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Christopher E.M. Griffiths

Christopher E.M. Griffiths

D-Index & Metrics

Medicine

D-Index
139
Citations
77122
World Ranking
1749
National Ranking
179

Research.com Recognitions

  • 2015 - Member of Academia Europaea

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Disease
  • Gene

His primary areas of investigation include Psoriasis, Internal medicine, Dermatology, Immunology and Surgery. Christopher E.M. Griffiths combines subjects such as Quality of life and Disease with his study of Psoriasis. His Internal medicine research incorporates elements of Gastroenterology, Placebo and Endocrinology.

Tretinoin and Negroid is closely connected to Chemotherapy in his research, which is encompassed under the umbrella topic of Dermatology. His studies in Surgery integrate themes in fields like Cohort study, Confidence interval and Ustekinumab. His study in Guselkumab is interdisciplinary in nature, drawing from both Etanercept and Risankizumab.

His most cited work include:

  • Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence (1192 citations)
  • Secukinumab in plaque psoriasis--results of two phase 3 trials. (1146 citations)
  • Pathogenesis and clinical features of psoriasis. (1130 citations)

What are the main themes of his work throughout his whole career to date?

Psoriasis, Internal medicine, Dermatology, Immunology and Pathology are his primary areas of study. His study in Psoriasis focuses on Psoriasis Area and Severity Index in particular. His Psoriasis Area and Severity Index research is multidisciplinary, relying on both Dermatology Life Quality Index, Adverse effect and Severity of illness.

His Internal medicine study integrates concerns from other disciplines, such as Placebo, Endocrinology and Surgery. Christopher E.M. Griffiths works mostly in the field of Endocrinology, limiting it down to topics relating to Human skin and, in certain cases, Retinoic acid, as a part of the same area of interest. Christopher E.M. Griffiths has researched Dermatology in several fields, including Chemotherapy and MEDLINE.

He most often published in these fields:

  • Psoriasis (60.87%)
  • Internal medicine (29.12%)
  • Dermatology (23.45%)

What were the highlights of his more recent work (between 2018-2021)?

  • Psoriasis (60.87%)
  • Internal medicine (29.12%)
  • MEDLINE (8.83%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Psoriasis, Internal medicine, MEDLINE, Psoriasis Area and Severity Index and Dermatology. The study incorporates disciplines such as Clinical trial, Intensive care medicine, Disease, Etanercept and Cohort in addition to Psoriasis. He usually deals with Disease and limits it to topics linked to General partnership and Systematic review and Nursing.

His MEDLINE research incorporates themes from Global health, Physiology, Seasonality and Circadian rhythm. His Psoriasis Area and Severity Index study combines topics in areas such as Odds ratio, Dermatology Life Quality Index, Adverse effect and Dosing. In his study, Gastroenterology is strongly linked to Moderate to severe, which falls under the umbrella field of Dermatology.

Between 2018 and 2021, his most popular works were:

  • Clinical applications of machine learning algorithms: beyond the black box. (84 citations)
  • HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis (41 citations)
  • Clinical and genetic differences between pustular psoriasis subtypes (38 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Disease

His primary scientific interests are in Psoriasis, Internal medicine, Psoriasis Area and Severity Index, Cohort and Ustekinumab. His study deals with a combination of Psoriasis and Systemic therapy. Christopher E.M. Griffiths interconnects Dermatology Life Quality Index, Bioinformatics, Transcriptome, Randomized controlled trial and Confidence interval in the investigation of issues within Psoriasis Area and Severity Index.

He combines subjects such as Placebo and Interleukin 17 with his study of Randomized controlled trial. The study incorporates disciplines such as Dermatology, Acrodermatitis, Therapeutic drug monitoring and Cohort study in addition to Cohort. His work focuses on many connections between Ustekinumab and other disciplines, such as Clinical trial, that overlap with his field of interest in Propensity score matching and Number needed to treat.

Best Publications

  • Pathogenesis and clinical features of psoriasis.

    Christopher E. M. Griffiths;Jonathan N. W. N. Barker

  • Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence

    Rosa Parisi;Deborah P.M. Symmons;Christopher E.M. Griffiths;Darren M. Ashcroft

  • Secukinumab in plaque psoriasis--results of two phase 3 trials.

    Richard G. Langley;Boni E. Elewski;Mark Lebwohl;Kristian Reich

  • Psoriasis: epidemiology, clinical features, and quality of life

    R G B Langley;G G Krueger;C E M Griffiths

  • Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial

    Andrew Blauvelt;Marjolein de Bruin-Weller;Melinda Gooderham;Jennifer C. Cather

  • Infliximab induction and maintenance therapy for moderate-to-severe psoriasis : a phase III, multicentre, double-blind trial

    Kristian Reich;Frank O Nestle;Kim Papp;Jean-Paul Ortonne

  • British guideline on the management of asthma: A national clinical guideline

    Graham Douglas;Bernard Higgins;Neil Barnes;Anne Boyter

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis

    Christopher E.M. Griffiths;Bruce E. Strober;Peter van de Kerkhof;Vincent Ho

  • Definition of treatment goals for moderate to severe psoriasis: a European consensus

    U. Mrowietz;K. Kragballe;K. Reich;P. Spuls

  • Keratinocytes as initiators of inflammation

    Jonathan N. W. N. Barker;C. E. M. Griffiths;Brian J. Nickoloff;R. S. Mitra

  • European S3-guidelines on the systemic treatment of psoriasis vulgaris

    D Pathirana;AD Ormerod;P Saiag;Catherine Smith

  • Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparator–controlled VOYAGE 1 trial

    Andrew Blauvelt;Kim A. Papp;Christopher E.M. Griffiths;Bruce Randazzo;Bruce Randazzo

  • A global phase III randomized controlled trial of etanercept in psoriasis : safety, efficacy, and effect of dose reduction

    Kim A. Papp;S. Tyring;M. Lahfa;J. Prinz

  • Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials

    Christopher E M Griffiths;Kristian Reich;Mark Lebwohl;Peter van de Kerkhof

  • National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study

    Rosa Parisi;Ireny Y K Iskandar;Evangelos Kontopantelis;Matthias Augustin

  • Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial

    T N Brooklyn;M G S Dunnill;A Shetty;J J Bowden

  • Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

    Kim Papp;Kristian Reich;Craig L. Leonardi;Leon Kircik

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

Frequent Co-Authors

Jonathan Barker
Jonathan Barker King's College London
Catherine Smith
Catherine Smith King's College London
John J. Voorhees
John J. Voorhees University of Michigan–Ann Arbor
Helen L. Richards
Helen L. Richards University of Manchester
Dónal G. Fortune
Dónal G. Fortune University of Limerick
Jane Worthington
Jane Worthington University of Manchester
Kim Papp
Kim Papp Probity Medical Research
Ian Kimber
Ian Kimber University of Manchester
Ralf Paus
Ralf Paus University of Miami
Chris J. Main
Chris J. Main Keele University

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