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Microbiology

D-Index
65
Citations
15500
World Ranking
2500
National Ranking
88

Overview

Paul R. Young is affiliated with the University of Queensland in Australia and primarily works in the field of Medicine. Their research covers several subfields including Infectious Diseases, Epidemiology, Public Health, Environmental and Occupational Health, Surgery, and Immunology. The main topics addressed by their work include SARS-CoV-2 and COVID-19 Research, Viral Infections and Vectors, Mosquito-borne diseases and control, Respiratory viral infections research, Animal Virus Infections Studies, COVID-19 Clinical Research Studies, and Immunotherapy and Immune Responses.

Their recent scholarly contributions include:

  • Systems serology detects functionally distinct coronavirus antibody features in children and elderly, 2021, Nature Communications
  • A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses, 2021, Nature Communications
  • SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein, 2022, Molecular Psychiatry
  • Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial, 2021, The Lancet Infectious Diseases
  • A broadly protective antibody that targets the flavivirus NS1 protein, 2021, Science

Frequent co-authors collaborating with Paul R. Young include:

  • Daniel Watterson
  • Naphak Modhiran
  • Keith J. Chappell
  • Alberto A. Amarilla
  • Christopher L. D. McMillan

Publications by Paul R. Young have appeared commonly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Vaccines
  • Nature Communications
  • Frontiers in Immunology
  • npj Vaccines

Best Publications

  • High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

    Daniel H. Libraty;Paul R. Young;Darren Pickering;Timothy P. Endy

  • An Antigen Capture Enzyme-Linked Immunosorbent Assay Reveals High Levels of the Dengue Virus Protein NS1 in the Sera of Infected Patients

    Paul R. Young;Paul R. Young;Paige A. Hilditch;Cheryl Bletchly;Wendy Halloran

  • The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

    Martina Beltramello;Katherine L. Williams;Cameron P. Simmons;Annalisa Macagno

  • The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker.

    David A. Muller;Paul R. Young

  • Immunolocalization of the Dengue Virus Nonstructural Glycoprotein NS1 Suggests a Role in Viral RNA Replication

    Jason M. Mackenzie;Malcolm K. Jones;Paul R. Young;Paul R. Young

  • Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

    Naphak Modhiran;Daniel Watterson;David A. Muller;Adele K. Panetta

  • Clinical and Laboratory Diagnosis of Dengue Virus Infection.

    David A. Muller;Alexandra C. I. Depelsenaire;Paul R. Young

  • Retroviral invasion of the koala genome

    Rachael E. Tarlinton;Joanne Meers;Paul R. Young

  • Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors

    Donmienne Leung;Kate Schroder;Helen White;Ning-Xia Fang

  • Maternal antibody and viral factors in the pathogenesis of dengue virus in infants.

    Cameron P. Simmons;Tran Nguyen Bich Chau;Tran Thi Thuy;Nguyen Minh Tuan

  • The Diagnostic Sensitivity of Dengue Rapid Test Assays Is Significantly Enhanced by Using a Combined Antigen and Antibody Testing Approach

    Scott R. Fry;Michelle Meyer;Matthew G. Semple;Cameron P. Simmons

  • Kinetics of Plasma Viremia and Soluble Nonstructural Protein 1 Concentrations in Dengue: Differential Effects According to Serotype and Immune Status

    Huynh Thi Le Duyen;Tran Van Ngoc;Do T. Ha;Vu Thi Ty Hang

  • Wolbachia-mediated resistance to dengue virus infection and death at the cellular level.

    Francesca D. Frentiu;Jodie Robinson;Paul R. Young;Elizabeth A. McGraw

  • Dengue virus nonstructural protein 1 is expressed in a glycosyl-phosphatidylinositol-linked form that is capable of signal transduction

    Michael G. Jacobs;Peter J. Robinson;Cheryl Bletchly;Jason M. Mackenzie

  • Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

    Rosemary S. Harrison;Nicholas E. Shepherd;Huy N. Hoang;Gloria Ruiz-Gómez

  • The Role of Histidine Residues in Low-pH-Mediated Viral Membrane Fusion

    Thorsten Kampmann;Daniela S. Mueller;Daniela S. Mueller;Alan E. Mark;Alan E. Mark;Paul R. Young

  • Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas.

    Rachael Tarlinton;Joanne Meers;Jon Hanger;Paul Young

  • Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

    Gautier Robin;Keith Chappell;Martin J. Stoermer;Shu-Hong Hu

  • Prevalence of Koala Retrovirus in Geographically Diverse Populations in Australia

    GS Simmons;PR Young;JJ Hanger;K Jones

  • Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein.

    F. Megret;J.P. Hugnot;A. Falconar;M.K. Gentry

  • Systems serology detects functionally distinct coronavirus antibody features in children and elderly.

    Kevin J. Selva;Carolien E. van de Sandt;Carolien E. van de Sandt;Melissa M. Lemke;Christina Y. Lee

  • Stable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors.

    Andrei N. Varnavski;Paul R. Young;Paul R. Young;Alexander A. Khromykh

Frequent Co-Authors

David P. Fairlie
David P. Fairlie University of Queensland
Bostjan Kobe
Bostjan Kobe University of Queensland
Roy A. Hall
Roy A. Hall University of Queensland
Alexander A. Khromykh
Alexander A. Khromykh University of Queensland
Peter D. Sly
Peter D. Sly University of Queensland
Andreas Suhrbier
Andreas Suhrbier QIMR Berghofer Medical Research Institute
P. Mark Hogarth
P. Mark Hogarth Burnet Institute
Jason M. Mackenzie
Jason M. Mackenzie University of Melbourne
Jennifer L. Martin
Jennifer L. Martin University of Wollongong
Alan E. Mark
Alan E. Mark University of Queensland

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