Wang;Alfred H. Merrill

  • Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells.

    Krishnan Venkataraman;Christian Riebeling;Jacques Bodennec;Howard Riezman

  • Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

    Graham M. Strub;Melanie Paillard;Jie Liang;Ludovic Gomez

  • Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.

    Masayuki Nagahashi;Subramaniam Ramachandran;Eugene Y. Kim;Jeremy C. Allegood

  • Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

    Kazuaki Takabe;Roger H. Kim;Jeremy C. Allegood;Poulami Mitra

  • Mutation of β-glucosidase 2 causes glycolipid storage disease and impaired male fertility

    Yildiz Yildiz;Heidrun Matern;Bonne Thompson;Jeremy C. Allegood

  • Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans

    Philipp C. Rittershaus;Talar B. Kechichian;Jeremy C. Allegood;Alfred H. Merrill

  • Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis

    Kena Desai;M.Cameron Sullards;Jeremy Allegood;Elaine Wang

  • Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

    Nitai C Hait;Laura E Wise;Jeremy C Allegood;Megan O'Brien

  • TARGETING SPHINGOSINE KINASE 1 INHIBITS AKT SIGNALING, INDUCES APOPTOSIS, AND SUPPRESSES GROWTH OF HUMAN GLIOBLASTOMA CELLS AND XENOGRAFTS

    Dmitri Kapitonov;Jeremy C. Allegood;Clint Mitchell;Nitai C. Hait

  • Imaging MALDI mass spectrometry using an oscillating capillary nebulizer matrix coating system and its application to analysis of lipids in brain from a mouse model of Tay-Sachs/Sandhoff disease.

    Yanfeng Chen;Jeremy Allegood;Ying Liu;Elaine Wang

  • Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

    Masayuki Nagahashi;Akimitsu Yamada;Akimitsu Yamada;Eriko Katsuta;Eriko Katsuta;Tomoyoshi Aoyagi

  • Ceramide transfer protein function is essential for normal oxidative stress response and lifespan

    Raghavendra Pralhada Rao;Changqing Yuan;Jeremy C. Allegood;Satinder S. Rawat

Frequent Co-Authors

Sarah Spiegel
Sarah Spiegel Virginia Commonwealth University
Sheldon Milstien
Sheldon Milstien Virginia Commonwealth University
Alfred H. Merrill
Alfred H. Merrill Georgia Institute of Technology
Kazuaki Takabe
Kazuaki Takabe Roswell Park Cancer Institute
Elaine Wang
Elaine Wang Georgia Institute of Technology
Paul Dent
Paul Dent Virginia Commonwealth University
Steven Grant
Steven Grant Virginia Commonwealth University
Edward J. Lesnefsky
Edward J. Lesnefsky Virginia Commonwealth University
Charles E. Chalfant
Charles E. Chalfant Virginia Commonwealth University
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University

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