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Jason M. Mackenzie

Jason M. Mackenzie

D-Index & Metrics

Microbiology

D-Index
51
Citations
10645
World Ranking
4303
National Ranking
133

Overview

Jason M. Mackenzie is affiliated with the University of Melbourne in Australia. Their research primarily focuses on medicine, with particular attention to infectious diseases, public health, environmental and occupational health, immunology, epidemiology, and genetics.

The scientist's research encompasses several main topics including viral gastroenteritis research and epidemiology, SARS-CoV-2 and COVID-19 research, mosquito-borne diseases and control, virus-based gene therapy research, interferon and immune responses, influenza virus research studies, and insect symbiosis with bacterial influences.

Mackenzie's recent publications include:

  • A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses, 2021, Nature Communications
  • SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon, 2021, PLoS Pathogens
  • Lipid droplets and lipid mediators in viral infection and immunity, 2020, FEMS Microbiology Reviews
  • Modulation of acyl-carnitines, the broad mechanism behind Wolbachia-mediated inhibition of medically important flaviviruses in Aedes aegypti, 2020, Proceedings of the National Academy of Sciences
  • Monocyte apoptotic bodies are vehicles for influenza A virus propagation, 2020, Communications Biology

Frequent co-authors of Jason M. Mackenzie include:

  • Joshua M. Deerain
  • Julio Carrera Montoya
  • Damian F. J. Purcell
  • Julie McAuley
  • Turgut E. Aktepe

The scientist has published regularly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Virology
  • PLoS Pathogens
  • mBio
  • mSphere

Best Publications

  • Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages

    Christiane E. Wobus;Stephanie M. Karst;Larissa B. Thackray;Kyeong Ok Chang

  • Immunolocalization of the Dengue Virus Nonstructural Glycoprotein NS1 Suggests a Role in Viral RNA Replication

    Jason M. Mackenzie;Malcolm K. Jones;Paul R. Young;Paul R. Young

  • Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures.

    Edwin G. Westaway;Jason M. MacKenzie;Mark T. Kenney;Malcolm K. Jones

  • Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A

    Jason M. Mackenzie;Alexander A. Khromykh;Malcolm K. Jones;Edwin G. Westaway

  • The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex.

    Leah K. Gillespie;Antje Hoenen;Gary Morgan;Jason M. Mackenzie

  • Assembly and Maturation of the Flavivirus Kunjin Virus Appear To Occur in the Rough Endoplasmic Reticulum and along the Secretory Pathway, Respectively

    Jason M. Mackenzie;Edwin G. Westaway

  • Cholesterol manipulation by West Nile virus perturbs the cellular immune response.

    Jason M. Mackenzie;Alexander A. Khromykh;Robert G. Parton

  • Wrapping Things up about Virus RNA Replication

    Jason Mackenzie

  • Crystal Structure of the RNA Polymerase Domain of the West Nile Virus Non-structural Protein 5

    Helene Malet;Marie-Pierre Egloff;Barbara Selisko;Rebecca Elizabeth Butcher

  • Role of Nonstructural Protein NS2A in Flavivirus Assembly

    Jason Y. Leung;Gorben P. Pijlman;Gorben P. Pijlman;Natasha Kondratieva;Jennifer Hyde

  • Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein

    Jojanneke Roosendaal;Edwin G. Westaway;Alexander Khromykh;Alexander Khromykh;Jason M. Mackenzie;Jason M. Mackenzie

  • Markers for trans-Golgi Membranes and the Intermediate Compartment Localize to Induced Membranes with Distinct Replication Functions in Flavivirus-Infected Cells

    Jason M. Mackenzie;Malcolm K. Jones;Edwin G. Westaway

  • Circulating microRNAs involved in multiple sclerosis

    Sue Rutherford Siegel;Jason Mackenzie;George Chaplin;Nina G. Jablonski

  • West Nile virus differentially modulates the unfolded protein response to facilitate replication and immune evasion.

    Rebecca L. Ambrose;Jason M. Mackenzie

  • West Nile Virus Core Protein: Tetramer Structure and Ribbon Formation

    Terje Dokland;Terje Dokland;Martin Walsh;Jason M. Mackenzie;Alexander A. Khromykh

  • The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles.

    Scott R. Schaecher;Jason M. Mackenzie;Andrew Pekosz

  • Dengue virus nonstructural protein 1 is expressed in a glycosyl-phosphatidylinositol-linked form that is capable of signal transduction

    Michael G. Jacobs;Peter J. Robinson;Cheryl Bletchly;Jason M. Mackenzie

  • Proteins C and NS4B of the Flavivirus Kunjin Translocate Independently into the Nucleus

    Edwin G. Westaway;Alexander A. Khromykh;Mark T. Kenney;Jason M. Mackenzie

  • A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses.

    Alberto A. Amarilla;Julian D. J. Sng;Rhys Parry;Joshua M. Deerain

  • Mouse Norovirus Replication Is Associated with Virus-Induced Vesicle Clusters Originating from Membranes Derived from the Secretory Pathway

    Jennifer L. Hyde;Stanislav V. Sosnovtsev;Kim Y. Green;Christiane Wobus

  • Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexes.

    Edwin G. Westaway;Alexander A. Khromykh;Jason M. Mackenzie

Frequent Co-Authors

Alexander A. Khromykh
Alexander A. Khromykh University of Queensland
Peter A. White
Peter A. White University of New South Wales
Paul R. Young
Paul R. Young University of Queensland
Eric J. Gowans
Eric J. Gowans University of Adelaide
Cameron P. Simmons
Cameron P. Simmons University College London
Lyn R. Griffiths
Lyn R. Griffiths Queensland University of Technology
Malcolm K. Jones
Malcolm K. Jones University of Queensland
Michael P. Pender
Michael P. Pender University of Queensland
Robert G. Parton
Robert G. Parton University of Queensland
Gorben P. Pijlman
Gorben P. Pijlman Wageningen University & Research

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