Nick Morrice

Overview

Best Publications

• Mechanism of activation of protein kinase B by insulin and IGF-1.

  Dario R. Alessi;Mirjana Andjelkovic;Barry Caudwell;Peter Cron

  3814
  Citations

• LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

  Jose M Lizcano;Olga Göransson;Rachel Toth;Maria Deak

  1558
  Citations

• 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

  Dario R. Alessi;Maria Deak;Antonio Casamayor;F. Barry Caudwell

  986
  Citations

• 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

  Dario R. Alessi;Mark T. Kozlowski;Qing-Ping Weng;Nick Morrice

  757
  Citations

• Aurora B Regulates MCAK at the Mitotic Centromere

  Paul D Andrews;Yulia Ovechkina;Nick Morrice;Michael Wagenbach

  675
  Citations

• The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

  Alberto C. Vitari;Maria Deak;Nick A. Morrice;Dario R. Alessi

  668
  Citations

• Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK

  Lindsey A. Allan;Nick Morrice;Suzanne Brady;Gareth Magee

  597
  Citations

• Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

  Takayasu Kobayashi;Maria Deak;Nick Morrice;Philip Cohen

  569
  Citations

• 14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.

  Mercedes Pozuelo Rubio;Kathryn M Geraghty;Barry H C Wong;Nicola T Wood

  567
  Citations

• MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

  Jérôme Boudeau;Annette F. Baas;Maria Deak;Nick A. Morrice

  535
  Citations

• Activation of the tumour suppressor kinase LKB1 by the STE20‐like pseudokinase STRAD

  A.F. Baas;J. Boudeau;G.P. Sapkota;L. Smit

  480
  Citations

• An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation

  Bénédicte Manoury;Eric W. Hewitt;Nick Morrice;Pam M. Dando

  472
  Citations

• Identification of Regulatory Phosphorylation Sites in Mitogen-activated Protein Kinase (MAPK)-activated Protein Kinase-1a/p90 rsk That Are Inducible by MAPK

  Kevin N. Dalby;Nick Morrice;F. Barry Caudwell;Joseph Avruch

  461
  Citations

• Activation of the thiazide-sensitive Na+-Cl– cotransporter by the WNK-regulated kinases SPAK and OSR1

  Ciaran Richardson;Fatema H. Rafiqi;Håkan K. R. Karlsson;Ntsane Moleleki

  455
  Citations

• DNA‐PK autophosphorylation facilitates Artemis endonuclease activity

  Aaron A Goodarzi;Yaping Yu;Enriqueta Riballo;Pauline Douglas

  425
  Citations

• Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

  Antonio Casamayor;Nick A. Morrice;Dario R. Alessi

  416
  Citations

• Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1

  Carina I. Holmberg;Ville Hietakangas;Andrey Mikhailov;Jouni O. Rantanen

  413
  Citations

• Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

  Alberto C. Vitari;Jacob Thastrup;Fatema H. Rafiqi;Maria Deak

  396
  Citations

• Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

  James T. Murray;David G. Campbell;Nicholas Morrice;Gillian C. Auld

  394
  Citations

• Phosphorylation of the Protein Kinase Mutated in Peutz-Jeghers Cancer Syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent Protein Kinase, but Not Its Farnesylation at Cys433, Is Essential for LKB1 to Suppress Cell Growth

  Gopal P. Sapkota;Agnieszka Kieloch;Jose M. Lizcano;Sonia Lain

  386
  Citations