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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
12970
World Ranking
16007
National Ranking
1262

Overview

David Edgar is affiliated with the University of Liverpool in the United Kingdom. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with specific focus on areas including Immunology, Genetics, Surgery, Infectious Diseases, and Pulmonary and Respiratory Medicine.

The scientist has published extensively on topics related to Immunodeficiency and Autoimmune Disorders, Parvovirus B19 Infection Studies, Blood disorders and treatments, Cystic Fibrosis Research Advances, Congenital gastrointestinal and neural anomalies, Cell Adhesion Molecules Research, and DNA Repair Mechanisms.

Frequent coauthors collaborating with David Edgar include Matthew Buckland, Gerhard Kindle, Niall Conlon, Mikko Seppänen, and Lisa Devlin.

The venues where their work has appeared most often include the Journal of Clinical Immunology, Clinical & Experimental Immunology, bioRxiv (Cold Spring Harbor Laboratory), Journal of Allergy and Clinical Immunology, and European Journal Of Haematology.

Recent papers authored or co-authored by David Edgar include:

  • Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations (2021, Journal of Allergy and Clinical Immunology)
  • Treating secondary antibody deficiency in patients with haematological malignancy: European expert consensus (2021, European Journal Of Haematology)
  • GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements (2022, Nature Communications)
  • Autosomal Dominant STAT6 Gain of Function Causes Severe Atopy Associated with Lymphoma (2023, Journal of Clinical Immunology)
  • Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia (2021, Journal of Clinical Immunology)

Best Publications

  • Purification of a new neurotrophic factor from mammalian brain.

    Y.A. Barde;D. Edgar;H. Thoenen

  • A simplified laminin nomenclature

    Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann

  • The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

    D Edgar;R Timpl;H Thoenen

  • Absence of Basement Membranes after Targeting the LAMC1 Gene Results in Embryonic Lethality Due to Failure of Endoderm Differentiation

    Neil Smyth;H. Seda Vatansever;Patricia Murray;Michael Meyer

  • Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation

    Shaohua Li;David Harrison;Salvatore Carbonetto;Salvatore Carbonetto;Reinhard Fässler

  • Sensory neurons in culture: Changing requirements for survival factors during embryonic development

    Y.-A. Barde;D. Edgar;H. Thoenen

  • The role of laminin in embryonic cell polarization and tissue organization.

    Shaohua Li;David Edgar;Reinhard Fässler;William Wadsworth

  • The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.

    M Aumailley;V Nurcombe;D Edgar;M Paulsson

  • NEW NEUROTROPHIC FACTORS

    Y A Barde;D Edgar;H Thoenen

  • Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain.

    Rainer Deutzmann;Monique Aumailley;Hanna Wiedemann;Werner Pysny

  • Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies.

    David Edgar;Rupert Timpl;Hans Thoenen

  • Characterisation and transplantation of enteric nervous system progenitor cells

    Sarah Almond;Richard M Lindley;Simon E Kenny;M Gwen Connell

  • Regulation of Programmed Cell Death by Basement Membranes in Embryonic Development

    Patricia Murray;David Edgar

  • Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture.

    Ulrike Dohrmann;David Edgar;Michael Sendtner;Hans Thoenen

  • Subpopulations of cultured chick sympathetic neurones differ in their requirements for survival factors

    David Edgar;Yves-Alain Barde;Hans Thoenen

  • The regulation of embryonic stem cell differentiation by leukaemia inhibitory factor (LIF)

    Patricia Murray;David Edgar

  • Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon.

    Richard M. Lindley;Daniel B. Hawcutt;M. Gwen Connell;Sarah N. Almond

  • The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGF.

    U. Ernsberger;D. Edgar;H. Rohrer

  • Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum

    M A Leibl;T Ota;M N Woodward;S E Kenny

  • Characterisation and transplantation of enteric nervous system progenitor cells. Commentary

    Michael D. Gershon;Sarah Almond;Richard M. Lindley;Simon E. Kenny

Frequent Co-Authors

Hans Thoenen
Hans Thoenen Max Planck Society
Yves-Alain Barde
Yves-Alain Barde Cardiff University
Ronald M. Lindsay
Ronald M. Lindsay Zebra Biologics (United States)
Friedrich Lottspeich
Friedrich Lottspeich Max Planck Society
George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
Rupert Timpl
Rupert Timpl Max Planck Society
Hermann Rohrer
Hermann Rohrer Goethe University Frankfurt
Neil Smyth
Neil Smyth University of Southampton
Peter D. Yurchenco
Peter D. Yurchenco Rutgers, The State University of New Jersey
Robert D. Short
Robert D. Short Lancaster University

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