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Genetics

D-Index
56
Citations
11286
World Ranking
3506
National Ranking
420

Overview

Veronica J. Buckle is affiliated with the University of Oxford in the United Kingdom. Their research is primarily situated within the fields of Biochemistry, Genetics, and Molecular Biology, with a focus on molecular biology, genetics, plant science, biophysics, and physiology.

The scientist's work covers several main topics, including:

  • Genomics and Chromatin Dynamics
  • Chromosomal and Genetic Variations
  • Single-cell and Spatial Transcriptomics
  • RNA Research and Splicing
  • Genomic Variations and Chromosomal Abnormalities
  • RNA and Protein Synthesis Mechanisms
  • Genomics and Phylogenetic Studies

Veronica J. Buckle has published extensively in high-profile journals. Frequent publication venues include:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Journal of Medical Genetics
  • Science Advances

Selected recent papers illustrate the scope of their work:

  • "Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin," 2020, Science Advances
  • "Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells," 2020, Cell Reports
  • "Dynamics of the 4D genome during in vivo lineage specification and differentiation," 2020, Nature Communications
  • "A Dynamic Folded Hairpin Conformation Is Associated with α-Globin Activation in Erythroid Cells," 2020, Cell Reports
  • "High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale," 2021, Nature Communications

The scientist collaborates regularly with other researchers. Frequent co-authors include:

  • Jill M. Brown
  • Douglas R. Higgs
  • Jim R. Hughes
  • Christian Babbs
  • Sara De Ornellas

The research output reflects a multi-disciplinary approach, combining aspects of molecular biology and genetics with computational and biophysical methods to investigate genome structure and function. The work spans chromatin dynamics, gene regulation, and genome organization in various biological contexts.

Best Publications

  • The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation.

    Jonathan Flint;Andrew O.M. Wilkie;Veronica J. Buckle;Robin M. Winter

  • Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia

    Dengli Hong;Rajeev Gupta;Philip Ancliff;Ann Atzberger

  • Structure and polymorphism of human telomere-associated DNA

    William R.A. Brown;Philip J. MacKinnon;Alfredo Villasanté;Nigel Spurr

  • Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Jenny C. Taylor;Jenny C. Taylor;Hilary C. Martin;Stefano Lise;John Broxholme

  • A Regulatory SNP Causes a Human Genetic Disease by Creating a New Transcriptional Promoter

    Marco De Gobbi;Vip Viprakasit;Jim R Hughes;Chris Fisher

  • Intragenic Enhancers Act as Alternative Promoters

    Monika S. Kowalczyk;Jim R. Hughes;David Garrick;Magnus D. Lynch

  • Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

    Jill M. Brown;Joanne Green;Ricardo Pires das Neves;Helen A.C. Wallace

  • LOCALIZATION OF A PUTATIVE TRANSCRIPTIONAL REGULATOR (ATRX) AT PERICENTROMERIC HETEROCHROMATIN AND THE SHORT ARMS OF ACROCENTRIC CHROMOSOMES

    T. L. McDowell;R. J. Gibbons;H. Sutherland;D. M. O’Rourke

  • Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome.

    J. Wolfe;S.M. Darling;R.P. Erickson;I.W. Craig

  • α-particle-induced chromosomal instability in human bone marrow cells

    M.A. Kadhim;S.A. Lorimore;D.T. Goodhead;E.G. Wright

  • Coregulated human globin genes are frequently in spatial proximity when active

    Jill M. Brown;Joanne Leach;Joyce E. Reittie;Ann Atzberger

  • Chromosome maps of man and mouse. IV.

    A. G. Searle;J. Peters;M. F. Lyon;J. G. Hall;J. G. Hall

  • Radiation-induced genomic instability: delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells.

    M.A. Kadhim;S.A. Lorimore;K.M.S. Townsend;D.T. Goodhead

  • Chromosome maps of man and mouse, III.

    A.G. Searle;J. Peters;M.F. Lyon;E.P. Evans

  • Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16.

    Andrew O.M. Wilkie;Douglas R. Higgs;Katrina A. Rack;Veronica J. Buckle

  • Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.

    Karen E. Brown;Shannon Amoils;Jacqueline M. Horn;Veronica J. Buckle

  • A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype

    Lynn Pritchard;Jackie A. Sloane-Stanley;Jackie A. Sharpe;Richard Aspinwall

  • Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

    A. Marieke Oudelaar;James O. J. Davies;Lars L. P. Hanssen;Jelena M. Telenius

  • Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

    Johannes Schödel;Chiara Bardella;Lina K Sciesielski;Jill M. Brown

  • Telomere directed fragmentation of mammalian chromosomes

    Michael A. Barnett;Veronica J. Buckle;Edward P. Evans;Andrew C.G. Porter

Frequent Co-Authors

Douglas R. Higgs
Douglas R. Higgs University of Oxford
James Hughes
James Hughes Emory University
William G. Wood
William G. Wood University of Oxford
Andrew O.M. Wilkie
Andrew O.M. Wilkie University of Oxford
David Oscier
David Oscier Royal Bournemouth Hospital
Richard J. Gibbons
Richard J. Gibbons University of Oxford
Simon J. McGowan
Simon J. McGowan University of Oxford
Afaf H. El-Sagheer
Afaf H. El-Sagheer University of Southampton
Ian W. Craig
Ian W. Craig King's College London
Peter C. Harris
Peter C. Harris Mayo Clinic

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