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Genetics

D-Index
70
Citations
19101
World Ranking
2267
National Ranking
1018

Overview

Kiyoshi Mizuuchi is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology and genetics subfields. The scientist's work spans topics including bacterial genetics and biotechnology, DNA repair mechanisms, RNA and protein synthesis mechanisms, bacteriophages and microbial interactions, genomics and phylogenetic studies, antibiotic resistance in bacteria, and aluminum alloys composites properties.

Recent scholarly contributions include research articles published between 2021 and 2022. Notable publications are:

  • CTP and parS coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning, 2021, eLife
  • CTP and parS coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Distinct architectural requirements for the parS centromeric sequence of the pSM19035 plasmid partition machinery, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Distinct architectural requirements for the parS centromeric sequence of the pSM19035 plasmid partition machinery, 2022, eLife
  • Enhancing Metal-Matrix Composites Performance via Spark Plasma Sintering (SPS) Process, 2022, Journal of the Japan Society of Powder and Powder Metallurgy

Kiyoshi Mizuuchi has collaborated frequently with several researchers, including:

  • Jagat B. Budhathoki
  • James A. Taylor
  • Yeonee Seol
  • Keir C. Neuman
  • Andrea Volante

The scientist's work has been published in a variety of academic venues, reflecting their multidisciplinary approach. The main publication venues include:

  • eLife
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the Japan Society of Powder and Powder Metallurgy
  • Biophysical Journal

The research topics addressed by Mizuuchi often integrate molecular and genetic mechanisms with applied materials science, as evidenced by published works ranging from bacterial genetic partitioning systems to metal-matrix composite performance enhancements via sintering techniques. This cross-disciplinary approach aligns with subfield contributions in molecular medicine and mechanical engineering alongside molecular biology and genetics.

Best Publications

  • DNA gyrase: an enzyme that introduces superhelical turns into DNA

    Martin Gellert;Kiyoshi Mizuuchi;Mary H. O'Dea;Howard A. Nash

  • Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

    Martin Gellert;Kiyoshi Mizuuchi;Mary H. O'Dea;Tateo Itoh

  • CRYSTAL STRUCTURE OF AN IHF-DNA COMPLEX : A PROTEIN-INDUCED DNA U-TURN

    Phoebe A Rice;Shu-wei Yang;Kiyoshi Mizuuchi;Howard A Nash

  • HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

    Alan Engelman;Kiyoshi Mizuuchi;Robert Craigie

  • V(D)J recombination: a functional definition of the joining signals.

    Joanne E. Hesse;Michael R. Lieber;Kiyoshi Mizuuchi;Martin Gellert

  • Transpositional recombination : mechanistic insights from studies of Mu and other elements

    Kiyoshi Mizuuchi

  • Retroviral DNA integration: Structure of an integration intermediate

    Tamio Fujiwara;Kiyoshi Mizuuchi

  • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination

    Michael R. Lieber;Joanne E. Hesse;Susanna Lewis;Gayle C. Bosma

  • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals.

    Joanne E. Hesse;Joanne E. Hesse;Michael R. Lieber;Michael R. Lieber;Martin Gellert;Martin Gellert;Kiyoshi Mizuuchi;Kiyoshi Mizuuchi

  • Similarities Between Initiation of V(D)J Recombination and Retroviral Integration

    Dik C. van Gent;Kiyoshi Mizuuchi;Martin Gellert

  • DNA gyrase: subunit structure and ATPase activity of the purified enzyme.

    Kiyoshi Mizuuchi;Mary H. O'Dea;Martin Gellert

  • Barrier-to-autointegration factor (BAF) bridges DNA in a discrete, higher-order nucleoprotein complex

    Ronglan Zheng;Rodolfo Ghirlando;Myung Soo Lee;Kiyoshi Mizuuchi

  • Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration.

    P Rice;K Mizuuchi

  • DNA gyrase action involves the introduction of transient double-strand breaks into DNA

    K Mizuuchi;L M Fisher;M H O'Dea;M Gellert

  • The phage Mu transpososome core: DNA requirements for assembly and function.

    H Savilahti;P A Rice;K Mizuuchi

  • Site-specific recognition of the bacteriophage mu ends by the mu a protein

    Robert Craigie;Michiyo Mizuuchi;Kiyoshi Mizuuchi

  • Developmental stage specificity of the lymphoid V(D)J recombination activity.

    M R Lieber;J E Hesse;K Mizuuchi;M Gellert

  • A defined system for the DNA strand-transfer reaction at the initiation of bacteriophage Mu transposition: protein and DNA substrate requirements

    Robert Craigie;Donna J. Arndt-Jovin;Kiyoshi Mizuuchi

  • Transposition of Mu DNA: Joining of Mu to target DNA can be uncoupled from cleavage at the ends of Mu

    Robert Craigie;Kiyoshi Mizuuchi

  • Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

    Michael R. Lieber;Joanne E. Hesse;Kiyoshi Mizuuchi;Martin Gellert

Frequent Co-Authors

Martin Gellert
Martin Gellert National Institute of Diabetes and Digestive and Kidney Diseases
Robert Craigie
Robert Craigie National Institutes of Health
Michael R. Lieber
Michael R. Lieber University of Southern California
Robert T. Clubb
Robert T. Clubb University of California, Los Angeles
Phoebe A. Rice
Phoebe A. Rice University of Chicago
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh
Rodolfo Ghirlando
Rodolfo Ghirlando National Institutes of Health
Howard A. Nash
Howard A. Nash MRC Laboratory of Molecular Biology
Alan Engelman
Alan Engelman Harvard University

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