World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
18849
World Ranking
12939
National Ranking
5511

Overview

Michael Eckhaus is a researcher primarily affiliated with the National Institutes of Health in the United States. Their scientific work spans several interconnected fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. The subfields they concentrate on include Immunology, Molecular Biology, Genetics, Hematology, and Oncology.

The scientist's research explores various topics with notable focus on:

  • Immune Cell Function and Interaction
  • CAR-T Cell Therapy Research
  • Virus-based Gene Therapy Research
  • Immune Cells in Cancer
  • Hematopoietic Stem Cell Transplantation
  • Nuclear Structure and Function
  • RNA Research and Splicing

Michael Eckhaus has contributed to numerous publications across several established venues, with a frequent presence in Frontiers in Immunology, Blood, and Biology of Blood and Marrow Transplantation. Other publication venues include Nature Medicine and the Journal of Clinical Investigation.

The following recent papers highlight aspects of their involvement or contribution in the biomedical sciences:

  • "A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome," 2021, Nature Medicine
  • "Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients," 2020, Journal of Clinical Investigation
  • "TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis," 2023, Science Signaling
  • "Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson-Gilford Progeria syndrome," 2021, Aging Cell
  • "Transcatheter Myotomy to Relieve Left Ventricular Outflow Tract Obstruction: The Septal Scoring Along the Midline Endocardium Procedure in Animals," 2022, Circulation Cardiovascular Interventions

Frequent collaborators include Rochelle Fletcher, Natália Schneider, Christopher G. Kanakry, Shanzay M. Khan, and David Venzon.

Best Publications

  • Atm-deficient mice: a paradigm of ataxia telangiectasia.

    Carrolee Barlow;Shinji Hirotsune;Richard Paylor;Marek Liyanage

  • Genomic instability in mice lacking histone H2AX.

    Arkady Celeste;Simone Petersen;Peter J. Romanienko;Oscar Fernandez-Capetillo

  • Life without white fat: a transgenic mouse

    Jaideep Moitra;Mark M. Mason;Michelle Olive;Dmitry Krylov

  • Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

    Oksana Gavrilova;Bernice Marcus-Samuels;David Graham;Jason K. Kim

  • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

    Rui Hong Wang;Cuiling Li;Xiaoling Xu;Yin Zheng

  • H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility

    Arkady Celeste;Simone Difilippantonio;Michael J. Difilippantonio;Oscar Fernandez-Capetillo

  • Variable and tissue-specific hormone resistance in heterotrimeric Gs protein α-subunit (Gsα) knockout mice is due to tissue-specific imprinting of the Gsα gene

    Shuhua Yu;Dawen Yu;Eric Lee;Michael Eckhaus

  • Retro-orbital injections in mice.

    Tal Yardeni;Michael Eckhaus;H. Douglas Morris;Marjan Huizing

  • Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

    Muhammad M. Mohiuddin;Avneesh K. Singh;Philip C. Corcoran;Marvin L. Thomas

  • Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

    Ryuya Yamanaka;Carrolee Barlow;Julie Lekstrom-Himes;Lucio H. Castilla

  • HIV-associated nephropathy in transgenic mice expressing HIV-1 genes.

    Peter Dickie;James Felser;Michael Eckhaus;Joseph Bryant

  • Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

    Masashi Shingai;Olivia K. Donau;Ronald J. Plishka;Alicia Buckler-White

  • Failure of Embryonic Hematopoiesis andLethal Hemorrhages in Mouse Embryos Heterozygousfor a Knocked-In Leukemia Gene CBFB–MYH11

    Lucio H Castilla;Cisca Wijmenga;Qing Wang;Terryl Stacy

  • The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia.

    Lucio H. Castilla;Lisa Garrett;Neeraj Adya;Donald Orlic

  • Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes.

    Jeffrey B. Kopp;Mary E. Klotman;Scott H. Adler;Leslie A. Bruggeman

  • Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

    Pamela M. Pollock;Karine Cohen-Solal;Raman Sood;Jin Namkoong

  • Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution

    Gennadiy Kovtunovych;Michael A. Eckhaus;Manik C. Ghosh;Hayden Ollivierre-Wilson

  • Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

    Simone Difilippantonio;Arkady Celeste;Oscar Fernandez-Capetillo;Hua-Tang Chen

  • Cbfbeta interacts with Runx2 and has a critical role in bone development.

    Mondira Kundu;Amjad Javed;Jae-Pil Jeon;Alan Horner

  • Posttransplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression

    Lucas P. Wachsmuth;Michael T. Patterson;Michael A. Eckhaus;David J. Venzon

Frequent Co-Authors

Ronald E. Gress
Ronald E. Gress National Institutes of Health
David Ayares
David Ayares University of Maryland, Baltimore
Anthony Wynshaw-Boris
Anthony Wynshaw-Boris Case Western Reserve University
Arian Laurence
Arian Laurence University of Oxford
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Tracey A. Rouault
Tracey A. Rouault National Institutes of Health
Thomas Ried
Thomas Ried National Institutes of Health
Keith A. Reimann
Keith A. Reimann Harvard Medical School
Yun C. Chang
Yun C. Chang National Institutes of Health
Kyung J. Kwon-Chung
Kyung J. Kwon-Chung National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can lead to diverse career options, especially when complemented by related online degrees. For those interested in healthcare, online nursing programs provide a flexible pathway to becoming a registered nurse and working on the frontlines of patient care.

Nutrition is a vital branch of biological sciences. Earning an online dietitian degree equips you with the expert knowledge to guide patients on healthy eating and specialized diets, expanding opportunities in healthcare and wellness sectors.

For those aiming for leadership roles in healthcare organizations, enrolling in top cahme accredited mha programs can develop your management, policy, and decision-making skills, opening doors in hospital settings, public health institutions, and beyond.

Ambitious professionals interested in the highest clinical qualifications can consider online dnp programs without dissertation. These programs help you achieve advanced practice credentials with a flexible, research-friendly structure.

Combining Biology or Biochemistry knowledge with these online degrees can enhance your expertise, broaden your career prospects, and provide flexibility in how you learn and progress in related fields.

Best Scientists Citing Michael Eckhaus

Trending Scientists

Recently Published Articles