The scientist’s investigation covers issues in Laminin, Cell biology, Embryonic stem cell, Basement membrane assembly and Molecular biology. As a part of the same scientific family, David Edgar mostly works in the field of Laminin, focusing on Cell adhesion and, on occasion, Cell–cell interaction. His Cell biology study incorporates themes from Cell culture, Cellular differentiation and Nerve growth factor.
The various areas that he examines in his Embryonic stem cell study include Progenitor cell, Stem cell, Enteric nervous system and Pathology. David Edgar has included themes like Epithelium, Immunology, Interstitial cell of Cajal, Epiblast and Embryoid body in his Stem cell study. His research in Basement membrane assembly intersects with topics in EGF-like domain, Dystroglycan, Stereochemistry and Basement membrane.
His primary areas of investigation include Cell biology, Laminin, Embryonic stem cell, Pathology and Stem cell. His work deals with themes such as Cell culture, Cellular differentiation, Nerve growth factor, Immunology and Embryoid body, which intersect with Cell biology. Within one scientific family, David Edgar focuses on topics pertaining to Epithelium under Embryoid body, and may sometimes address concerns connected to Basement membrane assembly.
He combines subjects such as Molecular biology, Glycoprotein, Protein subunit and Basement membrane with his study of Laminin. His work in Embryonic stem cell tackles topics such as Cell adhesion which are related to areas like Biophysics. The Pathology study combines topics in areas such as Progenitor cell, Transplantation and Enteric nervous system.
His main research concerns Cell biology, Stem cell, Embryonic stem cell, Cellular differentiation and Progenitor cell. His Cell biology study integrates concerns from other disciplines, such as Germ layer and Immunology. His Embryonic stem cell research is multidisciplinary, incorporating elements of Cell culture, Epithelium, Cell growth, Cell adhesion and Mesenchymal stem cell.
As part of the same scientific family, David Edgar usually focuses on Cell culture, concentrating on Cell and intersecting with Extracellular matrix. His Cellular differentiation research includes themes of Endothelial stem cell, Cell type and Mesoderm. His Progenitor cell research is multidisciplinary, incorporating perspectives in Neurosphere and Pathology.
David Edgar mainly investigates Embryonic stem cell, Cellular differentiation, Cell biology, Cell culture and Cell adhesion. His work on Embryoid body as part of his general Embryonic stem cell study is frequently connected to Rac GTP-Binding Proteins, thereby bridging the divide between different branches of science. His work carried out in the field of Cellular differentiation brings together such families of science as Endothelial stem cell and Immunology.
The study incorporates disciplines such as Epithelium and Germ layer in addition to Cell biology. David Edgar has researched Cell culture in several fields, including Cell morphology, Biophysics, Cell growth and Optics. His Cell adhesion research incorporates themes from Fibronectin, Extracellular matrix and Terahertz radiation.
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A simplified laminin nomenclature
Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann.
Matrix Biology (2005)
Absence of Basement Membranes after Targeting the LAMC1 Gene Results in Embryonic Lethality Due to Failure of Endoderm Differentiation
Neil Smyth;H. Seda Vatansever;Patricia Murray;Michael Meyer.
Journal of Cell Biology (1999)
Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation
Shaohua Li;David Harrison;Salvatore Carbonetto;Salvatore Carbonetto;Reinhard Fässler.
Journal of Cell Biology (2002)
The role of laminin in embryonic cell polarization and tissue organization.
Shaohua Li;David Edgar;Reinhard Fässler;William Wadsworth.
Developmental Cell (2003)
The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.
M Aumailley;V Nurcombe;D Edgar;M Paulsson.
Journal of Biological Chemistry (1987)
Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain.
Rainer Deutzmann;Monique Aumailley;Hanna Wiedemann;Werner Pysny.
FEBS Journal (1990)
Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture.
Ulrike Dohrmann;David Edgar;Michael Sendtner;Hans Thoenen.
Developmental Biology (1986)
Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies.
David Edgar;Rupert Timpl;Hans Thoenen.
Journal of Cell Biology (1988)
Subpopulations of cultured chick sympathetic neurones differ in their requirements for survival factors
David Edgar;Yves-Alain Barde;Hans Thoenen.
Nature (1981)
Regulation of Programmed Cell Death by Basement Membranes in Embryonic Development
Patricia Murray;David Edgar.
Journal of Cell Biology (2000)
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